Red cell distribution width in relation to stroke

INTRODUCTION: Stroke has now become the second leading cause of death worldwide. Stroke is an important cause for prolonged disability. Given this immense burden that stroke exerts, there becomes the need to develop more precise estimates of a stroke survivors prognosis and it remains an very important goal. And also identification of predictors of mortality is very vital so that we can institute many prompt therapeutic measures to improve outcome. RDW play an important role to assess the mortality and morbidity in acute CVA. So, high RDW has been studied in relation to stroke. AIMS AND OBJECTIVE: 1. To study the Red Cell Distribution Width in relation to stroke in Medicine department in RGGGH, Chennai – 03 2. To study the importance of determining Red Cell distribution width to assess the severity of ischemic stroke. METHODS: The study was conducted at the Institute of Internal Medicine, Rajiv Gandhi Government General Hospital (RGGGH), Madras Medical College, Chennai in 50 patients who were admitted in medical ward. RESULTS: According to this study p value of comparison of RDW for NIHSS Classification COMPARISON OF RDW according to MRS is < 0.001 which is significant. A higher values of RDW is a predictor of poor prognosis for stroke. CONCLUSION: A higher values of Red cell Distribution Width (RDW) is a predictor of severity of ischemic stroke. A higher values of Red cell Distribution Width (RDW) on admission is a predictor of poor prognosis for stroke

Analysis, design and investigation on a new single-phase switched quasi Z-source inverter for photovoltaic application

Abstract: This paper addresses the approach to improve the efficiency of the quasi Z-source inverter. In order to increase the efficiency the reduction of conduction losses is one way to approach. Sequentially to decrease the conduction losses in the quasi z-source inverter the replacement of diode is replacing with switches is proposed which is also called as synchronous rectification. The paper represents basics of the approach, analysis and comparison of the power losses of the traditional and proposed designs of the grid connected PV-system with quasi z-source inverter system. The proposed approach validated on the computer simulations in the MATLAB environment

eNOS Protects from Atherosclerosis Despite Relevant Superoxide Production by the Enzyme in apoE−/− Mice

All three nitric oxide synthase (NOS) isoforms are expressed in atherosclerotic plaques. NOS enzymes in general catalyse NO production. However, under conditions of substrate and cofactor deficiency, the enzyme directly catalyse superoxide formation. Considering this alternative chemistry, the effects of NOS on key events in spontaneous hyperlipidemia driven atherosclerosis have not been investigated yet. Here, we evaluate how endothelial nitric oxide synthase (eNOS) modulates leukocyte/endothelial- (L/E) and platelet/endothelial- (P/E) interactions in atherosclerosis and the production of nitric oxide (NO) and superoxide by the enzyme. Intravital microscopy (IVM) of carotid arteries revealed significantly increased L/E-interactions in apolipoproteinE/eNOS double knockout mice (apoE(-/-)/eNOS(-/-)), while P/E-interactions did not differ, compared to apoE(-/-). eNOS deficiency increased macrophage infiltration in carotid arteries and vascular cell adhesion molecule-1 (VCAM-1) expression, both in endothelial and smooth muscle cells. Despite the expression of other NOS isoforms (inducible NOS, iNOS and neuronal NOS, nNOS) in plaques, Electron Spin Resonance (ESR) measurements of NO showed significant contribution of eNOS to total circulating and vascular wall NO production. Pharmacological inhibition and genetic deletion of eNOS reduced vascular superoxide production, indicating uncoupling of the enzyme in apoE(-/-) vessels. Overt plaque formation, increased vascular inflammation and L/E- interactions are associated with significant reduction of superoxide production in apoE(-/-)/eNOS(-/-) vessels. Therefore, lack of eNOS does not cause an automatic increase in oxidative stress. Uncoupling of eNOS occurs in apoE(-/-) atherosclerosis but does not negate the enzyme's strong protective effects

ABSTRACT

ABSTRACT In this study the physical fitness of 100 healthy adolescents (50 boys/50 girls) aged 12-16 yrs were assessed for physical fitness by measuring Vo2max using the treadmill and related with BMI, heart rate and waist circumference. 27% of adolescents had achieved an average to good Vo2max and 73% low -fair Vo2max. The boys had attained better Vo2max than girls. The Vo2 max in boys and girls increased from a BMI of 15-16kg/m 2 to reach a peak at 17-19kg/m 2 and 18-19 kg/m2 respectively and thereafte

The bibliometric analysis of previous twenty- five years’ literature: A microfinance review

The tremendous increase in publications in Microfinance since 2000 has highlighted need for and importance of innovative techniques to present big data in this field in a most informative, scientific, and summarized manner. The study highlights the trends and patterns of Microfinance literature by revealing what has been done and what could be done in future. The study comprises of 1429 microfinance publications extracted from the Scopus database. The authors adopt bibliometric analysis through open software application R and network analysis techniques using Gephi AND VOS viewer software. The study adds a valuable contribution to the field of Microfinance by distinctively summarizing the important literature. It identifies global academic research trends and provides insights about trending topics, highly cited literature, authors, countries, collaboration network, word cloud, citation analysis, etc. Finally based on extensive literature survey through bibliometric analysis. The study highlights about the scope of future research in Microfinance

A survey on skin cancer detection using skin temperature variation analysis

All over the world, in recent years people were suffering from various types of cancer, the skin cancer becomes emerging in that. In India about 2 in 10 cases people are suffering from Melanoma type of skin cancer. In recent years there is no cancer screening tool available for early diagnosis of skin cancer. The existing method, skin cancer can be detected by the doctors (or) self-examination by the person (or) through certain technique which can capture only images (or) through invasive method like biopsy in the abnormal cell proliferated region. Proposed system is implementation of infrared thermal sensor in a noncontact manner which detects the temperature of the epidermal layer of skin, where the temperature of the skin varies for the subjects if they are suffering from cancer

Skin cancer detection using non-invasive techniques

Skin cancer is the most common form of cancer and is globally rising. Historically, the diagnosis of skin cancers has depended on various conventional techniques which are of an invasive manner. A variety of commercial diagnostic tools and auxiliary techniques are available to detect skin cancer. This article explains in detail the principles and approaches involved for non-invasive skin cancer diagnostic methods such as photography, dermoscopy, sonography, confocal microscopy, Raman spectroscopy, fluorescence spectroscopy, terahertz spectroscopy, optical coherence tomography, the multispectral imaging technique, thermography, electrical bio-impedance, tape stripping and computer-aided analysis. The characteristics of an ideal screening test are outlined, and the authors pose several points for clinicians and scientists to consider in the evaluation of current and future studies of skin cancer detection and diagnosis. This comprehensive review critically analyses the literature associated with the field and summarises the recent updates along with their merits and demerits