Responsible conduct of Research: Concept and Issues in Authorship

In scholarly publication, authorship defines the roles played by an individual or a member of a team in creating and circulating an original work. It is therefore important to clearly understand who deserves to be an author in a publication. Also, the order or position of authors in a scholarly publication often leads to conflict among members of research teams. This is not helped by the advent of more technical reward systems for promotion, tenure and grants in many institutions, some of which give advantage to the position of some authors. In this paper, some common issues on authorship and peer review processes are discusse

Drinking water service level of groundwater sources in Lambo Lasunwon community, Ikorodu, Lagos

Groundwater from aquifers is a major source of potable water supply, particularly for communities not connected to municipal drinking water system. This paper discusses the performance of the service level of on-site private water system from ground water in Lambo Lasunwon Community, Ikorodu. Reconnaissance survey, co-ordinates and heights above sea level of water sample points were obtained. Structured questionnaires were administered on two hundred and seven (207) inhabitants within the community. Social parameters were examined; physical, chemical and microbiological test were carried out samples. The result shows 56% of those interviewed have water in their compound, with 78.4% being borehole, with 77.3% residential. Average water cost is $0.13 per 50liters, daily water usage 50-150litres. Coliform count was zero, with Lead (Pb) of 0.03 – 0.557mg/l, Iron (Fe) 0.181 – 0.367mg/l but slightly acidic with pH value range of 4.76 -5.31

An Evaluation of Property Portfolio Diversification Strategies in Nigeria.

This paper identifies diversification strategies adopted in the Nigerian property market and evaluates the effectiveness of the strategies with a view to determining the benefits of each strategy to investors and also moves the profession in Nigeria forward towards meeting the global trends. This is against the background of greater unpredictability and volatility in the Nigeria property market and the increasing need for investors to diversify risk of their portfolios. Questionnaires backed up with interviews, were administered on 28 institutional property investors in Lagos, Abuja and Port-Harcourt metropolitan areas. Pooled data on rental transactions and capital values for the period of 1998 – 2003 involving 76 properties were also collected from the investors. Data were analysed with the use of frequency distribution, relative importance index, Sharpe’s Index and mean/standard deviation ratio. The study’s results showed that “property type” and “geographic naïve diversification” were the preferred strategies in the Nigerian property market and that these strategies did not give the best protection to investors’ portfolios against the risk situation in the market. The results of the evaluation revealed that the best strategy would be to adopt efficient portfolio strategy and invest better proportions of a real estate portfolio in residential properties located in Lagos metropolitan area

Development of a Stope Stability Prediction Model Using Ensemble Learning Techniques - A Case Study

The consequences of collapsed stopes can be dire in the mining industry. This can lead to the revocation of a mining license in most jurisdictions, especially when the harm costs lives. Therefore, as a mine planning and technical services engineer, it is imperative to estimate the stability status of stopes. This study has attempted to produce a stope stability prediction model adopted from stability graph using ensemble learning techniques. This study was conducted using 472 case histories from 120 stopes of AngloGold Ashanti Ghana, Obuasi Mine. Random Forest, Gradient Boosting, Bootstrap Aggregating and Adaptive Boosting classification algorithms were used to produce the models. A comparative analysis was done using six classification performance metrics namely Accuracy, Precision, Sensitivity, F1-score, Specificity and Mathews Correlation Coefficient (MCC) to determine which ensemble learning technique performed best in predicting the stability of a stope. The Bootstrap Aggregating model obtained the highest MCC score of 96.84% while the Adaptive Boosting model obtained the lowest score. The Specificity scores in decreasing order of performance were 98.95%, 97.89%, 96.32% and 95.26% for Bootstrap Aggregating, Gradient Boosting, Random Forest and Adaptive Boosting respectively. The results showed equal Accuracy, Precision, F1-score and Sensitivity score of 97.89% for the Bootstrap Aggregating model while the same observation was made for Adaptive Boosting, Gradient Boosting and Random Forest with 90.53%, 92.63% and 95.79% scores respectively. At a 95% confidence interval using Wilson Score Interval, the results showed that the Bootstrap Aggregating model produced the minimal error and hence was selected as the alternative stope design tool for predicting the stability status of stopes.   Keywords: Stope Stability, Ensemble Learning Techniques, Stability Graph, Machine Learnin

Application of Split Desktop Image Analysis and Kuz-Ram Empirical Model for Evaluation of Blast Fragmentation Efficiency in a Typical Granite Quarry

Evaluation of fragmentation efficiency is an integral aspect of blasting operation. This study therefore assesses the efficiency of fragmentation size at Eminent granite quarry, Ibadan, Nigeria using Split Desktop software and Kuz-Ram empirical model. Five muckpiles of blasted rocks with the same blast design were analysed. The muckpile images were captured using smart high precision digital camera and uploaded into computer for Split Desktop analysis. The results of the fragment size distribution obtained from Kuz-Ram vary slightly with that of the Split Desktop but follow similar trend. The average values of F80 and F90 from the Split Desktop image analysis were 90.96 cm and 98.24 cm respectively. The Kuz-Ram model values for F80 and F90 were 88.52 cm and 92.95 cm respectively. The results of the Split Desktop were compared to the results obtained from the Kuz-Ram experiential model. The findings showed that the results obtained from Kuz-Ram empirical model were in conformity with the results from the Split Desktop software based on empirical relationship. Hence, the model is good for preliminary evaluation of blast design.   Keywords: Blasting, Particle Size Distribution, Split Desktop Software, Muckpile, Fragmentation Indicato

Service level delivery of municipal and private water sources in Olodi-Apapa, Ajeromi-Ifelodun LGA, Lagos

The service level delivery of municipal water supply and private groundwater sources in Olodi-Apapa, Lagos was evaluated. Reconnaissance survey, co-ordinates and heights above sea level of water sample points were obtained. Structured questionnaires retrieved from two hundred and forty seven (247) inhabitants (98.8%) were analyzed. The result shows a low income area with 72.9% in room apartments, 90.3% uses untreated water supply, with only 6.5% from the municipal source, while private borehole and well accounts for 55.8% and 37.7% respectively. Use of generating set for water abstraction was by 77.3%, while 93.5% do not have access to public water supply, 100% of the sources have high calcium hardness and over 60% have high chloride content. Municipal micro water works limitations include expansion, electricity supply, and good network of public standing pipes

A patient-initiated DMARD selfmonitoring service for people with rheumatoid or psoriatic arthritis on methotrexate: a randomised controlled trial

Objective: To determine the effectiveness of a patient-initiated DMARD self-monitoring service for people with rheumatoid (RA) or psoriatic arthritis (PsA) on methotrexate. Methods: A two-arm, single centre, randomised controlled trial assessing superiority in relation to healthcare utilisation, clinical and psychosocial outcomes. Participants were 100 adults with either RA or PsA on a stable dose of methotrexate, randomly assigned to usual care or the patient-initiated service. Intervention participants were trained how to understand and interpret their blood tests and use this information to initiate care from their clinical nurse specialist (CNS). The primary outcome was the number of outpatient visits to the CNS during the trial period. Differences between groups were analysed using Poisson regression models. Secondary outcomes were collected at baseline and after the 3rd and 6th blood tests. Disease activity was measured using either the DAS28 or PsARC, pain and fatigue using a visual numeric scale and the HAQII, HADS and SF12 were completed to assess disability, mood and quality of life, respectively. Differences between groups over time on secondary outcomes were analysed using multi-level models. Results: The patient-initiated DMARD self-monitoring service was associated with 54.55% fewer visits to the CNS (p<0.0001), 6.80% fewer visits to the rheumatologist (p=0.23) and 38.80% fewer visits to the GP (p=0.07), compared with control participants. There was no association between trial arm and any of the clinical or psychosocial outcomes. Conclusions: The results suggest that a patient-initiated service that incorporates patients self-monitoring DMARD therapy can lead to significant reductions in healthcare utilisation, whilst maintaining clinical and psychosocial well-being

HPLC quantification of phenolic content and assessment of methanolic extract of Antiaris africana for toxicological study

The study was aimed at evaluating the toxicological and antioxidant activities of Antiaris africana Engl. (family Moraceae), that is used in Nigeria and other West Africa countries as a panacea for the treatment of several ailments. The methanolic extract of A. africana (MEA) obtained was analysed for antioxidant activities in vitro and screened for various phytochemicals present. Phenolic and flavonoid contents were determined followed with high performance liquid chromatography -diode-array detection (HPLC-DAD) fingerprinting of phenolic content. Furthermore, the sub-acute toxicity of MEA was determined via oral administration of varying doses for 14 consecutive days (0, 50, 100, 200 and 400 mg/kg) in rats. After oral administration for 14 consecutive days in male rats, the toxicity effect was assayed by determining aspartate aminotransferase (AST) and alanine aminotransferase (ALT) for hepatic function; urea and creatinine for renal function; creatinine kinase (CK) for cardiac function; and lipid profile. HPLC results showed that the major phenolics present are quercetin, rutin, caffeic acid, garlic acid and quercetin. MEA was able to scavenge diphenyl picryl hydrazyl, hydroxyl and nitric oxide radicals and prevent lipid peroxidation induced by ferrous sulphate at all concentration tested. The toxicology investigation showed that at low doses, A. africana is non-toxic, while at high doses; it is moderately toxic to the animals. In conclusion, A. Africana is generally non-toxic; however, care must be taken in administration at higher doses.Keywords: Toxicology, HPLC, phytochemicals, Antiaris african

Chrysophyllum Albidum Accelerates Delayed Gastric Ulcer Healing in Rats Through Oxidative Stress Reversal and Proton Pump Inhibition

Background: Chrysophyllum albidum has been documented to exert its gastric ulcer (GU) healing activities by modulating blood inflammatory mediators, however, other probable in-vivo underlying mechanisms are still vague which this study sought to investigate.Materials and Methods: Male Wistar rats (120-130g) divided into 9 groups (n=15 for groups I-VII; n=5 for groups VIII &amp; IX) viz: Groups I- positive control (DUnA); II and III–250 and 500mg/kg methanolic extract of C. albidum (MeCaB) bark respectively; IV, V and VI-100mg/kg fractions A, B and C respectively; VII–30mg/kg omeprazole; VIII-ulcerated untreated (baseline), IX-negative control. Chronic GU was induced experimentally and delayed using indomethacin with 14 days simultaneous drug treatment. Gastric ulcer score, mucin content, antioxidant and proton pump activities were evaluated by days 3, 7 and 14 of treatment. Data were expressed as Mean+SEM and P&lt;0.05 was significant.Results: C. albidum and fractions treated groups significantly decreased gastric ulcer scores and lipid peroxidation compared with DUnA. Negative control, C. albidum and fraction treated groups significantly increased superoxide dismutase, catalase, glutathione levels and mucin content compared with DUnA group by days 3 and 7. C. albidum, Negative and baseline control groups significantly decreased H+K+ATPase activities compared with DUnA by day14.Conclusion: C. albidum and its fractions facilitated the healing of gastric ulcer, probably by enhanced antioxidant levels, mucin content and decreased gastric H+K+ATPase activity. Keywords: C. albidum and chromatographic fractions, gastric ulcer healing, mucin , antioxidant, H+/K+ATPase pump