391 research outputs found
Walter Campbell:A distinguished life
An efficient and simple synthesis approach to form stable (68) Ga-labeled nanogels is reported and their fundamental properties investigated. Nanogels are obtained by self-assembly of amphiphilic statistical prepolymers derivatised with chelating groups for radiometals. The resulting nanogels exhibit a well-defined spherical shape with a diameter of 290 +/- 50 nm. The radionuclide (68) Ga is chelated in high radiochemical yields in an aqueous medium at room temperature. The phagocytosis assay demonstrates a highly increased internalization of nanogels by activated macrophages. Access to these (68) Ga-nanogels will allow the investigation of general behavior and clearance pathways of nanogels in vivo by nuclear molecular imaging
What is a True Gamer? The Male Gamer Stereotype and the Marginalization of Women in Video Game Culture
This is the author accepted manuscript. The final version is available from Springer Verlag via the DOI in this record.Women and men play video games in approximately equal numbers. Despite this similarity, video gaming is still strongly associated with men. A common justification for this stereotype is that, although women might play games, they should not be considered âtrueâ or âhard-coreâ gamers because they play more casually and less skillfully compared to their male counterparts. In this contribution, we review the existing literature on gender and gaming to investigate the male gamer stereotype in terms of its accuracy, persistence, effects, and future perspective. We conclude that the stereotype varies in accuracy depending on the definition of âgamer.â We further argue that the persistence of this stereotype can be explained by the fact that almost all professional and highly visible figures in gaming culture are male. On the other hand, female players who achieve a moderate level of competence are rendered invisible or are actively marginalized. We argue that the effects of the male gamer stereotype can be harmful to women, precluding them from the positive outcomes of video game play such as enhanced access to fields of science, technology, and engineering
Microscopic nanomechanical dissipation in gallium arsenide resonators
We report on a systematic study of nanomechanical dissipation in
high-frequency (approximatively 300 MHz) gallium arsenide optomechanical disk
resonators, in conditions where clamping and fluidic losses are negligible.
Phonon-phonon interactions are shown to contribute with a loss background
fading away at cryogenic temperatures (3 K). Atomic layer deposition of alumina
at the surface modifies the quality factor of resonators, pointing towards the
importance of surface dissipation. The temperature evolution is accurately
fitted by two-level systems models, showing that nanomechanical dissipation in
gallium arsenide resonators directly connects to their microscopic properties.
Two-level systems, notably at surfaces, appear to rule the damping and
fluctuations of such high-quality crystalline nanomechanical devices, at all
temperatures from 3 to 300K
The gendered nature and malleability of gamer stereotypes
This is the author accepted manuscript. The final version is available from Mary Ann Liebert via the DOI in this recordData availability: The data sets used in this paper are available at
https://osf.io/jfh9b/?view_only=f7de84580b8242e5b965a3b32ecdb6b9. All materials can be
found in the online supplement.Video gaming is seen as a male space. Female gamers are seen as atypical, have their
competence challenged, and face more harassment than male gamers do. This precarious position
is increasingly problematic as video gaming is now one of the most prevalent leisure activities,
providing an opportunity to both forge and maintain friendships, and to achieve social status and
career opportunities. We argue that the marginalization of female gamers is driven by masculine
gamer stereotypes. We investigate the content and gendered nature of gamer stereotypes as well
as their malleability in response to exposure to female gamers across two studies (NStudy 1=287;
NStudy 2=176). We explore the content of gamer stereotypes and find that they contain both
negative aspects, such as lacking social skills, and positive aspects, such as being competent and
agentic. Both studies demonstrate that gamer stereotypes are more similar to stereotypes of men
and boys than those of women and girls. In Study 2 we test whether exposure to a female gamer
can change the negative association between female stereotypes and gamer stereotypes, finding
support for this prediction. We conclude that gamer stereotypes are highly gendered but may be
malleable: increasing the visibility of female gamers could potentially reduce the incompatibility
between femininity and gaming
What proportion of the forest of small-scale owners is likely to be harvested: a Whanganui case study
National and regional wood supply forecasts indicate that small-scale forests will provide an increasing proportion of New Zealand's harvest volumes over the next decade. However these forecasts are based on physical factors only and do not consider harvest costs. Because of size, location and terrain, some small-scale forests may not he economic to harvest. In a case study, carried out in Whanganui District, the delivered wood cost including harvesting, roading and transportation, was estimated for a sample of 58 small-scale forest blocks. Taken into account were the size, slope, location and roading requirements of each block. Initial analysis, assuming harvesting at age 30 years, found a distribution of costs, with the majority of blocks in the range 87 a tonne, with an average of 100 a tonne. The optimum rotation age for these five blocks was found to be at least 49 years at which age costs are 107 a tonne. Given that average market prices for logs over the last five years in the region have been $84 a tonne, it is probable that these blocks will only be harvested at old ages and at times of exceptionally high average log prices. This study is based on generic assumptions about silviculture, yields and market destinations. However it indicates that five to 10 per cent of the area of small-scale blocks in the Whanganui District may never be harvested
Ferroelectric soft mode of polar ZnTiO3 investigated by Raman spectroscopy at high pressure
We explore the vibrational behavior and stability of ferroelectric ZnTiO3 under high pressure by Raman spectroscopy and second-harmonic-generation (SHG) measurements. Ab initio lattice-dynamics calculations have been employed to solve a controversy concerning the phonon-dispersion relations of ZnTiO3 and to carry out an assignment of the Raman modes. A ferroelectric to paraelectric phase transition has been observed both by Raman spectroscopy and SHG at 20.8 GPa. Contrary to LiNbO3, the ferroelectric soft mode of ZnTiO3 has been found to be the A1(2) and not the A1(1) mode. The calculated eigenvectors show that the A1(2) mode of ferroelectric ZnTiO3 is an antiphase vibration of the Ti atom against the oxygen framework, similar to the soft modes observed in ferroelectric perovskites. The SHG signal of ZnTiO3 has been found to be independent of the grain size below the phase transition, indicating that ZnTiO3 is a phase-matchable compound
Transcriptomic responses to predator kairomones in embryos of the aquatic snail Radix balthica
The ability of organisms to respond to predation threat by exhibiting induced defenses is well documented, but studies on the potential mechanistic basis for such responses are scarce. Here, we examine the transcriptomic response to predator kairomones of two functionally distinct developmental stages in embryos of the aquatic snail Radix balthica: E8âthe stage at which a rangeâfinding trial indicated that kairomoneâinduced accelerated growth and development first occurred; and E9âthe stage at which embryos switched from ciliaryâ to crawlingâdriven locomotion. We tested whether expression profiles were influenced by kairomones and whether this influence varied between stages. We also identified potential candidate genes for investigating mechanisms underpinning induced responses. There were 6,741 differentially expressed transcripts between developmental stages, compared to just five in response to predator kairomones. However, on examination of functional enrichment in the transcripts responding to predator kairomones and adopting a less stringent significance threshold, 206 transcripts were identified relating to muscle function, growth, and development, with this response being greater at the later E9 stage. Furthermore, these transcripts included putative annotations for genes identified as responding to predator kairomones in other taxa, including C1q, lectin, and actin domains. Globally, transcript expression appeared reduced in response to predator kairomones and we hypothesize that this might be a result of metabolic suppression, as has been reported in other taxa in response to predation threat
The nuanced nature of work quality : evidence from rural Newfoundland and Ireland
This article explores the relationship between job and work quality and argues that while it is important to examine job quality, to understand workersâ experiences fully, the focus should be on the broader concept of work quality, which places the job against its wider socio-economic context. Based on the experiences of 88 rural workers gathered via interviews in Newfoundland and Ireland, it appears that the same or similar jobs can be regarded very differently depending upon the context in which they are embedded, as people at different locations and/or stages of life have an individual set of aspirations, expectations and life experiences. The study found that the factors that affect work quality are moulded by broader aspects of life â family, friends, community, lifestyle and past experiences â that shape an individual
Comparing biofilm models for a single species biofilm system
Abstract A benchmark problem was defined to evaluate the performance of different mathematical biofilm models. The biofilm consisted of heterotrophic bacteria degrading organic substrate and oxygen. Mathematical models tested ranged from simple analytical to multidimensional numerical models. For simple and more or less flat biofilms it was shown that analytical biofilm models provide very similar results compared to more complex numerical solutions. When considering a heterogeneous biofilm morphology it was shown that the effect of an increased external mass transfer resistance was much more significant compared to the effect of an increased surface area inside the biofilm
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