Mecánica de daño continuo

En esta monografía se intenta presentar un marco teórico general que permita analizar la gran cantidad de modelos de daño continuo existentes, no sólo desde el punto de vista de su formulación sino también teniendo en cuenta su capacidad para reproducir las evidencias experimentales correspondientes a un amplio rango de materiales y su implementación numérica en códigos de elementos finitos. La monografía se restringe al tratamiento del daño en pequeñas deformaciones y dentro del marco de la Mecánica de Medios Continuos

Experimental and numerical analysis of blast response of High Strength Fiber Reinforced Concrete slabs

High Strength Fiber Reinforced Concrete (HSFRC) presents great advantages when compared with conventional concrete under static loads and thus, it constitutes a promising material to withstand extreme loads. The experimental results of blast tests performed on HSFRC slabs including different types of hooked end steel fibers are presented and numerically analyzed in this paper. The numerical simulation was able to reproduce the experimental results and it confirms that for the same fiber content, shorter fibers provide greater blast resistance, showing smaller craters and spalling at the back face.Facultad de Ingenierí

Efficacy and safety of extracranial vein angioplasty in multiple sclerosis: A randomized clinical trial

Importance: Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by restricted venous outflow from the brain and spinal cord. Whether this condition is associated with multiple sclerosis (MS) and whether venous percutaneous transluminal angioplasty (PTA) is beneficial in persons with MS and CCSVI is controversial. Objective: To determine the efficacy and safety of venous PTA in patients with MS and CCSVI. Design, Setting, and Participants: We analyzed 177 patients with relapsing-remitting MS; 62 were ineligible, including 47 (26.6%) who did not have CCSVI on color Doppler ultrasonography screening. A total of 115 patients were recruited in the study timeframe. All patients underwent a randomized, double-blind, sham-controlled, parallel-group trial in 6MS centers in Italy. The trial began in August 2012 and concluded in March 2016; data were analyzed from April 2016 to September 2016. The analysis was intention to treat. Interventions: Patients were randomly allocated (2:1) to either venous PTA or catheter venography without venous angioplasty (sham). Main Outcomes and Measures: Two primary end pointswere assessed at 12 months: (1) a composite functional measure (ie, walking control, balance, manual dexterity, postvoid residual urine volume, and visual acuity) and (2) a measure of new combined brain lesions on magnetic resonance imaging, including the proportion of lesion-free patients. Combined lesions included T1 gadolinium-enhancing lesions plus new or enlarged T2 lesions. Results: Of the included 115 patients with relapsing-remitting MS, 76 were allocated to the PTA group (45 female [59%]; mean [SD] age, 40.0 [10.3] years) and 39 to the sham group (29 female [74%]; mean [SD] age, 37.5 [10.6] years); 112 (97.4%) completed follow-up. No serious adverse events occurred. Flow restoration was achieved in 38 of 71 patients (54%) in the PTA group. The functional composite measure did not differ between the PTA and sham groups (41.7%vs 48.7%; odds ratio, 0.75; 95%CI, 0.34-1.68; P = .49). The mean (SD) number of combined lesions on magnetic resonance imaging at 6 to 12 months were 0.47 (1.19) in the PTA group vs 1.27 (2.65) in the sham group (mean ratio, 0.37; 95%CI, 0.15-0.91; P = .03: adjusted P = .09) and were 1.40 (4.21) in the PTA group vs 1.95 (3.73) in the sham group at 0 to 12 months (mean ratio, 0.72; 95%CI, 0.32-1.63; P = .45; adjusted P = .45). At follow-up after 6 to 12 months, 58 of 70 patients (83%) in the PTA group and 22 of 33 (67%) in the sham group were free of new lesions on magnetic resonance imaging (odds ratio, 2.64; 95%CI, 1.11-6.28; P = .03; adjusted P = .09). At 0 to 12 months, 46 of 73 patients (63.0%) in the PTA group and 18 of 37 (49%) in the sham group were free of new lesions on magnetic resonance imaging (odds ratio, 1.80; 95%CI, 0.81-4.01; P = .15; adjusted P = .30). Conclusion and Relevance: Venous PTA has proven to be a safe but largely ineffective technique; the treatment cannot be recommended in patients with MS

Current clinical applications of spectral tissue Doppler echocardiography (E/E' ratio) as a noninvasive surrogate for left ventricular diastolic pressures in the diagnosis of heart failure with preserved left ventricular systolic function

Congestive heart failure with preserved left ventricular systolic function has emerged as a growing epidemic medical syndrome in developed countries, which is characterized by high morbidity and mortality rates. Rapid and accurate diagnosis of this condition is essential for optimizing the therapeutic management. The diagnosis of congestive heart failure is challenging in patients presenting without obvious left ventricular systolic dysfunction and additional diagnostic information is most commonly required in this setting. Comprehensive Doppler echocardiography is the single most useful diagnostic test recommended by the ESC and ACC/AHA guidelines for assessing left ventricular ejection fraction and cardiac abnormalities in patients with suspected congestive heart failure, and non-invasively determined basal or exercise-induced pulmonary capillary hypertension is likely to become a hallmark of congestive heart failure in symptomatic patients with preserved left ventricular systolic function. The present review will focus on the current clinical applications of spectral tissue Doppler echocardiography used as a reliable noninvasive surrogate for left ventricular diastolic pressures at rest as well as during exercise in the diagnosis of heart failure with preserved left ventricular systolic function. Chronic congestive heart failure, a disease of exercise, and acute heart failure syndromes are characterized by specific pathophysiologic and diagnostic issues, and these two clinical presentations will be discussed separately

Modelo elastoplástico para materiales ortótropos

A general orthotropic model adequate for the analysis of complex anisotropic materials like masonry is presented. The model takes into account the differences between strength in the principal directions of anisotropy and how these differences vary with the type of process, i.e., tension, compression or any other combination of stress. In this way a general type of initial anisotropy can be defined. The model can also take into account the evolution of anisotropy during the elastoplastic process. The proposed model comes from a generalisation of classical isotropic theory of plasticity and assumes the existence of two spaces: a real anisotropic space and a fictitious isotropic space. The stress tensors in both spaces are related through a transformation tensor that takes into account the anisotropy and depends on the stress state. The problem is solved in the fictitious isotropic space. This allows to use well known yield functions developed for standard isotropic materials

Nonlinear structural dynamics

When solving dynamic problems, it is necessary to define in some way the damping of the structure. Generally, a damping term that depends on the velocities is incorporated directly into the dynamic equilibrium equation. To do this, we define a structural damping matrix, such as Rayleigh's, which is quite difficult to estimate. Once the damping has been defined, the problem is solved as a linear elastic one, what enters in contradiction with the fact that a dissipative phenomenon is being treated. In this chapter, an alternative with greater conceptual basis is described, which considers the structural damping based on a viscoelastic constitutive models in which the stress depends in some way on the strain velocity. In this way, the term of structural damping arises directly in the dynamic equilibrium equation, where the properties of the materials can be determined through simple laboratory tests