Fractional chemotaxis diffusion equations

We introduce mesoscopic and macroscopic model equations of chemotaxis with anomalous subdiffusion for modeling chemically directed transport of biological organisms in changing chemical environments with diffusion hindered by traps or macromolecular crowding. The mesoscopic models are formulated using continuous time random walk equations and the macroscopic models are formulated with fractional order differential equations. Different models are proposed depending on the timing of the chemotactic forcing. Generalizations of the models to include linear reaction dynamics are also derived. Finally a Monte Carlo method for simulating anomalous subdiffusion with chemotaxis is introduced and simulation results are compared with numerical solutions of the model equations. The model equations developed here could be used to replace Keller-Segel type equations in biological systems with transport hindered by traps, macromolecular crowding or other obstacles

Anomalous subdiffusion with multispecies linear reaction dynamics

We have introduced a set of coupled fractional reaction-diffusion equations to model a multispecies system undergoing anomalous subdiffusion with linear reaction dynamics. The model equations are derived from a mesoscopic continuous time random walk formulation of anomalously diffusing species with linear mean field reaction kinetics. The effect of reactions is manifest in reaction modified spatiotemporal diffusion operators as well as in additive mean field reaction terms. One consequence of the nonseparability of reaction and subdiffusion terms is that the governing evolution equation for the concentration of one particular species may include both reactive and diffusive contributions from other species. The general solution is derived for the multispecies system and some particular special cases involving both irreversible and reversible reaction dynamics are analyzed in detail. We have carried out Monte Carlo simulations corresponding to these special cases and we find excellent agreement with theory

Fractional Chemotaxis Diffusion Equations

We introduce mesoscopic and macroscopic model equations of chemotaxis with anomalous subdiffusion for modelling chemically directed transport of biological organisms in changing chemical environments with diffusion hindered by traps or macro-molecular crowding. The mesoscopic models are formulated using Continuous Time Random Walk master equations and the macroscopic models are formulated with fractional order differential equations. Different models are proposed depending on the timing of the chemotactic forcing. Generalizations of the models to include linear reaction dynamics are also derived. Finally a Monte Carlo method for simulating anomalous subdiffusion with chemotaxis is introduced and simulation results are compared with numerical solutions of the model equations. The model equations developed here could be used to replace Keller-Segel type equations in biological systems with transport hindered by traps, macro-molecular crowding or other obstacles.Comment: 25page

Automorphic properties of low energy string amplitudes in various dimensions

This paper explores the moduli-dependent coefficients of higher derivative interactions that appear in the low-energy expansion of the four-graviton amplitude of maximally supersymmetric string theory compactified on a d-torus. These automorphic functions are determined for terms up to order D^6R^4 and various values of d by imposing a variety of consistency conditions. They satisfy Laplace eigenvalue equations with or without source terms, whose solutions are given in terms of Eisenstein series, or more general automorphic functions, for certain parabolic subgroups of the relevant U-duality groups. The ultraviolet divergences of the corresponding supergravity field theory limits are encoded in various logarithms, although the string theory expressions are finite. This analysis includes intriguing representations of SL(d) and SO(d,d) Eisenstein series in terms of toroidally compactified one and two-loop string and supergravity amplitudes.Comment: 80 pages. 1 figure. v2:Typos corrected, footnotes amended and small clarifications. v3: minor corrections. Version to appear in Phys Rev

Fractional Fokker-Planck Equations for Subdiffusion with Space-and-Time-Dependent Forces

We have derived a fractional Fokker-Planck equation for subdiffusion in a general space-and- time-dependent force field from power law waiting time continuous time random walks biased by Boltzmann weights. The governing equation is derived from a generalized master equation and is shown to be equivalent to a subordinated stochastic Langevin equation.Comment: 5 page

Evaluation of a disease specific rheumatoid arthritis self-management education program, a single group repeated measures study

Background: Rheumatoid Arthritis is a progressive and disabling disease, predicted to increase in prevalence over the next 50 years. Self-management is acknowledged as an integral part in the management of chronic disease. The rheumatoid arthritis specific self-management program delivered by health professionals was developed by Arthritis Western Australia in 2006. The purpose of this study was to determine whether this program would achieve early benefits in health related outcomes, and whether these improvements would be maintained for 12 months. Methods: Individuals with rheumatoid arthritis were referred from rheumatologists. Participants with co-existing inflammatory musculoskeletal conditions were excluded. All participants completed a 6-week program. Assessments occurred at baseline (8 weeks prior to intervention), pre-intervention, post-intervention, and 6 and 12 month follow ups. Outcomes measured included pain and fatigue (numerical rating scale, 0-10), depression and anxiety (hospital anxiety and depression questionnaire), health distress, and quality of life (SF-36 version 2). Results: There were significant improvements in mean [SD] fatigue (5.7 [2.4] to 5.1 [2.6]), depression (6.3 [4.3] to 5.6 [3.9]) and SF-36 mental health (44.5 [11.1] to 46.5 [9.5]) immediately following intervention, with long term benefits for depression (6.3 [4.3] to 4.9 [3.9]), and SF-36 subscales mental health (44.5 [11.1] to 47.8 [10.9]), role emotional (41.5 [13.2] to 46.5 [11.8]), role physical (35.0 [11.0] to 40.2 [12.1]) and physical function (34.8 [11.5] to 38.6 [10.7]). Conclusion: Participants in the program recorded significant improvements in depression and mental health post-intervention, which were maintained to 12 months follow up

The Tails of the Crossing Probability

The scaling of the tails of the probability of a system to percolate only in the horizontal direction $\pi_{hs}$ was investigated numerically for correlated site-bond percolation model for $q=1,2,3,4$.We have to demonstrate that the tails of the crossing probability far from the critical point have shape $\pi_{hs}(p) \simeq D \exp(c L[p-p_{c}]^{\nu})$ where $\nu$ is the correlation length index, $p=1-\exp(-\beta)$ is the probability of a bond to be closed. At criticality we observe crossover to another scaling $\pi_{hs}(p) \simeq A \exp (-b {L [p-p_{c}]^{\nu}}^{z})$. Here $z$ is a scaling index describing the central part of the crossing probability.Comment: 20 pages, 7 figures, v3:one fitting procedure is changed, grammatical change

Critical Percolation in Finite Geometries

The methods of conformal field theory are used to compute the crossing probabilities between segments of the boundary of a compact two-dimensional region at the percolation threshold. These probabilities are shown to be invariant not only under changes of scale, but also under mappings of the region which are conformal in the interior and continuous on the boundary. This is a larger invariance than that expected for generic critical systems. Specific predictions are presented for the crossing probability between opposite sides of a rectangle, and are compared with recent numerical work. The agreement is excellent.Comment: 10 page

On indecomposable modules over the Virasoro algebra

It is proved that an indecomposable Harish-Chandra module over the Virasoro algebra must be (i) a uniformly bounded module, or (ii) a module in Category $\cal O$, or (iii) a module in Category ${\cal O}^-$, or (iv) a module which contains the trivial module as one of its composition factors.Comment: 5 pages, Latex, to appear in Science in China

Statistical properties of the low-temperature conductance peak-heights for Corbino discs in the quantum Hall regime

A recent theory has provided a possible explanation for the ``non-universal scaling'' of the low-temperature conductance (and conductivity) peak-heights of two-dimensional electron systems in the integer and fractional quantum Hall regimes. This explanation is based on the hypothesis that samples which show this behavior contain density inhomogeneities. Theory then relates the non-universal conductance peak-heights to the ``number of alternating percolation clusters'' of a continuum percolation model defined on the spatially-varying local carrier density. We discuss the statistical properties of the number of alternating percolation clusters for Corbino disc samples characterized by random density fluctuations which have a correlation length small compared to the sample size. This allows a determination of the statistical properties of the low-temperature conductance peak-heights of such samples. We focus on a range of filling fraction at the center of the plateau transition for which the percolation model may be considered to be critical. We appeal to conformal invariance of critical percolation and argue that the properties of interest are directly related to the corresponding quantities calculated numerically for bond-percolation on a cylinder. Our results allow a lower bound to be placed on the non-universal conductance peak-heights, and we compare these results with recent experimental measurements.Comment: 7 pages, 4 postscript figures included. Revtex with epsf.tex and multicol.sty. The revised version contains some additional discussion of the theory and slightly improved numerical result