Dynamic Server Allocation over Time Varying Channels with Switchover Delay

We consider a dynamic server allocation problem over parallel queues with randomly varying connectivity and server switchover delay between the queues. At each time slot the server decides either to stay with the current queue or switch to another queue based on the current connectivity and the queue length information. Switchover delay occurs in many telecommunications applications and is a new modeling component of this problem that has not been previously addressed. We show that the simultaneous presence of randomly varying connectivity and switchover delay changes the system stability region and the structure of optimal policies. In the first part of the paper, we consider a system of two parallel queues, and develop a novel approach to explicitly characterize the stability region of the system using state-action frequencies which are stationary solutions to a Markov Decision Process (MDP) formulation. We then develop a frame-based dynamic control (FBDC) policy, based on the state-action frequencies, and show that it is throughput-optimal asymptotically in the frame length. The FBDC policy is applicable to a broad class of network control systems and provides a new framework for developing throughput-optimal network control policies using state-action frequencies. Furthermore, we develop simple Myopic policies that provably achieve more than 90% of the stability region. In the second part of the paper, we extend our results to systems with an arbitrary but finite number of queues.Comment: 38 Pages, 18 figures. arXiv admin note: substantial text overlap with arXiv:1008.234

Analysis of finite arrays of circumferentially oriented printed dipoles on electrically large cylinders

An efficient and accurate hybrid method of moments (MoM)/Green's function technique in the spatial domain is developed for the rigorous analysis of large, finite phased arrays of circumferentially oriented printed dipoles on electrically large, dielectric-coated, circular cylinders. Basic performance metrics (in the form of array current distribution, active reflection coefficient, far-field patterns, and so forth) of several arrays have been obtained and compared with similar printed arrays on grounded planar substrates. Certain discrepancies have been observed and discussed. © 2004 Wiley Periodicals, Inc

Controversy in statistical analysis of functional magnetic resonance imaging data

To test the validity of statistical methods for fMRI data analysis, Eklund et al. (1) used, for the first time, large-scale experimental data rather than simulated data. Using resting-state fMRI measurements to represent a null hypothesis of no task-induced activation, the authors compare familywise error rates for voxel-based and cluster-based inferences for both parametric and nonparametric methods. Eklund et al.’s study used three fMRI statistical analysis packages. They found that, for a target familywise error rate of 5%, the parametric methods gave invalid cluster-based inferences and conservative voxel-based inferences

A parametric analysis of finite phased arrays of printed dipoles on large circular cylinders and comparisons with the planar case

Finite phased arrays of printed dipoles on electrically large coated cylinders using spatial domain hybrid MoM/Green's function was discussed. Active reflection coefficient and input impedances of the dipoles were calculated and compared with planar counterparts. MoM/Green's function technique was developed to improve the efficiency and accuracy problems in the analysis of conformal arrays. The effects of curvature, dipole orientation and changes in the array and host body parameters was observed

Scan blindness phenomenon in conformal finite phased arrays of printed dipoles

Scan blindness phenomenon for finite phased arrays of printed dipoles on material coated, electrically large circular cylinders is investigated. Effects on the scan blindness mechanism of several array and supporting structure parameters, including curvature effects, are observed and discussed. A full-wave solution, based on a hybrid method of moments/ Green's function technique in the spatial domain, is used to achieve the aforementioned goals. Numerical results show that the curvature affects the surface waves and hence the mutual coupling between array elements. As a result, the array current distribution of arrays mounted on coated cylinders are considerably different compared to similar arrays on planar platforms. Therefore, finite phased arrays of printed dipoles on coated cylinders show different behavior in terms of scan blindness phenomenon compared to their planar counterparts. Furthermore, this phenomenon is completely different for axially and circumferentially oriented printed dipoles on coated cylinders suggesting that particular element types might be important for cylindrical arrays. © 2006 IEEE

Raman enhancement on a broadband meta-surface

Plasmonic metamaterials allow confinement of light to deep subwavelength dimensions, while allowing for the tailoring of dispersion and electromagnetic mode density to enhance specific photonic properties. Optical resonances of plasmonic molecules have been extensively investigated; however, benefits of strong coupling of dimers have been overlooked. Here, we construct a plasmonic meta-surface through coupling of diatomic plasmonic molecules which contain a heavy and light meta-atom. Presence and coupling of two distinct types of localized modes in the plasmonic molecule allow formation and engineering of a rich band structure in a seemingly simple and common geometry, resulting in a broadband and quasi-omni-directional meta-surface. Surface-enhanced Raman scattering benefits from the simultaneous presence of plasmonic resonances at the excitation and scattering frequencies, and by proper design of the band structure to satisfy this condition, highly repeatable and spatially uniform Raman enhancement is demonstrated. On the basis of calculations of the field enhancement distribution within a unit cell, spatial uniformity of the enhancement at the nanoscale is discussed. Raman scattering constitutes an example of nonlinear optical processes, where the wavelength conversion during scattering may be viewed as a photonic transition between the bands of the meta-material. © 2012 American Chemical Society

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3

Seizure protein 6 (SEZ6) is required for the development and maintenance of the nervous system, is a major substrate of the protease BACE1 and is linked to Alzheimer's disease (AD) and psychiatric disorders, but its molecular functions are not well understood. Here, we demonstrate that SEZ6 controls glycosylation and cell surface localization of kainate receptors composed of GluK2/3 subunits. Loss of SEZ6 reduced surface levels of GluK2/3 in primary neurons and reduced kainate-evoked currents in CA1 pyramidal neurons in acute hippocampal slices. Mechanistically, loss of SEZ6 in vitro and in vivo prevented modification of GluK2/3 with the human natural killer-1 (HNK-1) glycan, a modulator of GluK2/3 function. SEZ6 interacted with GluK2 through its ectodomain and promoted post-endoplasmic reticulum transport of GluK2 in the secretory pathway in heterologous cells and primary neurons. Taken together, SEZ6 acts as a new trafficking factor for GluK2/3. This novel function may help to better understand the role of SEZ6 in neurologic and psychiatric diseases

Biodiversity mainstreaming for healthy & sustainable food systems: A toolkit to support incorporating biodiversity into policies and programmes

The Biodiversity for Food and Nutrition Initiative (BFN Project) uses indigenous food biodiversity as a lens to address malnutrition, farmer livelihood resilience, and sustainability. Since 2012, the initiative has pioneered a cross-sectoral, partner-based approach to document and share information on 195 nutrient-rich, locally-adapted species ranging from African leafy vegetables to Amazonian fruits. Spearheaded by governments and research organizations in Brazil, Kenya, Sri Lanka, and Turkey, BFN developed a three-pronged methodology to ensure the conservation, revival, and promotion of these underutilised species. This toolkit is an open-access guide to mainstreaming biodiversity that draws on case studies across the four partner countries, outlining steps to 1) Provide Evidence; 2) Influence Policy, and 3) Raise Awareness. With an emphasis on both key focus areas and site-specific examples, the toolkit offers readers inspiration to adapt the work of BFN to other regions. Links to key resources collect additional information and contextualise the project methods, for example, in relation to the FAO Voluntary Guidelines for Mainstreaming Biodiversity into Policies, Programmes and National and Regional Plans on Nutrition. Focus points within the toolkit include how to make use of: National Biodiversity Strategy and Action Plans, school feeding and procurement, green employment, cultural festivals, and business cases for mainstreaming biodiversity