A High Speed Hardware Scheduler for 1000-port Optical Packet Switches to Enable Scalable Data Centers

Meeting the exponential increase in the global demand for bandwidth has become a major concern for today's data centers. The scalability of any data center is defined by the maximum capacity and port count of the switching devices it employs, limited by total pin bandwidth on current electronic switch ASICs. Optical switches can provide higher capacity and port counts, and hence, can be used to transform data center scalability. We have recently demonstrated a 1000-port star-coupler based wavelength division multiplexed (WDM) and time division multiplexed (TDM) optical switch architecture offering a bandwidth of 32 Tbit/s with the use of fast wavelength-tunable transmitters and high-sensitivity coherent receivers. However, the major challenge in deploying such an optical switch to replace current electronic switches lies in designing and implementing a scalable scheduler capable of operating on packet timescales. In this paper, we present a pipelined and highly parallel electronic scheduler that configures the high-radix (1000-port) optical packet switch. The scheduler can process requests from 1000 nodes and allocate timeslots across 320 wavelength channels and 4000 wavelength-tunable transceivers within a time constraint of 1μs. Using the Opencell NanGate 45nm standard cell library, we show that the complete 1000-port parallel scheduler algorithm occupies a circuit area of 52.7mm2, 4-8x smaller than that of a high-performance switch ASIC, with a clock period of less than 8ns, enabling 138 scheduling iterations to be performed in 1μs. The performance of the scheduling algorithm is evaluated in comparison to maximal matching from graph theory and conventional software-based wavelength allocation heuristics. The parallel hardware scheduler is shown to achieve similar matching performance and network throughput while being orders of magnitude faster

Expression of the tobacco β- 1,3-glucanase gene, PR-2d, following induction of SAR with \u3ci\u3ePeronospora tabacina\u3c/i\u3e

Systemic acquired resistance (SAR) is induced following inoculation of Peronospora tabacina sporangia into the stems of Nicotiana tabacum plants highly susceptible to the pathogen. Previous results have shown that accumulation of acidic P-1,3-glucanases (PR-2\u27s) following induction of SAR by P. tabacina may contribute to resistance to P. tabacina. We showed that up-regulation of the PR-2 gene, PR-2d, following stem inoculation with P. tabacina, is associated with SAR. Studies using plants transformed with GUS constructs containing the full length promoter from PR-2d or promoter deletions, provided evidence that a previously characterized regulatory element that is involved in response to salicylic acid (SA), may be involved in regulation of PR-2d following induction of SAR with P. tabacina. This work provides evidence that regulation of PR-2 genes during P. tabacina-induced SAR may be similar to regulation of these genes during infection of N-gene tobacco by TMV or following exogenous application of SA, and provides further support for the role of SA in regulation of genes during P. tabacina-induced SAR

Expression of the tobacco β- 1,3-glucanase gene, PR-2d, following induction of SAR with \u3ci\u3ePeronospora tabacina\u3c/i\u3e

Systemic acquired resistance (SAR) is induced following inoculation of Peronospora tabacina sporangia into the stems of Nicotiana tabacum plants highly susceptible to the pathogen. Previous results have shown that accumulation of acidic P-1,3-glucanases (PR-2\u27s) following induction of SAR by P. tabacina may contribute to resistance to P. tabacina. We showed that up-regulation of the PR-2 gene, PR-2d, following stem inoculation with P. tabacina, is associated with SAR. Studies using plants transformed with GUS constructs containing the full length promoter from PR-2d or promoter deletions, provided evidence that a previously characterized regulatory element that is involved in response to salicylic acid (SA), may be involved in regulation of PR-2d following induction of SAR with P. tabacina. This work provides evidence that regulation of PR-2 genes during P. tabacina-induced SAR may be similar to regulation of these genes during infection of N-gene tobacco by TMV or following exogenous application of SA, and provides further support for the role of SA in regulation of genes during P. tabacina-induced SAR

Fast and Uniform Optically-Switched Data Centre Networks Enabled by Amplitude Caching

We propose amplitude caching to optically equalise burst mode traffic without delay stages. Through a fast, optically-switched system prototype, we demonstrate burst-mode penalties can be mitigated to within 0.4 dB at the KR4 HD-FEC level

Perceived Effectiveness, Cost, and Availability of Patient Education Methods and Materials

To determine the efficacy of and need for patient education methods and media, a needs assessment was sent to 816 members of the American Association of Diabetes Educators. Respondents (n=325, 40%) included 62% RNs, 36% RDs, 1% other; 62% CDEs. Their mean number of years experience in diabetes education was 8.5, and 99% routinely provided patient education. Respondents indicated that videotapes and slide tapes were the most educationally effective media and books and audiotapes were the least effective. Booklets and videotapes were the most cost-effective and computer-assisted instruction the least effective. While respondents perceived one-to-one counseling, skills training, and diabetes content sessions to be the three most educationally effective methods, support groups and large and small discussion groups were seen as the three most cost-effective educational methods. Among nine potential barriers to quality patient education listed, educators rated lack of third-party reimbursement as a major barrier most frequently and national availability of quality education materials as a barrier least frequently.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68739/2/10.1177_014572179201800207.pd

Student experiences of practical activities during the COVID-19 pandemic

During the COVID-19 pandemic practical activities for undergraduate students have been severely disrupted. Activities in the field of computing, control, electrical and electronic engineering at the University of Sheffield have been taught during the autumn term of 2020/2021 academic year through socially distanced in-lab sessions, remote access to in-lab equipment, take-home kits, and other online methods. Students were asked to leave feedback for each activity using an anonymous online questionnaire, designed to capture their perceptions on their learning experience. Based on the responses received, a number of recommendations have been formulated to help practical educators make decisions on the modes of delivery of certain activities and for certain student cohorts, when pivoting to increased distance learning. Students indicated they would prefer to conduct some activities using take-home kits in the future, paving the way for beneficial long-term changes to the delivery of some practical activities beyond the times of the pandemic

Healthcare Game Design: Behavioral Modeling of Serious Gaming Design for Children with Chronic Diseases

This article introduces the design principles of serious games for chronic patients based on behavioral models. First, key features of the targeted chronic condition (Diabetes) are explained. Then, the role of psychological behavioral models in the management of chronic conditions is covered. After a short review of the existing health focused games, two recent health games that are developed based on behavioral models are overviewed in more detail. Furthermore, design principles and usability issues regarding the creation of these health games are discussed. Finally, the authors conclude that designing healthcare games based on behavioral models can increase the usability of the game in order to improve the effectiveness of the game’s desired healthcare outcomes

Web-based guided insulin self-titration in patients with type 2 diabetes: the Di@log study. Design of a cluster randomised controlled trial [TC1316]

<p>Abstract</p> <p>Background</p> <p>Many patients with type 2 diabetes (T2DM) are not able to reach the glycaemic target level of HbA1c < 7.0%, and therefore are at increased risk of developing severe complications. Transition to insulin therapy is one of the obstacles in diabetes management, because of barriers of both patient and health care providers. Patient empowerment, a patient-centred approach, is vital for improving diabetes management. We developed a web-based self-management programme for insulin titration in T2DM patients. The aim of our study is to investigate if this internet programme helps to improve glycaemic control more effectively than usual care.</p> <p>Methods/Design</p> <p>T2DM patients (n = 248), aged 35–75 years, with an HbA1c ≥ 7.0%, eligible for treatment with insulin and able to use the internet will be selected from general practices in two different regions in the Netherlands. Cluster randomisation will be performed at the level of general practices. Patients in the intervention group will use a self-developed internet programme to assist them in self-titrating insulin. The control group will receive usual care.</p> <p>Primary outcome is the difference in change in HbA1c between intervention and control group. Secondary outcome measures are quality of life, treatment satisfaction, diabetes self-efficacy and frequency of hypoglycaemic episodes. Results will be analysed according to the intention-to-treat principle.</p> <p>Discussion</p> <p>An internet intervention supporting self-titration of insulin therapy in T2DM patients is an innovative patient-centred intervention. The programme provides guided self-monitoring and evaluation of health and self-care behaviours through tailored feedback on input of glucose values. This is expected to result in a better performance of self-titration of insulin and consequently in the improvement of glycaemic control. The patient will be enabled to 'discover and use his or her own ability to gain mastery over his/her diabetes' and therefore patient empowerment will increase. Based on the self-regulation theory of Leventhal, we hypothesize that additional benefits will be achieved in terms of increases in treatment satisfaction, quality of life and self-efficacy.</p> <p>Trial registration</p> <p>Dutch Trial Register TC1316.</p