17 research outputs found

    Nanoindentation of ZA27 alloy based nanocomposites reinforced with Al2O3 particles

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    Nanoindentation has been widely used for material mechanical characterization. In this study, nanocomposite of ZA27 alloy matrix reinforced with different volume fractions of nanometric Al2O3 ceramic particles ranging from 0 to 5 %, were produces using compocasting technique. Nanoindentation tests were performed using Berkovich three sided diamond pyramid, with maximum load of 100 mN and maximum load holding time of 15 s. Indentation imprints were investigated using optical and atomic force microscopy (AFM). Average particle size was 20-30 nm. Nanoindentation tests showed that nanocomposites have higher values of hardness and lower values of elastic modulus in comparison to the ZA27 matrix alloy. Obtained results have different values in comparison to the theoretical investigations.Publishe

    Molecular Effects of Doxycycline Treatment on Pterygium as Revealed by Massive Transcriptome Sequencing

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    Pterygium is a lesion of the eye surface which involves cell proliferation, migration, angiogenesis, fibrosis, and extracellular matrix remodelling. Surgery is the only approved method to treat this disorder, but high recurrence rates are common. Recently, it has been shown in a mouse model that treatment with doxycycline resulted in reduction of the pterygium lesions. Here we study the mechanism(s) of action by which doxycycline achieves these results, using massive sequencing techniques. Surgically removed pterygia from 10 consecutive patients were set in short term culture and exposed to 0 (control), 50, 200, and 500 µg/ml doxycycline for 24 h, their mRNA was purified, reverse transcribed and sequenced through Illumina’s massive sequencing protocols. Acquired data were subjected to quantile normalization and analyzed using cytoscape plugin software to explore the pathways involved. False discovery rate (FDR) methods were used to identify 332 genes which modified their expression in a dose-dependent manner upon exposure to doxycycline. The more represented cellular pathways included all mitochondrial genes, the endoplasmic reticulum stress response, integrins and extracellular matrix components, and growth factors. A high correlation was obtained when comparing ultrasequencing data with qRT-PCR and ELISA results

    Complex geophysical investigations for geothermal purposes

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    Nano identification and tribo testing of explosive welding copper/brass

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    Bimetallic materials are construction materials that are increasingly used in many industries: in the graphic industry, tobacco processing industry for various cutting knives, in the chemical industry for various plants and vessels, food industry, military industry, etc. In the production of ships, their use becomes dominant, primarily as a combination of cheap construction materials highly resistant to corrosion, at a price closer to construction materials. The appearance of plating with the help of explosion energy has significantly increased the range and quality of available multilayer metals. Although stainless steels and aluminum are the most commonly used material for bimetallic and clad materials, materials such as titanium, zirconium or tantalum are increasingly used. The paper analyzes the process of explosion welding and the results of exploration of the explosion of a welded joint of copper and brass. The microhardness of the material in the welded joint, tribological characteristics and scratch test joint were analyzed

    Static friction at high contact temperatures and low contact pressure

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    The problem of measuring static friction at high temperatures and low contact pressures is theoretically analyzed, as well as the instruments for the accurate determination of the coefficient of static friction at high temperatures for contact pairs made of steel and bronze. The results of experimental investigation show that at low contact pressure and temperature above 120°C coefficient of static friction dramatically increases. This increase in the coefficient of friction can be of great practical value with regard to the load capacity of contacts where external forces are balanced with friction forces. © 2013 Allerton Press, Inc

    Modeling and Prediction of Surface Roughness in the End Milling Process using Multiple Regression Analysis and Artificial Neural Network

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    In recent years, trends have been towards modeling machine processing using artificial intelligence. Artificial neural network (ANN) and multiple regression analysis are methods used to model and optimize the performance of manufacturing technologies. ANN and multiple regression analysis show high reliability in the prediction and optimization of machining processes. In this paper, machining parameters such as spindle speed, feed rate and depth of cut were used in end milling process to minimize surface roughness. The influence of the parameters on the surface roughness was investigated using an artificial neural network and multiple regression analysis, and results are compared with the measured results

    INFLUENCE OF VANADIUM CONTENT ON THE TRIBOLOGICAL BEHAVIOUR OF X140CrMol2-l AIR-HARDENING STEEL

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    The paper presents experimental testing of wear resistance of steel samples from the same groups of steel. Test results were recorded and presented in the form of diagrams showing the wear resistance of the tested materials in different sliding conditions. The tested steels have high carbon content; the addition of chromium and molybdenum results in the high hardness and low impact toughness of the steels. The addition of vanadium changes the microstructure when the metal grain becomes smaller and the whole structure is martensitic, with chromium and vanadium carbides in the metal matrix. A change in the microstructure causes a change in mechanical properties. The obtained results showed that the addition of vanadium increases impact toughness. However, it is not known how it affects wear resistance and hardness. This type of steel belongs to a new group of steels resistant to wear. A change in the vanadium content causes a decrease in the hardness and wear resistance of the steel and an increase in its impact toughness
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