Cannabis use and other illicit drug use: Do subjective experiences during first cannabis use increase the probability of using illicit drug use?

Background and aims: Few studies have examined whether subjective experiences during first cannabis use are related to other illicit drug (OID) use. This study investigated this topic. Methods: Baseline data from a representative sample of young Swiss men was obtained from an ongoing Cohort Study on Substance Use Risk Factors (N ¼ 5753). Logistic regressions were performed to examine the relationships between cannabis use and of subjective experiences during first cannabis use with 15 OID. Results: Positive experiences increased the likelihood of using hallucinogens (hallucinogens, salvia divinorum, spice; p50.015), stimulants (speed, ecstasy, cocaine, amphetamines/methamphetamines; p50.006) and also poppers, research chemicals, GHB/GBL, and crystal meth (p50.049). Sniffed drugs (poppers, solvents for sniffing) and ''hard'' drugs (heroin, ketamine, research chemicals, GHB/GBL and crystal meth) were more likely to be used by participants who experienced negative feelings on first use of cannabis (p50.034). Conclusion: Subjective feelings seemed to amplify the association of cannabis with OID. The risk increased for drugs with effects resembling feelings experienced on first cannabis use. Negative experiences should also be a concern, as they were associated with increased risk of using the ''hardest'' illicit drugs

Patterns and transitions in substance use among young Swiss men: a latent transition analysis approach

This study investigates the potential stages of drug use. Data from the longitudinal Cohort Study on Substance Use Risk Factors were used (N = 5,116). Drug use (alcohol, tobacco, and 16 illicit drugs) over the previous 12 months was assessed at two time points. Patterns and trajectories of drug use were studied using latent transition analysis (LTA). This study's substantive contributions are twofold. First, the pattern of drug use displayed the well-known sequence of drug involvement (licit drugs to cannabis to other illicit drugs), but with an added distinction between two kinds of illicit drugs ("middle-stage" drugs: uppers, hallucinogens, inhaled drugs; and "final-stage" drugs: heroin, ketamine, GHB/GBL, research chemicals, crystal meth, and spice). Second, subgroup membership was stable over time, as the most likely transition was remaining in the same latent class

Performance and Economic Analysis of Distributed Power Electronics in Photovoltaic Systems

Distributed electronics like micro-inverters and DC-DC converters can help recover mismatch and shading losses in photovoltaic (PV) systems. Under partially shaded conditions, the use of distributed electronics can recover between 15-40% of annual performance loss or more, depending on the system configuration and type of device used. Additional value-added features may also increase the benefit of using per-panel distributed electronics, including increased safety, reduced system design constraints and added monitoring and diagnostics. The economics of these devices will also become more favorable as production volume increases, and integration within the solar panel?s junction box reduces part count and installation time. Some potential liabilities of per-panel devices include increased PV system cost, additional points of failure, and an insertion loss that may or may not offset performance gains under particular mismatch conditions

The Swiss cohort study on substance use risk factors : findings of two waves

Aim: To summarize published findings in peer-reviewed journals of the first two waves of the Swiss Cohort Study on Substance Use Risk Factors (C-SURF), a longitudinal study assessing risk and protective factors of 5,987 young men during the phase of emerging adulthood (20 years at baseline, followed-up 15 months later). Methods: Included were 33 studies published until November 2014 focusing on substance use. Results: Substance use in early adulthood is a prevalent and stable behavior. The 12-month prevalence of nonmedical use of prescription drugs (10.6%) lies between that of cannabis (36.4%) and other illicit drugs such as ecstasy (3.7%) and cocaine (3.2%). Although peer pressure in the form of misconduct is associated with increased substance use, other aspects such as peer involvement in social activities may have beneficial effects. Regular sport activities are associated with reduced substance use, with the exception of alcohol use. Young men are susceptible to structural conditions such as the price of alcohol beverages or the density of on-premise alcohol outlets. Particularly alcohol use in public settings such as bars, discos or in parks (compared with private settings such as the home) is associated with alcohol-related harm, including injuries or violence. Being a single parent versus nuclear family has no effect on alcohol use, but active parenting does. Besides parenting, religiousness is an important protective factor for both legal and illegal substance use. Merely informing young men about the risks of substance use may not be an effective preventive measure. At-risk users of licit and illicit substances are more health literate, e. g., for example, they seek out more information on the internet than non-at-risk-users or abstainers. Discussion: There are a number of risk and protective substance use factors, but their associations with substance use do not necessarily agree with those found outside Europe. In the United States, for example, heavy alcohol use in this age group commonly takes place in private settings, whereas in Switzerland it more often takes place in public settings. Other behaviors, such as the nonmedical use of prescription drugs, appear to be similar to those found overseas, which may show the need for targeted preventive actions. C-SURF findings point to the necessity of establishing European studies to identify factors for designing specific preventive actions

Towards a science of climate and energy choices

The linked problems of energy sustainability and climate change are among the most complex and daunting facing humanity at the start of the twenty-first century. This joint Nature Energy and Nature Climate Change Collection illustrates how understanding and addressing these problems will require an integrated science of coupled human and natural systems; including technological systems, but also extending well beyond the domain of engineering or even economics. It demonstrates the value of replacing the stylized assumptions about human behaviour that are common in policy analysis, with ones based on data-driven science. We draw from and engage articles in the Collection to identify key contributions to understanding non-technological factors connecting economic activity and greenhouse gas emissions, describe a multi-dimensional space of human action on climate and energy issues, and illustrate key themes, dimensions and contributions towards fundamental understanding and informed decision making

The atmosphere and architecture of WASP-189 b probed by its CHEOPS phase curve

Context. Gas giants orbiting close to hot and massive early-type stars can reach dayside temperatures that are comparable to those of the coldest stars. These ‘ultra-hot Jupiters’ have atmospheres made of ions and atomic species from molecular dissociation and feature strong day-to-night temperature gradients. Photometric observations at different orbital phases provide insights on the planet’s atmospheric properties. Aims. We aim to analyse the photometric observations of WASP-189 acquired with the Characterising Exoplanet Satellite (CHEOPS) to derive constraints on the system architecture and the planetary atmosphere. Methods. We implemented a light-curve model suited for an asymmetric transit shape caused by the gravity-darkened photosphere of the fast-rotating host star. We also modelled the reflective and thermal components of the planetary flux, the effect of stellar oblateness and light-travel time on transit-eclipse timings, the stellar activity, and CHEOPS systematics. Results. From the asymmetric transit, we measure the size of the ultra-hot Jupiter WASP-189 b, Rp = 1.600−0.016+0.017 RJ, with a precision of 1%, and the true orbital obliquity of the planetary system, Ψp = 89.6 ± 1.2deg (polar orbit). We detect no significant hotspot offset from the phase curve and obtain an eclipse depth of δecl = 96.5−5.0+4.5 ppm, from which we derive an upper limit on the geometric albedo: Ag < 0.48. We also find that the eclipse depth can only be explained by thermal emission alone in the case of extremely inefficient energy redistribution. Finally, we attribute the photometric variability to the stellar rotation, either through superficial inhomogeneities or resonance couplings between the convective core and the radiative envelope. Conclusions. Based on the derived system architecture, we predict the eclipse depth in the upcoming Transiting Exoplanet Survey Satellite (TESS) observations to be up to ~165 ppm. High-precision detection of the eclipse in both CHEOPS and TESS passbands might help disentangle reflective and thermal contributions. We also expect the right ascension of the ascending node of the orbit to precess due to the perturbations induced by the stellar quadrupole moment J2 (oblateness)

Enforcing Programming Guidelines with Region Types and Effects

We present in this paper a new type and effect system for Java which can be used to ensure adherence to guidelines for secure web programming. The system is based on the region and effect system by Beringer, Grabowski, and Hofmann. It improves upon it by being parametrized over an arbitrary guideline supplied in the form of a finite monoid or automaton and a type annotation or mockup code for external methods. Furthermore, we add a powerful type inference based on precise interprocedural analysis and provide an implementation in the Soot framework which has been tested on a number of benchmarks including large parts of the Stanford SecuriBench.Comment: long version of APLAS'17 pape

The atmosphere and architecture of WASP-189 b probed by its CHEOPS phase curve

Context. Gas giants orbiting close to hot and massive early-type stars can reach dayside temperatures that are comparable to those of the coldest stars. These `ultra-hot Jupiters' have atmospheres made of ions and atomic species from molecular dissociation and feature strong day-to-night temperature gradients. Photometric observations at different orbital phases provide insights on the planet's atmospheric properties. Aims: We aim to analyse the photometric observations of WASP-189 acquired with the Characterising Exoplanet Satellite (CHEOPS) to derive constraints on the system architecture and the planetary atmosphere. Methods: We implemented a light-curve model suited for an asymmetric transit shape caused by the gravity-darkened photosphere of the fast-rotating host star. We also modelled the reflective and thermal components of the planetary flux, the effect of stellar oblateness and light-travel time on transit-eclipse timings, the stellar activity, and CHEOPS systematics. Results: From the asymmetric transit, we measure the size of the ultra-hot Jupiter WASP-189 b, Rp = 1.600−0.016+0.017 RJ, with a precision of 1%, and the true orbital obliquity of the planetary system, Ψp = 89.6 ± 1.2deg (polar orbit). We detect no significant hotspot offset from the phase curve and obtain an eclipse depth of δecl = 96.5−5.0+4.5 ppm, from which we derive an upper limit on the geometric albedo: Ag < 0.48. We also find that the eclipse depth can only be explained by thermal emission alone in the case of extremely inefficient energy redistribution. Finally, we attribute the photometric variability to the stellar rotation, either through superficial inhomogeneities or resonance couplings between the convective core and the radiative envelope. Conclusions: Based on the derived system architecture, we predict the eclipse depth in the upcoming Transiting Exoplanet Survey Satellite (TESS) observations to be up to ~165 ppm. High-precision detection of the eclipse in both CHEOPS and TESS passbands might help disentangle reflective and thermal contributions. We also expect the right ascension of the ascending node of the orbit to precess due to the perturbations induced by the stellar quadrupole moment J2 (oblateness). Raw and detrended light curves are only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/cat/J/A+A/659/A7

CHEOPS launch in 2019! – Payload Capabilities and In-Orbit Commissioning Preview

ESA Science Programme Committee (SPC) selected CHEOPS as the first small class science mission in 2012. CHEOPS is considered as a pilot case for the implementation of “small science missions” and its success is key for the continuation of fast-paced, small missions. The mission has been developed and brought into a flight readiness state within 5-6 years from selection, which is about half the time of other ESA missions. This paper focuses on the CHEOPS payload and its predicted capabilities. The 300mm effective aperture Ritchey-Chretien telescope provided by the CHEOPS consortium has been tested and characterized on ground in a 2 months calibration campaign after the qualification for flight. The results have led to performance estimations, which are discussed here. We show that the performance requirements in flight are expected to be met by the instrument. A preview is given towards the 2 months lasting In Orbit Commissioning (IOC) phase of the CHEOPS payload after LEOP and platform check-out. The activities in orbit range from dark current measurements, PSF characterization and parasitic stray light determination to AOCS and instrument performance verifications to science validation using reference transits