28 research outputs found

    First events from the CNGS neutrino beam detected in the OPERA experiment

    Get PDF
    The OPERA neutrino detector at the underground Gran Sasso Laboratory (LNGS) was designed to perform the first detection of neutrino oscillations in appearance mode, through the study of nu_mu to nu_tau oscillations. The apparatus consists of a lead/emulsion-film target complemented by electronic detectors. It is placed in the high-energy, long-baseline CERN to LNGS beam (CNGS) 730 km away from the neutrino source. In August 2006 a first run with CNGS neutrinos was successfully conducted. A first sample of neutrino events was collected, statistically consistent with the integrated beam intensity. After a brief description of the beam and of the various sub-detectors, we report on the achievement of this milestone, presenting the first data and some analysis results.Comment: Submitted to the New Journal of Physic

    Spontaneous Regression of an Inflammatory Myofibroblastic Tumor: A Case Report and a Review of the Literature

    Get PDF
    Introduction: Spontaneous tumor regression is the volumetric reduction or complete disappearance of a primary tumor or metastatic sites (single or multiple) without the administration of treatments. This rare phenomenon occurs most commonly in certain types of neoplasms. Case Presentation: In this manuscript, we describe a spontaneous tumor regression in an adult patient followed at the Modena Cancer Center and affected by retroperitoneal inflammatory myofibroblastic tumor, an ultra-rare subtype of sarcoma. Finally, we will provide a concise review of the literature and try to explain the mechanisms underlying the tumor regression described in the clinical case. Conclusion: The etiopathogenetic mechanisms for spontaneous tumor regression are not yet fully understood and likely involve a complex interplay among immunological mechanisms, growth factors, cytokines, and hormonal factors

    Early Onset Metastatic Colorectal Cancer: Current Insights and Clinical Management of a Rising Condition

    Get PDF
    Despite a recent overall decrease in colorectal cancer (CRC) incidence and mortality, there has been a significant rise in CRC diagnoses in young adults. Early onset colorectal cancer (EOCRC) is defined as CRC diagnosed before the age of 50. Possible predisposing conditions include not only genetic syndromes but also other risk factors, such as microbiome alteration, antibiotic exposure, obesity, diabetes mellitus, and inflammatory bowel disease. EOCRC tends to be diagnosed later than in the older counterpart because of a lack of awareness and the fact that screening for CRC usually starts at the age of 50. Furthermore, CRC in young adults seems to be related to unique molecular features and more aggressive clinical behavior. This paper aims to provide an in-depth review of this poorly understood subject, with a comprehensive review of the state of the art and considerations for future perspectives

    La valutazione dell' uso e della sicurezza dei farmaci: esperienze in Italia. Riassunti

    No full text
    Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

    Studio pilota per la definizione di metodologie di valutazione e controllo delle prescrizione e del consumo dei farmaci

    No full text
    Consiglio Nazionale delle Ricerche, Biblioteca Centrale, P.le Aldo Moro, 7, ROMA (Italia) / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

    L'uso degli strumenti neuropsicologici nell'ambito del Progetto Cronos.

    No full text
    Nell’ambito del Progetto Cronos sono state attivate sull’intero territorio nazionale 503 Unità di Valutazione Alzheimer (UVA). Nel periodo di giugno/luglio 2002 è stata inviata a tutti i centri UVAuna scheda di rilevazione tramite la quale veniva raccolta l’informazione sugli strumenti neuropsicologici comunemente utilizzati nel processo diagnostico delle demenze. Solo 196 delle UVA che hanno risposto al questionario (196/392) dichiarano di utilizzare test e batterie neuropsicologiche, mentre il 97,8% dichiara di utilizzare il mini mental state examination (MMSE). Questo contributo ha l’obiettivo di censire, per la prima volta in Italia, l’uso degli strumenti neuropsicologici comunemente utilizzati nelle strutture assistenziali deputate alla diagnosi e al trattamento delle demenze e di proporre un approfondimento metodologico strettamente legato alla validazione dei test. P a role chiave: test neuropsicologici, Progetto Cronos, demenza di A l z h e i m e
    corecore