120 research outputs found
Unlocking the potential of ancient fish DNA in the genomic era.
Fish are the most diverse group of vertebrates, fulfil important ecological functions and are of significant economic interest for aquaculture and wild fisheries. Advances in DNA extraction methods, sequencing technologies and bioinformatic applications have advanced genomic research for nonmodel organisms, allowing the field of fish ancient DNA (aDNA) to move into the genomics era. This move is enabling researchers to investigate a multitude of new questions in evolutionary ecology that could not, until now, be addressed. In many cases, these new fields of research have relevance to evolutionary applications, such as the sustainable management of fisheries resources and the conservation of aquatic animals. Here, we focus on the application of fish aDNA to (a) highlight new research questions, (b) outline methodological advances and current challenges, (c) discuss how our understanding of fish ecology and evolution can benefit from aDNA applications and (d) provide a future perspective on how the field will help answer key questions in conservation and management. We conclude that the power of fish aDNA will be unlocked through the application of continually improving genomic resources and methods to well-chosen taxonomic groups represented by well-dated archaeological samples that can provide temporally and/or spatially extensive data sets
Negative outcomes evoke cyclic irrational decisions in Rock, Paper, Scissors
Rock, Paper, Scissors (RPS) represents a unique gaming space in which the predictions of human
rational decision-making can be compared with actual performance. Playing a computerized opponent
adopting a mixed-strategy equilibrium, participants revealed a non-significant tendency to over-select
Rock. Further violations of rational decision-making were observed using an inter-trial analysis where
participants were more likely to switch their item selection at trial n + 1 following a loss or draw at
trial n, revealing the strategic vulnerability of individuals following the experience of negative rather
than positive outcome. Unique switch strategies related to each of these trial n outcomes were also
identified: after losing participants were more likely to ‘downgrade’ their item (e.g., Rock followed by
Scissors) but after drawing participants were more likely to ‘upgrade’ their item (e.g., Rock followed by
Paper). Further repetition analysis revealed that participants were more likely to continue their specific
cyclic item change strategy into trial n + 2. The data reveal the strategic vulnerability of individuals
following the experience of negative rather than positive outcome, the tensions between behavioural
and cognitive influences on decision making, and underline the dangers of increased behavioural
predictability in other recursive, non-cooperative environments such as economics and politics
Left gaze bias in humans, rhesus monkeys and domestic dogs
While viewing faces, human adults often demonstrate a natural gaze bias towards the left visual field, that is, the right side of the viewee’s face is often inspected first and for longer periods. Using a preferential looking paradigm, we demonstrate that this bias is neither uniquely human nor limited to primates, and provide evidence to help elucidate its biological function within a broader social cognitive framework. We observed that 6-month-old infants showed a wider tendency for left gaze preference towards objects and faces of different species and orientation, while in adults the bias appears only towards upright human faces. Rhesus monkeys showed a left gaze bias towards upright human and monkey faces, but not towards inverted faces. Domestic dogs, however, only demonstrated a left gaze bias towards human faces, but not towards monkey or dog faces, nor to inanimate object images. Our findings suggest that face- and species-sensitive gaze asymmetry is more widespread in the animal kingdom than previously recognised, is not constrained by attentional or scanning bias, and could be shaped by experience to develop adaptive behavioural significance
Synthetic biology: Understanding biological design from synthetic circuits
An important aim of synthetic biology is to uncover the design principles of natural biological systems through the rational design of gene and protein circuits. Here, we highlight how the process of engineering biological systems — from synthetic promoters to the control of cell–cell interactions — has contributed to our understanding of how endogenous systems are put together and function. Synthetic biological devices allow us to grasp intuitively the ranges of behaviour generated by simple biological circuits, such as linear cascades and interlocking feedback loops, as well as to exert control over natural processes, such as gene expression and population dynamics
Wire-Tightener
Patent for invented certain new and useful improvement in Wire-Tightener invention relates to an improvement in and it consists in the peculiar construction and combination of devices, that will be more fully set here in after and particularly pointed out in the claim
Density Functional Theory Guide for an Allyl Monomer Polymerization Mechanism: Photoinduced Radical-Mediated [3 + 2] Cyclization
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