Utilization of heat precipitated whey protein

The purpose of this study was to coagulate whey protein by heat denaturation, recover it, and use it in food products. Fresh liquid whey at pH 4.5 was heated at 90°C for 20 minutes. Heated whey was cooled to room temperature (about 25°C) and centrifuged 15 minutes at 750xg. About 42 percent of the protein was recovered. The mean particle diameter of the sedimented material was 29.5μ. Electrophoresis indicated that blood serum albumin and 3-lactoglobulin were essentially precipitated while some a-lactalbumin remained in suspension. The sediment was collected and used as a basic matrix in sandwich spread and as a partial replacement of NFDM in ice cream. The products showed desirable quality when examined by sensory panels. Up to 30 per-cent of the NFDM in ice cream could be replaced

The effects of acylation on the functionality and performance of cottonseed flour

The purposes of this study were to acylate glandless cottonseed flour by using succinic anhydride and then to study the functionality and performance of acylated flour. Glandless cottonseed flour was acylated by adding one-tenth gram of succinic anhydride per gram flour. The anhydride was added to the flour suspension over a period of 60 minutes with constant stirring at room temperature (23-24°C.). The pH of the reaction was maintained at pH 8 (±0.5) by addition of 50 percent NaOH. After the reaction was finished, the pH of the flour suspension was lowered to pH 4 (±0.5). The acylated flour was recovered by centrifugation, washed with water to remove residual succinate, and freeze-dried. Physical functionality of acylated cottonseed flour was measured, Water and oil holding capacities were increased while emulsifying capacity was reduced. Acylated cottonseed flour and untreated cottonseed flour were used as a replacement for 6 or 12 percent of the wheat flour in white layer cakes. The quality of these cakes was inferior to controls made with all wheat flour

WEB ATTACKS AND DEFENSES

Because of the limited data that web applications collect from users, they are subject to information security risks. The most effective way to retain data in the modern era is through online applications. The process of providing data and data systems with appropriate procedural and sophisticated security safeguards is known as cybersecurity. Threats to cyber security are increasing at times. A flaw or weakness in a computer system, security tactics, internal controls, planning, or implementation that can compromise the security policy of a framework is known as a web vulnerability. The social, economic and political spheres of governments can be disrupted due to a vulnerability in the Internet, which can have an impact on the state. An effort is made to identify the defects and weaknesses while studying the weakness in order to take advantage of these weaknesses. The aim of this study is to identify the types of intrusions, find vulnerabilities, and review regulations for vulnerable systems detected in online applications

Investigation into the characteristics of proton exchange membrane fuel cell-based power system

© The Institution of Engineering and Technology.Fuel cells (FCs) use hydrogen as their prime fuel source, which promotes them as one of the attractive options for clean energy generators. Though they have been around for some time, their characteristics are not yet fully understood. This study offers a thorough investigation into the characteristics of proton exchange membrane (PEM) type of FCs based power system. This study first presents a concise explanation of the working principles of the PEM electrolyser and FCs supported by novel modelling using MATLAB. The simulation results are then validated by a series of experiments carried out on operational 500 mW FC followed by detailed performance parameters of such type of FCs. Parameters affect the efficiencies of each part of the system are investigated and the total system's efficiency is then calculated. The efficiency of the electrolyser and PEM FC was found to be 85 and 60%, respectively. Polarisation curve has been used in order to evaluate FC's performance. From the polarisation curve, it is noted the efficiency of the FC increases with increasing pressure and temperature. The activation losses are reduced when the temperature increased. Moreover, the mass transfer is enhanced toward reducing the PEMFC's resistance

Risk factors for pre-term birth in Iraq: a case-control study

BACKGROUND: Preterm birth (PTB)is a major clinical problem associated with perinatal mortality and morbidity. The aim of the present study is to identify risk factors associated with PTB in Mosul, Iraq. METHODS: A case-control study was conducted in Mosul, Iraq, from 1(st )September, 2003 to 28(th )February, 2004. RESULTS: A total of 200 cases of PTB and 200 controls of full-term births were screened and enrolled in the study. Forward logistic regression analysis was used in the analysis. Several significant risk associations between PTB and the following risk factors were identified: poor diet (OR = 4.33), heavy manual work (OR = 1.70), caring for domestic animals (OR = 5.06), urinary tract infection (OR = 2.85), anxiety (OR = 2.16), cervical incompetence (OR = 4.74), multiple pregnancies (OR = 7.51), direct trauma to abdomen (OR = 3.76) and abortion (OR = 6.36). CONCLUSION: The main determinants of PTB in Iraq were low socio-economic status and factors associated with it, such as heavy manual work and caring for domestic animals, in addition to urinary tract infections and poor obstetric history

Regenerative endodontics: a true paradigm shift or a bandwagon about to be derailed?

Aims: Regenerative endodontic techniques (RETs) have been hailed as a paradigm shift for the management of traumatised non-vital immature permanent anterior teeth. In this article the aim was to critically appraise the literature with regards to the outcome of regenerative endodontics on root development. Methods: Critical review of the literature where regenerative endodontic techniques have been used in the management of immature non-vital teeth with continuation of root development as the main outcome reported. Results: Most studies published were in the form of case reports and series with very few randomised controlled trials with a high risk of bias. Continuation of root development following the use of RET has been shown to be unpredictable at best with lower success in those teeth losing vitality as a result of dental trauma. Conclusions: Despite the high success of regenerative endodontics in terms of periodontal healing including resolution of clinical and radiographic signs and symptoms of infection, continuation of root development remains an unpredictable outcome. The use of a blood clot as a scaffold in regenerative endodontics should be reviewed carefully as that might offer an environment for repair rather than regeneration. In addition, preservation of structures, such as Hertwig’s epithelial root sheath, may have an important bearing on the success of this approach and should be further investigated

Review of nanomaterials in dentistry: interactions with the oral microenvironment, clinical applications, hazards, and benefits.

Interest in the use of engineered nanomaterials (ENMs) as either nanomedicines or dental materials/devices in clinical dentistry is growing. This review aims to detail the ultrafine structure, chemical composition, and reactivity of dental tissues in the context of interactions with ENMs, including the saliva, pellicle layer, and oral biofilm; then describes the applications of ENMs in dentistry in context with beneficial clinical outcomes versus potential risks. The flow rate and quality of saliva are likely to influence the behavior of ENMs in the oral cavity, but how the protein corona formed on the ENMs will alter bioavailability, or interact with the structure and proteins of the pellicle layer, as well as microbes in the biofilm, remains unclear. The tooth enamel is a dense crystalline structure that is likely to act as a barrier to ENM penetration, but underlying dentinal tubules are not. Consequently, ENMs may be used to strengthen dentine or regenerate pulp tissue. ENMs have dental applications as antibacterials for infection control, as nanofillers to improve the mechanical and bioactive properties of restoration materials, and as novel coatings on dental implants. Dentifrices and some related personal care products are already available for oral health applications. Overall, the clinical benefits generally outweigh the hazards of using ENMs in the oral cavity, and the latter should not prevent the responsible innovation of nanotechnology in dentistry. However, the clinical safety regulations for dental materials have not been specifically updated for ENMs, and some guidance on occupational health for practitioners is also needed. Knowledge gaps for future research include the formation of protein corona in the oral cavity, ENM diffusion through clinically relevant biofilms, and mechanistic investigations on how ENMs strengthen the tooth structure

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021. Methods We estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined. Findings Globally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer. Interpretation As the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed. Funding Bill & Melinda Gates Foundation