27 research outputs found
Mobile brain/body imaging of landmark-based navigation with high-density EEG.
Coupling behavioral measures and brain imaging in naturalistic, ecological conditions is key to comprehend the neural bases of spatial navigation. This highly integrative function encompasses sensorimotor, cognitive, and executive processes that jointly mediate active exploration and spatial learning. However, most neuroimaging approaches in humans are based on static, motion-constrained paradigms and they do not account for all these processes, in particular multisensory integration. Following the Mobile Brain/Body Imaging approach, we aimed to explore the cortical correlates of landmark-based navigation in actively behaving young adults, solving a Y-maze task in immersive virtual reality. EEG analysis identified a set of brain areas matching state-of-the-art brain imaging literature of landmark-based navigation. Spatial behavior in mobile conditions additionally involved sensorimotor areas related to motor execution and proprioception usually overlooked in static fMRI paradigms. Expectedly, we located a cortical source in or near the posterior cingulate, in line with the engagement of the retrosplenial complex in spatial reorientation. Consistent with its role in visuo-spatial processing and coding, we observed an alpha-power desynchronization while participants gathered visual information. We also hypothesized behavior-dependent modulations of the cortical signal during navigation. Despite finding few differences between the encoding and retrieval phases of the task, we identified transient time-frequency patterns attributed, for instance, to attentional demand, as reflected in the alpha/gamma range, or memory workload in the delta/theta range. We confirmed that combining mobile high-density EEG and biometric measures can help unravel the brain structures and the neural modulations subtending ecological landmark-based navigation
High-frequency ultrasonic speckle velocimetry in sheared complex fluids
High-frequency ultrasonic pulses at 36 MHz are used to measure velocity
profiles in a complex fluid sheared in the Couette geometry. Our technique is
based on time-domain cross-correlation of ultrasonic speckle signals
backscattered by the moving medium. Post-processing of acoustic data allows us
to record a velocity profile in 0.02--2 s with a spatial resolution of 40
m over 1 mm. After a careful calibration using a Newtonian suspension, the
technique is applied to a sheared lyotropic lamellar phase seeded with
polystyrene spheres of diameter 3--10 m. Time-averaged velocity profiles
reveal the existence of inhomogeneous flows, with both wall slip and shear
bands, in the vicinity of a shear-induced ``layering'' transition. Slow
transient regimes and/or temporal fluctuations can also be resolved and exhibit
complex spatio-temporal flow behaviors with sometimes more than two shear
bands.Comment: 15 pages, 18 figures, submitted to Eur. Phys. J. A
Quantitative imaging of concentrated suspensions under flow
We review recent advances in imaging the flow of concentrated suspensions,
focussing on the use of confocal microscopy to obtain time-resolved information
on the single-particle level in these systems. After motivating the need for
quantitative (confocal) imaging in suspension rheology, we briefly describe the
particles, sample environments, microscopy tools and analysis algorithms needed
to perform this kind of experiments. The second part of the review focusses on
microscopic aspects of the flow of concentrated model hard-sphere-like
suspensions, and the relation to non-linear rheological phenomena such as
yielding, shear localization, wall slip and shear-induced ordering. Both
Brownian and non-Brownian systems will be described. We show how quantitative
imaging can improve our understanding of the connection between microscopic
dynamics and bulk flow.Comment: Review on imaging hard-sphere suspensions, incl summary of
methodology. Submitted for special volume 'High Solid Dispersions' ed. M.
Cloitre, Vol. xx of 'Advances and Polymer Science' (Springer, Berlin, 2009);
22 pages, 16 fig
Soft Dynamics simulation: 2. Elastic spheres undergoing a T1 process in a viscous fluid
Robust empirical constitutive laws for granular materials in air or in a
viscous fluid have been expressed in terms of timescales based on the dynamics
of a single particle. However, some behaviours such as viscosity bifurcation or
shear localization, observed also in foams, emulsions, and block copolymer
cubic phases, seem to involve other micro-timescales which may be related to
the dynamics of local particle reorganizations. In the present work, we
consider a T1 process as an example of a rearrangement. Using the Soft dynamics
simulation method introduced in the first paper of this series, we describe
theoretically and numerically the motion of four elastic spheres in a viscous
fluid. Hydrodynamic interactions are described at the level of lubrication
(Poiseuille squeezing and Couette shear flow) and the elastic deflection of the
particle surface is modeled as Hertzian. The duration of the simulated T1
process can vary substantially as a consequence of minute changes in the
initial separations, consistently with predictions. For the first time, a
collective behaviour is thus found to depend on another parameter than the
typical volume fraction in particles.Comment: 11 pages - 5 figure
Active surveillance of bat rabies in France: A 5-year study (2004–2009)
Active surveillance of bats in France started in 2004 with an analysis of 18 of the 45 bat species reported in Europe. Rabies antibodies were detected in six indigenous species, mainly in Eptesicus serotinus and Myotis myotis, suggesting previous contact with the EBLV-1 rabies virus. Nineteen of the 177 tested bats were shown serologically positive in seven sites, particularly in central and south-western France. Neither infectious viral particles nor viral genomes were detected in 173 and 308 tested oral swabs, respectively. The presence of neutralising antibodies in female bats (18.6%) was significantly higher than in males (5.6%)
Phenomenology and physical origin of shear-localization and shear-banding in complex fluids
We review and compare the phenomenological aspects and physical origin of
shear-localization and shear-banding in various material types, namely
emulsions, suspensions, colloids, granular materials and micellar systems. It
appears that shear-banding, which must be distinguished from the simple effect
of coexisting static-flowing regions in yield stress fluids, occurs in the form
of a progressive evolution of the local viscosity towards two significantly
different values in two adjoining regions of the fluids in which the stress
takes slightly different values. This suggests that from a global point of view
shear-banding in these systems has a common physical origin: two physical
phenomena (for example, in colloids, destructuration due to flow and
restructuration due to aging) are in competition and, depending on the flow
conditions, one of them becomes dominant and makes the system evolve in a
specific direction.Comment: The original publication is available at http://www.springerlink.co
Recent experimental probes of shear banding
Recent experimental techniques used to investigate shear banding are
reviewed. After recalling the rheological signature of shear-banded flows, we
summarize the various tools for measuring locally the microstructure and the
velocity field under shear. Local velocity measurements using dynamic light
scattering and ultrasound are emphasized. A few results are extracted from
current works to illustrate open questions and directions for future research.Comment: Review paper, 23 pages, 11 figures, 204 reference