401 research outputs found

    The Creative Class and the Creative Economy in Spain

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    This article describes an application in Spain of Florida's model (2002/Citation2010, Citation2005) about creativity, economy and growth. Creativity is an indicator that measures and combines technology, talent, and tolerance. Each of these is composed of three subindices. The most important conclusion from the data reported here is that creativity in particular, and growth in general, was less related to tolerance than the other two indices. However, the subindex of tolerance reflecting bohemia was important; the other two (foreigners and gays) were not

    Extracellular cysteine in connexins: Role as redox sensors

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    Indexación: Scopus.Connexin-based channels comprise hemichannels and gap junction channels. The opening of hemichannels allow for the flux of ions and molecules from the extracellular space into the cell and vice versa. Similarly, the opening of gap junction channels permits the diffusional exchange of ions and molecules between the cytoplasm and contacting cells. The controlled opening of hemichannels has been associated with several physiological cellular processes; thereby unregulated hemichannel activity may induce loss of cellular homeostasis and cell death. Hemichannel activity can be regulated through several mechanisms, such as phosphorylation, divalent cations and changes in membrane potential. Additionally, it was recently postulated that redox molecules could modify hemichannels properties in vitro. However, the molecular mechanism by which redox molecules interact with hemichannels is poorly understood. In this work, we discuss the current knowledge on connexin redox regulation and we propose the hypothesis that extracellular cysteines could be important for sensing changes in redox potential. Future studies on this topic will offer new insight into hemichannel function, thereby expanding the understanding of the contribution of hemichannels to disease progression.http://journal.frontiersin.org/article/10.3389/fphys.2016.00001/ful

    Microtensile bond strength of adhesive layer contaminated with blood on human sound enamel

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    Indexación: Web of Science; Scielo.Objetivo: Evaluar la influencia de la contaminación con sangre en una capa de adhesivo formada sobre esmalte humano y su posterior descontaminación con NaOCl (2.5%) y etanol (70°) en la resistencia microtraccional. Métodos: La superficie vestibular de 80 premolares humanos fue fresada para obtener superficies planas sobre las que se aplicó un adhesivo de grabado y lavado siguiendo las indicaciones del fabricante (Adper Single Bond 2, 3M ESPE). Los premolares fueron distribuidos aleatoriamente en cuatro grupos: Grupo 1 (control), Grupo 2 (contaminación con sangre), Grupo 3 (descontaminación con NaOCl 2.5%) y Grupo 4 (descontaminación con etanol 70°). Luego, sobre cada premolar se confeccionó una corona de resina compuesta (Filtek Z350, 3M ESPE) y fueron cortados para obtener cuerpos de prueba de 1mm2 de sección transversal, los cuales fueron termociclados (5500 ciclos, 5-55°C) y traccionados hasta su límite de ruptura (Micro Tensile Tester, Bisco). Los resultados fueron analizados estadísticamente (ANOVA, Scheffe, p0.05). Conclusión: La contaminación con sangre de la capa de adhesivo interfiere significativamente en la resistencia microtraccional. La descontaminación con NaOCl o etanol no logró una recuperación de la resistencia microtraccional.Aim: To evaluate the influence of blood contamination of the adhesive layer and posterior decontamination with NaOCl (2.5%) and ethanol (70º) on microtensile bond strength on human enamel. Methods: Vestibular surfaces of eighty human premolars were grounded to obtain flat surfaces. An etch-and-rinse adhesive was applied according to the manufacturer’s instructions (Adper Single bond 2, 3M ESPE). Teeth were randomly assigned into 4 groups: Group 1 (control), Group 2 (blood contamination), Group 3 (decontamination with NaOCl 2.5%) and Group 4 (decontamination with ethanol 70º). Then, a 4mm composite crown (Filtek Z350) was made and the teeth were vertically sectioned to obtain 1mm cross-section stick shape specimens. Specimens were thermocycled (5500 cycles, 5-55ºC) and pulled under tension until failure (Micro Tensile Tester, Bisco). Results were statistically analyzed (ANOVA, Scheffe’s test, p0.05). Conclusion: Blood contamination significantly interferes in microtensile bond strength. Decontaminating the blood residues with NaOCl or ethanol did not show a recovery of bond strength.http://ref.scielo.org/3zrh4

    Experimental determination of the absorption strength in absorbing chaotic cavities

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    Due to the experimental necessity we present a formula to determine the absorption strength by power losses inside a chaotic system (cavities, graphs, acoustic resonators, etc) when the antenna coupling, always present in experimental measurements, is taken into account. This is done by calculating the average of the absorption coefficient as a function of the absorption strength and the coupling of the antenna to the system, in the one channel case.Comment: 6 pages, 3 figures, Submitted to Phys. Rev.

    Self-adhesive flowable composite-resin as a fissure sealant. A microleakage study

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    Indexación: Web of Science; ScieloRESUMEN Objetivo: Evaluar la capacidad de sellado de una resina fluida autoadhesiva (Fusio Liquid Dentin, Pentron Clinical) utilizada como sellante de fosas y fisuras con distintos acondicionamientos de la superficie de esmalte. Materiales y Métodos: Se seleccionaron 140 terceros molares recientemente extraídos, los que fueron distribuidos aleatoriamente en cuatro grupos (n=35) y recibieron una técnica de acondicionamiento del esmalte y aplicación de un sellante. Se establecieron los siguientes grupos: Grupo 1, grabado ácido y aplicación de sellante (Clinpro, 3M ESPE); Grupo 2, grabado ácido y aplicación de resina autoadhesiva (Fusio Liquid Dentin, Pentron Clinical); Grupo 3, aplicación de resina autoadhesiva; Grupo 4, microarenado del esmalte y aplicación de resina autoadhesiva. Los dientes sellados fueron termociclados (500 ciclos, 5-55°C), y posteriormente sumergidos en solución de nitrato de plata amoniacal por 24 h (pH=14) y luego en revelador radiográfico (GBX, Kodak) por 8h. Posteriormente, los dientes fueron cortados para obtener 2 láminas por diente que fueron observadas bajo magnificación (4x) y analizadas digitalmente para evaluar la microinfiltración y la penetración en la fisura. Los resultados fueron analizados estadísticamente (ANOVA, Dunnett, p<0.05). Resultados: La microinfiltración del Grupo 1 (13.18 ± 9.25%) fue significativamente menor que la de los grupos 2, 3 y 4 (p<0.05). La penetración en la fisura en el Grupo 1 (98.92 ± 2.77%) fue mayor que en los otros grupos, siendo esta diferencia significativa sólo con el Grupo 4. Conclusión: Fusio Liquid Dentin tiene una capacidad de sellado inferior a la del sellante convencional Clinpro, independiente del acondicionamiento del esmalte que se utilice.ABSTRACT Aim: To evaluate the sealing ability of a self-adhesive flowable composite-resin (Fusio Liquid Dentin, Pentron Clinical) with different conditioning treatments of the enamel surface used as a fissure sealant. Materials and Method: 140 recently extracted human third molars were selected and randomly divided into four groups (n=35). Each group received an enamel conditioning treatment and a sealant application. The following groups were established: Group 1, acid etching and sealant application (Clinpro, 3M ESPE); Group 2, acid etching and self-adhesive flowable composite-resin (Fusio Liquid Dentin, Pentron Clinical); Group 3, self-adhesive flowable composite-resin; Group 4, sandblasting and self-adhesive flowable composite-resin. Sealed teeth were thermocycled (500 cycles, 5-55ºC) and immersed in ammoniacal silver nitrate solution for 24 h (ph=14). After that, the teeth were immersed in radiographic developer solution (GBX, Kodak) for 8 h. Then, the teeth were vertically sectioned to obtain two slides each that were observed under magnification (4x) and digitally analyzed to assess microleakage and sealant penetration. Results were statistically analyzed (ANOVA, Dunnett, p<0.05). Results: Microleakage of Group 1 (13.18 ± 9.25%) was significantly lower than groups 2, 3 and 4 (p<0.05). Group 1 had the highest sealant penetration mean (98.92 ± 2.77%). Conclusion: Fusio Liquid Dentin had a worse sealing ability than Clinpro irrespective of their enamel conditioning treatment when used as a fissure sealant. Among Fusio’s groups, acid etching was the best enamel surface conditioning treatment.http://www.scielo.cl/pdf/piro/v6n1/art01.pd

    CLIWOC multilingual meteorological dictionary

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    This dictionary is the first attempt to express the wealth of archaic logbook wind force terms in a form that is comprehensible to the modern-day reader. Oliver and Kington (1970) and Lamb (1982) have drawn attention to the importance of logbooks in climatic studies, and Lamb (1991) offered a conversion scale for early eighteenth century English wind force terms, but no studies have thus far pursued the matter to any greater depth. This text attempts to make good this deficiency, and is derived from the research undertaken by the CLIWOC project1 in which British, Dutch, French and Spanish naval and merchant logbooks from the period 1750 to 1850 were used to derive a global database of climatic information. At an early stage in the project it was apparent that many of the logbook weather terms, whilst conforming to a conventional vocabulary, possessed meanings that were unclear to twenty-first century readers or had changed over time. This was particularly the case for the important element of wind force; but no special plea is entered for the evolution in nautical vocabulary, which often reflected more wide-ranging changes in the respective native languages.The key objective was to translate the archaic vocabulary of the late eighteenth and early nineteenth century mariner into expressions directly comparable with the Beaufort Scale (see Appendix I). Only then could the projects scientific programme be embarked upon. This dictionary is the result of the largest undertaking into logbook studies that has yet been carried out. Several thousand logbooks from British, Dutch, French and Spanish archives were examined, and the exercise offered a unique opportunity to explore the vocabulary of the one hundred year period beginning in 1750. The logbooks from which the raw data have been abstracted range widely across the North and South Atlantic and the Indian Oceans. Only the Pacific, largely in consequence of the paucity of regular naval activity in that area, is not well represented. The range of climates encountered in this otherwise wide geographic domain gives ample opportunity for the full range of the mariners nautical weather vocabulary to be assessed, from the calms of the Equatorial regions, through the gales of the mid-latitude systems to the fearsome storms of the tropical latitudes. The Trade Winds belts, the Doldrums, the unsettled mid-latitudes, even the icy wastes of the high latitudes, are all embraced in this study. It is not here intended to pass any judgements on the climatological record of the logbooks, and this text seeks only to provide a means of understanding archaic wind force terms and, other than to indicate those items that were not commonly used, no information is given on the frequency with which different terms appeared in the logbooks. Attention is, furthermore, confined to Dutch, English, French and Spanish because these once great imperial powers were the only nations able to support wide-ranging ocean-going fleets with their attendant collections of logbooks and documents over this long period of time. The work is offered to the wider academic community in the hope that they will prove to be of as much value as it has been to the CLIWOC team

    Two-dimensional tunneling in a SQUID

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    Traditionally quantum tunneling in a static SQUID is studied on the basis of a classical trajectory in imaginary time under a two-dimensional potential barrier. The trajectory connects a potential well and an outer region crossing their borders in perpendicular directions. In contrast to that main-path mechanism, a wide set of trajectories with components tangent to the border of the well can constitute an alternative mechanism of multi-path tunneling. The phenomenon is essentially non-one-dimensional. Continuously distributed paths under the barrier result in enhancement of tunneling probability. A type of tunneling mechanism (main-path or multi-path) depends on character of a state in the potential well prior to tunneling.Comment: 9 pages, 8 figure

    The Triple Higgs Boson Self-Coupling at Future Linear e+e- Colliders Energies: ILC and CLIC

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    We analyzed the triple Higgs boson self-coupling at future e+ee^{+}e^{-} colliders energies, with the reactions e+ebbˉHH,ttˉHHe^{+}e^{-}\to b \bar b HH, t \bar t HH. We evaluate the total cross-sections for both bbˉHHb\bar bHH and ttˉHHt\bar tHH, and calculate the total number of events considering the complete set of Feynman diagrams at tree-level. We vary the triple coupling κλ3H\kappa\lambda_{3H} within the range κ=1\kappa=-1 and +2. The numerical computation is done for the energies expected to be available at a possible Future Linear e+ee^{+}e^{-} Collider with a center-of-mass energy 800,1000,1500800, 1000, 1500 GeVGeV and a luminosity 1000 fb1fb^{-1}. Our analysis is also extended to a center-of-mass energy 3 TeVTeV and luminosities of 1000 fb1fb^{-1} and 5000 fb1fb^{-1}. We found that for the process e+ebbˉHHe^{+}e^{-}\to b \bar b HH, the complete calculation differs only by 3% from the approximate calculation e+eZHH(Zbbˉ)e^{+}e^{-}\to ZHH(Z\to b\bar b), while for the process e+ettˉHHe^{+}e^{-}\to t \bar tHH, the expected number of events, considering the decay products of both tt and HH, is not enough to obtain an accurate determination of the triple Higgs boson self-coupling.Comment: 19 pages, 12 figure

    Casuística de leishmaniosis visceral canina registrada en Corrientes (Argentina) durante el período 2014-2016

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    Since the years 2014 to 2016, cases of visceral leishmaniosis were investigated in canines examined at the Faculty of Veterinary Sciences of Corrientes, Argentina. The study was carried out through the indirect method (detection of antibodies against the rk39 antigen in venous blood serum) and the direct test (extraction of bone marrow by ribs puncture and microscopic observation of amastigotes). During these three years, 409 patients were examined. In 2014 there were 22/89 positive cases (24.7%), in 2015 there were 39/164 positive cases (23.7%) and in 2016 there were 56/156 positive patients (35.8%). In all cases, the canines were positive for both methods. The average prevalence of leishmaniosis in canines studied during this period was 28.6%. It is emphasized that in presence of patients suspected of suffering visceral canine leishmaniosis, serological (indirect) and parasitological (direct) diagnostic methods should be performed together. Durante los meses de febrero a octubre de los años 2014 a 2016 se investigó el padecimiento de leishmaniosis visceral en caninos atendidos en la Facultad de Ciencias Veterinarias de Corrientes, Argentina. El estudio se efectuó a través del método indirecto (detección de anticuerpos contra el antígeno rK39 en suero de sangre venosa) y la prueba directa (extracción de medula ósea por punción en distal de costillas y observación microscópica de amastigotes). Durante los 3 años se examinaron un total de 409 pacientes. En 2014 (89 muestras) se registraron 22 casos positivos (24,7%); en 2015 (164 muestras) se detectaron 39 casos positivos (23,7%) y en 2016 (156 muestras) se revelaron 56 pacientes positivos (35,8%). En todos los casos los caninos fueron positivos a ambos métodos diagnósticos. En el total de años estudiados, la prevalencia en caninos fue de 28,06%. Se enfatiza que ante los pacientes sospechosos de padecer leishmaniosis visceral, se efectúen conjuntamente los métodos diagnósticos serológico (indirecto) y parasitológico (directo)
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