126 research outputs found
Le mentorat en dĂ©but de carriĂšre : retombĂ©es sur la charge professorale et conditions de mise en Ćuvre dâun programme en milieu universitaire
Cette synthĂšse dâĂ©crits a Ă©tĂ© menĂ©e dans le but de faire Ă©tat des retombĂ©es du mentorat en milieu Ă©ducatif, plus prĂ©cisĂ©ment, le mentorat destinĂ© aux enseignants universitaires en dĂ©but de carriĂšre et des conditions de mise en Ćuvre dâun programme. Les principaux constats tirĂ©s de cette synthĂšse montrent que la question du mentorat informel par rapport au mentorat formel reste sans rĂ©ponse dĂ©finitive quant Ă la supĂ©rioritĂ© dâune forme sur lâautre. De plus, en dĂ©pit des divergences de points de vue dans la littĂ©rature, il ressort que le mentorat joue un rĂŽle positif dans le dĂ©veloppement professionnel des nouveaux enseignants pour lâensemble des fonctions composant leur charge professorale, incluant la fonction enseignement. Enfin, les expĂ©riences menĂ©es dans diffĂ©rents Ă©tablissements nous permettent dâexaminer des modalitĂ©s dâimplantation et de fonctionnement ainsi que de proposer un modĂšle de mentorat en trois Ă©tapes.This review of the literature was carried out in order to assess the impact of mentoring in educational settings and in particular mentoring addressing faculty in early stages of their academic career and the necessary requirements for implementing programmes. The main issues raised by our study indicate that as far as informal mentoring and formal mentoring are concerned there is no definite answer regarding the efficiency of one over the other. Furthermore despite contrasted views in the literature, it seems that mentoring does have a positive impact on professional development of early stage academics for most of the components of their professorial function including teaching. Last of all experiences carried out in various institutions allowed us to examine implementation and practise in mentoring and to devise a framework comprising three steps
Quasi-analyticity and determinacy of the full moment problem from finite to infinite dimensions
This paper is aimed to show the essential role played by the theory of
quasi-analytic functions in the study of the determinacy of the moment problem
on finite and infinite-dimensional spaces. In particular, the quasi-analytic
criterion of self-adjointness of operators and their commutativity are crucial
to establish whether or not a measure is uniquely determined by its moments.
Our main goal is to point out that this is a common feature of the determinacy
question in both the finite and the infinite-dimensional moment problem, by
reviewing some of the most known determinacy results from this perspective. We
also collect some properties of independent interest concerning the
characterization of quasi-analytic classes associated to log-convex sequences.Comment: 28 pages, Stochastic and Infinite Dimensional Analysis, Chapter 9,
Trends in Mathematics, Birkh\"auser Basel, 201
Defining a self-evaluation digital literacy framework for secondary educators: the DigiLit Leicester project
Despite the growing interest in digital literacy within educational policy, guidance for secondary educators in terms of how digital literacy translates into the classroom is lacking. As a result, many teachers feel ill-prepared to support their learners in using technology effectively. The DigiLit Leicester project created an infrastructure for holistic, integrated change, by supporting staff development in the area of digital literacy for secondary school teachers and teaching support staff. The purpose of this article is to demonstrate how the critique of existing digital literacy frameworks enabled a self-evaluation framework for practitioners to be developed. Crucially, this framework enables a co-operative, partnership approach to be taken to pedagogic innovation. Moreover, it enables social and ethical issues to underpin a focus on teacher-agency and radical collegiality inside the domain of digital literacy. Thus, the authors argue that the shared development framework constitutes a new model for implementing digital literacy aimed at transforming the provision of secondary education across a city
Explicit formulae in probability and in statistical physics
We consider two aspects of Marc Yor's work that have had an impact in
statistical physics: firstly, his results on the windings of planar Brownian
motion and their implications for the study of polymers; secondly, his theory
of exponential functionals of Levy processes and its connections with
disordered systems. Particular emphasis is placed on techniques leading to
explicit calculations.Comment: 14 pages, 2 figures. To appear in Seminaire de Probabilites, Special
Issue Marc Yo
Employing the Metabolic âBranch Point Effectâ to Generate an All-or-None, Digital-like Response in Enzymatic Outputs and Enzyme-Based Sensors
Here, we demonstrate a strategy to convert the
graded MichaelisâMenten response typical of unregulated
enzymes into a sharp, effectively all-or-none response. We do
so using an approach analogous to the âbranch point effectâ, a
mechanism observed in naturally occurring metabolic networks
in which two or more enzymes compete for the same
substrate. As a model system, we used the enzymatic reaction
of glucose oxidase (GOx) and coupled it to a second,
nonsignaling reaction catalyzed by the higher affinity enzyme
hexokinase (HK) such that, at low substrate concentrations,
the second enzyme outcompetes the first, turning off the
latterâs response. Above an arbitrarily selected âthresholdâ substrate concentration, the nonsignaling HK enzyme saturates leading
to a âsuddenâ activation of the first signaling GOx enzyme and a far steeper doseâresponse curve than that observed for simple
MichaelisâMenten kinetics. Using the well-known GOx-based amperometric glucose sensor to validate our strategy, we have
steepen the normally graded response of this enzymatic sensor into a discrete yes/no output similar to that of a multimeric
cooperative enzyme with a Hill coefficient above 13. We have also shown that, by controlling the HK reaction we can precisely
tune the threshold target concentration at which we observe the enzyme output. Finally, we demonstrate the utility of this
strategy for achieving effective noise attenuation in enzyme logic gates. In addition to supporting the development of biosensors
with digital-like output, we envisage that the use of all-or-none enzymatic responses will also improve our ability to engineer
efficient enzyme-based catalysis reactions in synthetic biology applications
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