Learning Difficulties Among Dental Students- A Cross Sectional Study

Background: Learning difficulties also known as the learning disabilities are the conditions that impact on an individual’s ability to gain knowledge and skills. The common problem faced by dental students is learning subjects and doing practicals. Though many studies have been done on learning disabilities, this study gives detailed information on the problems faced by dental students. The main aim of this study is to create awareness on the difficulties faced by the dental students in learning the subjects and in doing practicals. An online survey was conducted among dental students to evaluate the learning difficulties. The study population are the 1st year dental students with a sample size of 100. 10 questions were circulated to the participants through an online survey link. Later the datas was analysed and made into pie charts. From this study, when asked about learning difficulties, the majority of the result shows that they have difficulty in learning that is nearly 75% and the rest felt easier. Nearly half of the students who feel difficulty in learning are trying to overcome their difficulty. From this survey, it was evident that most of the students have difficulty in learning dentistry. This study creates awareness among the students about the benefits and importance of overcoming the difficulty in learning

Mutational Analysis of residue V408 of LEDGE/p75

Lens Epithelium Derived Growth Factor (LEDGF/p75) is a human transcriptional co-activator and a dominant cellular binding partner of HIV-1 Integrase (IN). LEDGF/p75 tethers IN to the host chromatin aiding in formation of proviral DNA. This study involves generation of site directed mutations of Valine residue at position 408 and analyzing the effect of mutation upon interaction with IN. Previously characterized mutations L368A and D366A have been generated for serving as controls in pull-down analysis. The binding affinity of V408 and L368 mutants will be characterized by pull down analysis

APOPTOTIC INDUCTION POTENTIALS OF BACOPA MONERI AGAINST ORAL CANCER CELL LINE

Aim: To assess the apoptotic induction potentials of Bacopa monnieri against oral cancer cell.Objective: This research is done to find the apoptotic induction potentials of B. monnieri against oral cancer cell line.Background: The apoptosis is a process of programed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cellchanges and death. The initiation of apoptosis is tightly regulated by activation mechanisms, because once apoptosis has begun, it inevitably leadsto the death of the cell. The two best-understood activation mechanisms are the intrinsic pathway (also called the mitochondrial pathway) and theextrinsic pathway.Methods: The apoptotic induction potential of B. monnieri was studied on KB cell line by investigating the activation of caspase 3 and caspase 9.Reason: Oral cancer is a growing concern due to the changes in lifestyle. The treatment for this disease has been degraded the patient's health bycausing various side effects. An effective treatment for the long run is necessary. Usable of herbal plants can serve to be a possible and very effective remedy.Results: Apoptotic induction potentials of B. monnieri against oral cancer cell line were studied.Conclusion: Caspase 3 and caspase 9 was activated thus proving the apoptotic potential of B. monnieri.Keywords: Bacopa monnieri, oral cancer, apoptotic induction

Mutational Analysis of residue V408 of LEDGE/p75

Lens Epithelium Derived Growth Factor (LEDGF/p75) is a human transcriptional co-activator and a dominant cellular binding partner of HIV-1 Integrase (IN). LEDGF/p75 tethers IN to the host chromatin aiding in formation of proviral DNA. This study involves generation of site directed mutations of Valine residue at position 408 and analyzing the effect of mutation upon interaction with IN. Previously characterized mutations L368A and D366A have been generated for serving as controls in pull-down analysis. The binding affinity of V408 and L368 mutants will be characterized by pull down analysis

Literature Review on IOT Based Smart Security and Monitoring Devices for Agriculture

A smart way of automating farming process can be called as Smart Agriculture. By implying an automated system it possible to eliminate threats to the crops by reducing the human intervention. The major emphasize will be on providing favorable atmosphere for plants. These agricultural automated systems will help in managing and maintain safe environment especially the agricultural areas. Environment real time monitoring is an important factor in smart farming. Graphical User Interface based software will be provided to control the hardware system and the system will be entirely isolated environment, equipped with sensors like temperature sensor, humidity sensor. The controllers will be managed by a master station which will communicate with the human interactive software. The system will provide smart interface to the farmers. This smart system can increase the level of production than the current scenario. This system will realize smart solution for agriculture and efficientlysolve the issues related to farmers. The environment will not be the barrier for production and growth of any plant and can overcome the problem of scarcity of farming production

MEDICINAL VALUES OF PUTRANJIVA ROXBURGHII-A REVIEW

The evolving economic concerns and the depletion of natural sources motivate the researchers to look for various alternatives. We started utilizing the bio resources like bio-diesel that is substituted over Petro-diesel. As the needs increasing day by day, it is our responsibility to not to deplete all the resources available now and hence not making the future generation in a great risk. So the idea is to find new sources that we can utilize and to also try to utilize the natural resources around us in a useful manner. In a recent trend, there are more technologies available for utilizing bio-resources in an effective manner. One such kind of bio-resource we can utilize is Putranjiva roxburghii. The ultimate aim of this review paper is to create a limelight on the medicinal values of Putranjiva plant. This current study explains the research works done so far with Putranjiva plant in a detailed manner and also to create awareness on growing Putranjiva plant all over the world. The plant material can be utilized as Anti-oxidant, febrifuge and for anti-inflammatory activities, as biofuel, as an herbal preservative, as an Antioxidant agent and as Trypsin inhibitor. The commercial, as well as medicinal values of Putranjiva, are so attractive, that encourages the authors to write a review over this excellent plant material

Phytochemical, physicochemical, TLC, minerals analysis and in-vitro antioxidant activity of ethanolic extract of leaves of Heldigardia populifolia

The aim of present study was to investigate the preliminary phytochemical, physicochemical, TLC, minerals analysis and In-vitro antioxidant activity of leaves of ethanolic extract of Heldigardia populifolia. The preliminary phytochemical screening of ethanolic extract showed the presence of triterpenoids, flavonoids, glycosides, sterols, steroids, phenols, carbohydrates and saponins. The composition of minerals found in the leaf powder was within the permissible limits. TLC analysis of ethanol extract showed the five spots which indicate the presence of five phytoconstituents. The extractive value of ethanol was high than acetone. Ash values were within the limits. The in-vitro antioxidant activity of ethanolic extract increased with increasing the concentration. The ethanolic extract in all the concentration showed the significant antioxidant activity

Combined effect of bromelain and turmeric against acetic acid induced ulcerative colitis in wistar rats

Objective: The present study planned to study the combined effect of Bromelain and Turmeric in acetic acid induced ulcerative colitis in Wistar rats. Methodology: Wistar rats of either sex (n = 30) were divided into 5 groups. Group – I, Sham control, administered single dose of vehicle rectally; Group –II, colitis control, colitis was induced by rectal administration of single dose of 2 ml of 3%, v/v of acetic acid in 0.9% saline; Group–III, treated with Turmeric (50 mg/kg/p.o); Group–IV, treated with Bromelain (100 mg/kg/p.o) and Group –V, treated with both Turmeric (50 mg/kg/p.o) and Bromelain (100 mg /kg/p.o). Colitis was induced in all the treatment groups on first day and drug treatment was continued for 7 days. During the treatment period, Disease Activity Index (DAI) was assessed daily and on 8th day White Blood Cell (WBC) Count and Differential Leucocyte Count (DLC) was performed and on 9th day all the rats were sacrificed for the assessment of intestinal inflammation, colon myeloperoxidase (MPO) levels and Histopathology. Results obtained were analysed by one-way analysis of variance followed by Tukey’s multiple comparison test. Results: Overall changes in DAI, Inflammatory scores, WBC, DLC and MPO has shown significant improvement with Turmeric and Bromelain compared to Colitis control. However, the combined therapy has shown to be more effective in alleviating ulcerative colitis compared to individual therapies. Conclusion: The present study recommends that the combination of Turmeric and Bromelain has synergistic effect in treating ulcerative colitis

AUTONOMOUS PIPELINE ROBOT

ABSTRACT Crack inspection is an important task in the maintenance of pipe line and it is closel