Optical investigation of a cavitating flow in a 2D nozzle

International audienceIn heat engines (vehicle), cavitation plays an important role in fuel atomization mechanisms. The physics of cavitation as well as its impact on spray formation and injector efficiency are not well documented yet. Experimental investigations are required. The complexity of modern injectors and the extreme conditions of injection do not facilitate experimental investigations. In this paper, experiments are conducted in a simplified geometry. The model nozzle consists of a transparent 2D micro-channel supplied with a test-oil (ISO 4113). Velocity fields are obtained by means of a shadowgraph-like imaging arrangement using PIV components (double pulsed laser and double-frame camera). Pressure fields are obtained by interferometry coupled with a Schlieren technique

A Study of YouTube recommendation graph based on measurements and stochastic tools

International audience— The Youtube recommendation is one the most important view source of a video. In this paper, we focus on the recommendation system in boosting the popularity of videos. We first construct a graph that captures the recommendation system in Youtube and study empirically the relationship between the number of views of a video and the average number of views of the videos in its recommendation list. We then consider a random walker on the recommendation graph, i.e. a random user that browses through videos such that the video it chooses to watch is selected randomly among the videos in the recommendation list of the previous video it watched. We study the stability properties of this random process and we show that the trajectory obtained does not contain cycles if the number of videos in the recommendation list is small (which is the case if the computer's screen is small). Index Terms— Analysis of recommendation system, drift stability analysis, Youtub

Transition and control in rotating-disk boundary-layer

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ABCG2 Is Overexpressed on Red Blood Cells in Ph-Negative Myeloproliferative Neoplasms and Potentiates Ruxolitinib-Induced Apoptosis

Acknowledgments: The authors would like to thank Dominique Gien, Sirandou Tounkara, and Eliane Véra at Centre National de Référence pour les Groupes Sanguins for the management of blood samples. Funding: The work was supported by Institut National de la Santé et de la Recherche Médicale (Inserm), Institut National de la Transfusion Sanguine (INTS), the University of Paris, and grants from Laboratory of Excellence (Labex) GR-Ex, reference No. ANR-11-LABX-0051. The Labex GR-Ex is funded by the IdEx program “Investissements d’avenir” of the French National Research Agency, reference No. ANR-18-IDEX-0001. R.B. was funded by the European Union’s Horizon 2020 Research and Innovation Program under grant agreement No. 675115-RELEVANCE-H2020-MSCA-ITN-2015. M.B. was funded by Ministère de l’Enseignement Supérieur et de la Recherche at the BioSPC Doctoral School. R.B. and M.B. also received financial support from Société Française d’Hématologie (SFH) and Club du Globule Rouge et du Fer (CGRF).Peer reviewedPublisher PD

Experimental Investigation of Roughness Effects on Cavitating Flow in Diesel Injectors

International audienceIn diesel injectors, the wall roughness of the nozzle holes is thought to influence cavitation formation during the injection cycle. In order to highlight the roughness effect, an experimental setup has been designed. This setup consists of a 2D-orifice that confines a cavitating flow. Specific tools are used to control-by means of femtosecond laser-and finely characterise wall roughness, and the cavitating flow is visualised using optical techniques. The different devices are introduced and the first results are presented

Shadowgraph, Schlieren and interferometry in a 2D cavitating channel flow

International audienceCavitation plays an important role in fuel atomization mechanisms but the physics of cavitation and its impact on spray formation and injector efficiency are not well documented yet. Experimental investigations are required to support the development and the validation of numerical models and the design of tomorrow's injectors, in the context of pollutant and fuel consumption reduction. The complexity of modern injectors and the extreme conditions of injection do not facilitate experimental investigations. In this paper, experiments are conducted in a simplified geometry. The model nozzle consists of a transparent 2D micro-channel supplied with a test-oil (ISO 4113). Three different optical techniques are proposed to investigate the channel flow, with the pressure drop between upstream and downstream chambers as a parameter. A shadowgraph-like imaging technique allows the observation of cavitation inception and vapor cavities development throughout the channel. The technique also reveals the presence of density gradients (pressure or temperature) in the channel flow. However, this additional information is balanced by difficulties in image interpretation, which are discussed in the paper. In addition, a combination of Schlieren technique and interferometric imaging is used to measure the density fields inside the channel. The three techniques results are carefully analysed and confronted. These results reveal a wealth of information on the flow, with pressure waves generated by bubble collapses, turbulence in the wake of vapor cavities and bubble survival in flow regions of high pressure. Our results also show that cavitation inception is located in the shear layers between the recirculation zones and the main flow, relatively far from the inlet corner, where the pressure is minimum in average. To explain this behavior, we propose a scenario of cavitation inception based on the occurrence and the growing of instabilities in the shear layers

Blockchain competition between miners: a game theoretic perspective

International audienceWe model the competition over mining resources and over several cryptocurrencies as a non-cooperative game. Leveraging results about congestion games, we establish conditions for the existence of pure Nash equilibria and provide efficient algorithms for finding such equilibria.We account for multiple system models, varying according to the way that mining resources are allocated and shared and according to the granularity at which mining puzzle complexity is adjusted. When constraints on resources are included, the resulting game is a constrained resource allocation game for which we characterize a normalized Nash equilibrium. Under the proposed models, we provide structural properties of the corresponding types of equilibrium, e.g., establishing conditions under which at most two mining infrastructures will be active or under which no miners will have incentives to mine a given cryptocurrency

Experimental characterization of near transition region in rotating-disk boundary layer

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Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation

International audienceThe rare PEL-negative phenotype is one of the last blood groups with an unknown genetic basis. By combining whole-exome sequencing and comparative global proteomic investigations, we found a large deletion in the ABCC4/MRP4 gene encoding an ATP-binding cassette (ABC) transporter in PEL-negative individuals. The loss of PEL expression on ABCC4-CRISPR-Cas9 K562 cells and its overexpression in ABCC4-transfected cells provided evidence that ABCC4 is the gene underlying the PEL blood group antigen. Although ABCC4 is an important cyclic nucleotide exporter, red blood cells from ABCC4null/PEL-negative individuals exhibited a normal guanosine 3',5'-cyclic monophosphate level, suggesting a compensatory mechanism by other erythroid ABC transporters. Interestingly, PEL-negative individuals showed an impaired platelet aggregation, confirming a role for ABCC4 in platelet function. Finally, we showed that loss-of-function mutations in the ABCC4 gene, associated with leukemia outcome, altered the expression of the PEL antigen. In addition to ABCC4 genotyping, PEL phenotyping could open a new way toward drug dose adjustment for leukemia treatment