Alkaloids, Coumarins and Lignans from Haplophyllum Species

Although there are a number of Haplophyllum species in the world, H. acutifolium (DC.) G. Don, H. buxbaumii (Poiret) G.Don, H. buxbaumii (Poiret) G.Don, subsp. Buxbaumii, H. cappadocium Spach, H. glabrinum, H. hispanicum Sprach, H. myrtifolium Boiss., H. patavinum (L.) G. D. ON. fil., H. perforatum (M.B.) Vved., H. ptilostylum Spach, H. suaveolens (DC.) G.Don, H. telephioides Boiss., H. thesioides (Fisch ex DC.) G. Don, H. tuberculatum (Forssk.) A.Juss. and H. vulcanicum Boiss. & Heldr. were most studied and a lot of compounds isolated. Only alkaloids, coumarins and lignans of these species are mentioned in this article. In addition some volatile components of H. tuberculatum were also give

İstiklal Marşımız değiştirilemez!

Taha Toros Arşivi, Dosya No: 127-İstiklal Marşı ve MarşlarUnutma İstanbul projesi İstanbul Kalkınma Ajansı'nın 2016 yılı "Yenilikçi ve Yaratıcı İstanbul Mali Destek Programı" kapsamında desteklenmiştir. Proje No: TR10/16/YNY/010

Chemical and Biological Studies with an Aconitum and a Delphinium Species

Recently, we have investigated Aconitum cochleare Woroschin and obtained three new alkaloids cochleareine, acoleareine from the aerial parts of the plant and cochleareinine from the roots. Cochlearenine exhibited antioxidant activity against DPPH free radical scavenging assay. The cardio active effect of has also have been studied on isolated heart preparations

Alkaloids and coumarins from Ruta species

Although there are a number of Ruta species in the world, R. graveolens L., R. chalepensis L., R. montana (L.) L., R. angustifolia Pers. and R. pinnata L. fil. are the most studied. However, the first two of them have been the most extensively investigated for their chemical constituents and biological activities. They are used for their anthelmintic, diuretic, emmenagogue, and aphrodisiac properties. In dermatology, they are used against psoriasis and vitiligo, and as mycosis fungicides. In many countries, the plant extracts have been used as birth control agents

Structure elucidation of organic compounds from natural sources using 1D and 2D NMR techniques

In our continuing studies on Lamiaceae family plants including Salvia, Teucrium, Ajuga, Sideritis, Nepeta and Lavandula growing in Anatolia, many terpenoids, consisting of over 50 distinct triterpenoids and steroids, and over 200 diterpenoids, several sesterterpenoids and sesquiterpenoids along with many flavonoids and other phenolic compounds have been isolated. For Salvia species abietanes, for Teucrium and Ajuga species neo-clerodanes for Sideritis species ent-kaurane diterpenes are characteristic while nepetalactones are specific for Nepeta species. In this review article, only some interesting and different type of skeleton having constituents, namely rearranged, nor-or rare diterpenes, isolated from these species will be presented. For structure elucidation of these natural diterpenoids intensive one- and two-dimensional NMR techniques (H-1, C-13 APT, DEPT, NOE/NOESY, H-1-H-1 COSY, HETCOR, COLOC, HMQC/HSQC, HMBC, SINEPT) were used besides mass and some other spectroscopic methods. (C) 2007 Published by Elsevier B.V