31 research outputs found

    Application of a new methodology based on Eurocodes and finite element simulation to the assessment of a romanesque church

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    This work proposes a methodology, based on finite element simulation, for analyzing masonry historical structures, according to Eurocodes, that has been applied for the assessment of the Saint Sebastian church, located in Piedratajada (Zaragoza, Spain). Settlement pathologies were detected and the aim of the work is to verify the current safety level and to propose reinforcement solutions if necessary. Results confirm the effect of soil settlement and allow establish the maximum admissible value. If that value is reached, a couple of reinforcement solutions, installing sheets of steel or carbon fiber composite, are proposed and analyzed

    A Mathematical Modelling Study of Chemotactic Dynamics in Cell Cultures: The Impact of Spatio-temporal Heterogeneity

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    As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell chemotaxis waves in heterogeneous fields of chemoattractant from the underlying partial differential equation models. In particular, such chemotactic waves are not in general translationally invariant travelling waves, but possess a spatial variation that evolves in time, and may even oscillate back and forth in time, according to the details of the chemotactic gradients. The analytical framework exploits the observation that unbiased cellular diffusive flux is typically small compared to chemotactic fluxes and is first developed and validated for a range of exemplar scenarios. The framework is subsequently applied to more complex models considering the chemoattractant dynamics under more general settings, potentially including those of relevance for representing pathophysiology scenarios in microdevice studies. In particular, even though solutions cannot be constructed in all cases, a wide variety of scenarios can be considered analytically, firstly providing global insight into the important mechanisms and features of cell motility in complex spatiotemporal fields of chemoattractant. Such analytical solutions also provide a means of rapid evaluation of model predictions, with the prospect of application in computationally demanding investigations relating theoretical models and experimental observation, such as Bayesian parameter estimation

    Cell dynamics in microfluidic devices under heterogeneous chemotaxis and growth conditions: a mathematical study

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    As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell chemotaxis waves in heterogeneous fields of chemoattractant from the underlying partial differential equation models. In particular, such chemotactic waves are not in general translationally invariant travelling waves, but possess a spatial variation that evolves in time, and may even may oscillate back and forth in time, according to the details of the chemotactic gradients. The analytical framework exploits the observation that unbiased cellular diffusive flux is typically small compared to chemotactic fluxes and is first developed and validated for a range of exemplar scenarios. The framework is subsequently applied to more complex models considering the full dynamics of the chemoattractant and how this may be driven and controlled within a microdevice by considering a range of boundary conditions. In particular, even though solutions cannot be constructed in all cases, a wide variety of scenarios can be considered analytically, firstly providing global insight into the important mechanisms and features of cell motility in complex spatiotemporal fields of chemoattractant. Such analytical solutions also provide a means of rapid evaluation of model predictions, with the prospect of application in computationally demanding investigations relating theoretical models and experimental observation, such as Bayesian parameter estimation.Comment: 32 pages, 11 figure

    A new reliability-based data-driven approach for noisy experimental data with physical constraints

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    Data Science has burst into simulation-based engineering sciences with an impressive impulse. However, data are never uncertainty-free and a suitable approach is needed to face data measurement errors and their intrinsic randomness in problems with well-established physical constraints. As in previous works, this problem is here faced by hybridizing a standard mathematical modeling approach with a new data-driven solver accounting for the phenomenological part of the problem, with the aim of finding a solution point, satisfying some constraints, that minimizes a distance to a given data-set. However, unlike such works that are established in a deterministic framework, we use the Mahalanobis distance in order to incorporate statistical second order uncertainty of data in computations, i.e. variance and correlation. We develop the underlying stochastic theoretical framework and establish the fundamental mathematical and statistical properties. The performance of the resulting reliability-based data-driven procedure is evaluated in a simple but illustrative unidimensional problem as well as in a more realistic solution of a 3D structural problem with a material with intrinsically random constitutive behavior as concrete. The results show, in comparison with other data-driven solvers, better convergence, higher accuracy, clearer interpretation, and major flexibility besides the relevance of allowing uncertainty management with low computational demand

    HÁBITOS ALIMENTARIOS DE HOMBRES CON CARACTERÍSTICAS DE DISMORFIA MUSCULAR

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    El objetivo del estudio fue conocer los hábitos de alimentación de hombres con características de dismorfia muscular que asistían a gimnasios del norte de la ciudad de Mérida, Yucatán. Participaron voluntariamente 30 personas con una media de edad de 22 años. Los cuales contestaron: a dos cuestionarios un de Dismorfia Muscular  otro de  Hábitos de Alimentación, y un Registro de Alimentos de Tres Días. Los resultados mostraron que 12 participantes fueron identificados con síntomas de Dismorfia Muscular.  Entre sus hábitos alimentarios se encontró que de manera  general  presentan un alto consumo de proteínas y de lípidos en su dieta,  así como una baja ingestión de hidratos de carbono; el 50% se somete a dietas especiales utilizando suplementos para obtener un mayor desarrollo muscular, recomendados por personas que no son del área de la salud, los cuales podrían desconocer su mecanismo de acción y sus efectos negativos en el organismo. La presencia de sintomatología de Dismorfia Muscular es alta (40%) en la población de estudio, lo que hace necesario investigar más a fondo los mecanismos de instauración del problema, del consumo de suplementos y fármacos anabólicos con el propósito de establecer estrategias  de  tratamiento y prevención. Abstract The objective was to study the feeding habits of men with muscle dysmorphia characteristics attending gyms in the north of Merida, Yucatan.  Voluntarily participated 30 people with an average age of 22. And they answered the Muscle Dysmorphia Inventory and a questionnaire on eating habits, composed of four sections including the Frequency of Food Consumption and Food Registry three days. The results showed that 12 participants were identified with symptoms of muscle dysmorphia. Among their dietary habits found that generally have a high consumption of protein and fat in your diet and a low intake of carbohydrates, 50% undergo special dietary supplements are used for greater muscle development, Recommended for people who are not health area, which could ignore its mechanism of action and its negative effects on the body. The presence of symptoms is high (40%) in the study population, making it necessary to further investigate the mechanisms for setting up the problem, taking supplements and anabolic drugs in order to establish prevention strategies.  Palabras clave: hábitos alimentarios, dismorfia muscular, hombres, muscle dysmorphia

    Caracterización de la capa límite en Madrid en situaciones de estabilidad atmosférica

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    Ponencia presentada en: XX Jornadas Científicas de la AME, IX Encuentro Hispano Luso de Meteorología y el XII Congreso Latinoamericano e Ibérico de Meteorología celebrado en Zaragoza, del 5 al 7 de mayo de 2008

    The 8th-10th January 2009 snowfalls: a case of mediterranean warm advection event

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    Póster presentado en: 11th Plinius Conference on Mediterranean Storms celebrada del 7 al 11 de septiembre de 2009 en Barcelona

    Model type II regression for lagrangian validation of HF Radar velocities in the NW Iberian Peninsula

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    2 pages, 1 figure.-- MARTECH23, 10th Marine International Workshop on Marine Technology, 19-20 de Junio de 2023, Castellón de la PlanaTwo designs of lagrangian low-cost drifting buoys have been developed in order to monitor the ocean surface dynamics in the North-west Iberian Peninsula and provide ground-truth observations that can be used to assess the performance of High Frequency (HF) Radars of RAIA observatory from 2020 to 2022. Since regression model type I, which is typically used in buoy-HF radar antennas validations, does not consider the presence of errors in the observations from both instruments, regression model type II was proposed to instrument intercomparison. Furthermore, a new metric was developed to better assess both model types regressions in lagrangian validationsThe authors also would like to thank the support from projects RADAR ON RAIA (0461_RADAR ON RAIA_1_E, co- funded by the European Union through EP-INTERREG V-A España-Portugal POCTEP program) and STRAUSS (PID2019-106008RB-C21) funded by MCIN/AEI/10.13039/501100011033N

    A window to the sea: environmental indicators for coastal risk management under the RAIA observatory (NW-Iberian Peninsula)

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    ECSA 59 Using the best scientific knowledge for the sustainable management of estuaries and coastal seas, San Sebastian (Spain), 5th–8th September 2022The international RAIA Observatory (www.marnaraia.org) resulted from the effort of 12 research and academic institutions and public agencies (Spanish and Portuguese) working in the field of meteorology and oceanography. The RAIA Observatory serves the main maritime activities of the Galicia-Northern Portugal Euroregion and contributes to collaborative observational networks. Under the framework of coastal risk management, environmental indicators are fundamental tools for the evaluation and mitigation of environmental risks, showing the current state and helping to predict future changes on ecosystem health regarding environmental risks. In last years, the different partners of the RAIA Observatory have identified 38 environmental indicators, in which 12 key risks affecting the ecosystem services of the Galicia-Northern Portugal Euroregion are being evaluated. Data was analyzed and compiled by the various partners of the RAIA Observatory and the development and optimization of the environmental indicators has been done according to the specifications provided by the European Environmental Agency (EEA) and the International Panel for Climate Change (IPCC). The resulting environmental indicators are included and shared on a publicly-accessible Web service, georeferenced and accompanied by plots (https://marrisk.inesctec.pt/public/#!/indicators). So far, the current status of the indicators has allowed us to establish risk assessment protocols for the Euroregion, and identify critical gaps in a temporal and spatial coverage. The inclusion of the environmental indicators in the RAIA Observatory is of great relevance for national and international data exchange and promotes future collaborationsN
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