A NEW MULTI-OBJECTIVE ARTIFICIAL BEE COLONY ALGORITHM FOR MULTI-OBJECTIVE OPTIMIZATION PROBLEMS

Since real-world problems have multi-objective optimization problems, algorithms that solve such problems are getting more important. In this study, a new multi-objective artificial bee colony algorithm is proposed for solving multi-objective optimization problems. With the proposed algorithm, non-dominated solutions are kept in the fixed-sized archive. It has benefited from the crowding distance during the selection of elite solutions in the archive. Moreover, the onlooker bees are selected from the archive members with the proposed algorithm. It is aimed to improve the archive members with this modification. To evaluate the performance of the proposed algorithm, ZDT1, ZDT2 and ZDT3 from ZDT family of benchmark functions were used as multi-objective benchmark problems and the results were compared with MOPSO and NSGA-II algorithms. The results show that the proposed algorithm is an alternative method for multi-objective optimization problems

Retrospective comparison of flot and modified dcf as first-line chemotherapy in metastatic gastric adenocarcinoma

Background: The aim of our study was to compare the efficacy and the safety of the FLOT and the modified DCF (mDCF) regimens in patients with metastatic gastric (GC) and gastroesophageal junction (GEJ) adenocarcinoma as first-line treatment. Methods: The medical records of 72 patients were retrospectively reviewed. Survivals and hematological adverse events of the patients were examined. Factors affecting survivals were analyzed in univariate analysis. A multivariate analysis was performed with the factors contributing to survivals in univariate analysis. Results: The median PFS (mPFS) was 10.1 months (95% CI, 6.8-13.4) in the FLOT arm (n = 33) and 7.4 months (95% CI, 9.1-21.6) in the mDCF arm (n = 39) (p = 0.041). The median OS (mOS) was 12.9 months (95% CI, 9.7-16.1) in the FLOT arm and 15.4 months (95% CI, 9.1-21.6) in the mDCF arm (p = 0.622). It was found that all grade neutropenia was 51.3% vs. 72.7% (p = 0.063), febrile neutropenia was 8.3% vs. 6.3% (p = 0.743), and thrombocytopenia was 48.7% vs. 51.5% (p = 0.813) in the FLOT and mDCF arms, respectively. Anemia was 59% in the FLOT arm and 100% in the mDCF arm (p < 0.001). Grade 3-4 anemia was 7.7% in the FLOT arm and 24.2% in the mDCF arm (p = 0.052). Discussion: It was shown that the mPFS was significantly increased in the FLOT arm compared to the mDCF arm as the first-line treatment in patients with metastatic GC and GEJC. Hematological adverse events were more favorable in the FLOT arm than in the mDCF arm

Ensemble residual network-based gender and activity recognition method with signals

Nowadays, deep learning is one of the popular research areas of the computer sciences, and many deep networks have been proposed to solve artificial intelligence and machine learning problems. Residual networks (ResNet) for instance ResNet18, ResNet50 and ResNet101 are widely used deep network in the literature. In this paper, a novel ResNet-based signal recognition method is presented. In this study, ResNet18, ResNet50 and ResNet101 are utilized as feature extractor and each network extracts 1000 features. The extracted features are concatenated, and 3000 features are obtained. In the feature selection phase, 1000 most discriminative features are selected using ReliefF, and these selected features are used as input for the third-degree polynomial (cubic) activation-based support vector machine. The proposed method achieved 99.96% and 99.61% classification accuracy rates for gender and activity recognitions, respectively. These results clearly demonstrate that the proposed pre-trained ensemble ResNet-based method achieved high success rate for sensors signals. © 2020, Springer Science+Business Media, LLC, part of Springer Nature

ORTA KARADENİZ TOPLUMUNDA DENTAL ANOMALİLERİN GÖRÜLME SIKLIĞI

ÖZETAmaç: Bu çalışmanın amacı Orta Karadeniz toplumunda dental anomalilerin görülme sıklığının değerlendirilmesidir.Gereç ve Yöntem: Çalışma çeşitli dental problemlerden dolayı, tedavi olmak amacıyla Gaziosmanpaşa Üniversitesi, Diş Hekimliği Fakültesine başvuran, 15- 60 yaş arası toplam 3795 (2357 kadın, 1438 erkek) bireyin muayeneleri amacıyla rutin olarak alınmış olan, panoramik röntgen filmleri kullanılarak yapılmıştır. Filmler üzerinde; gömülü dişler, alt keser diş eksiklikleri, transpozisyona uğramış dişler ve sürnümerer dişler değerlendirilmiştir. Çalışmaya 3. molar dişler dahil edilmemiştir. Bulgular: Çalışmaya dahil edilen bireylerde, incelenen dental anomalilerin toplam görülme sıklığı %6,58 (kadın:148 birey, %6,27, erkek:102 birey, %7,09) olarak tespit edilmiştir. Bu anomaliler içerisinde gömülü diş görülme sıklığı %4,29 (kadın:101 birey, %4,28; erkek:62 birey, %4,31), alt keser diş eksikliği görülme sıklığı %1,10 (kadın:26 birey, %1,10; erkek:16 birey, %1,11), transpozisyon görülme sıklığı %0,28 (kadın:9 birey, %0,38; erkek:2 birey, %0,13) ve sürnümerer diş görülme sıklığı %0,89 (kadın:12 birey, %0,50; erkek:22 birey, %1,52) olarak belirlenmiştir. Ayrıca transmigrasyona uğramış gömülü mandibuler kanin prevalansı %0,13 (kadın:3 birey, %0,12; erkek:2 birey, %0,14) olarak tespit edilmiştir. Yapılan istatistiksel analiz sonucunda yalnızca sürnümerer dişlerin değerlendirilmesinde cinsiyetler arasında istatistiksel olarak anlamlı fark elde edilmiş, diğer anomalilerde cinsiyetler arasında istatistiksel olarak anlamlı fark tespit edilememiştir.Sonuç: Çalışmamızda incelenen dental anomaliler arasında görülme sıklığı en fazla olan anomalinin diş gömülülüğü olduğu tespit edilmiş olup, daha sonra sırasıyla alt keser diş eksikliği, sürnümerer diş ve transpozisyon gelmektedir. Diş hekimlerinin yalnızca klinik muayene ile tespit edilemeyecek dental anomaliler ile karşılaşabileceklerinin farkında olmaları ve radyografik muayenelerini ihmal etmemeleri gerekmektedir

Diagnostic Role of Intravesical Prostatic Protrusion and Visual Prostate Symptom Score in Lower Urinary Tract Symptoms in Male

INTRODUCTION: In this study, it was aimed to evaluate non-invasive, effective and low-cost diagnostic methods of bladder filling and voiding abnormalities in male patients. METHODS: Visual Prostate Symptom Score (VPSS) and the International Prostate Symptom Score (IPSS) were completed by the patients. Patients' intravesical prostatic protrusion (IPP), prostate volume, and post voiding residual urine (PVR) were measured by suprapubic ultrasound. Bladder Outlet Obstruction Number (BOON) was used to calculate urethral resistance. Patients with a BOON value above -20 were considered obstructive. RESULTS: This study included 219 male patients aged 50 years and over.The number of patients with a BOON value over -20 were 34 (obstructed) and below -20 were 61 (non-obstructed). There was a significant difference between these two groups in terms of PSA, prostate volume, IPP, Qmax, PVR, IPSS, and VPSS. It was observed that IPSS and VPSS were correlated (r=0.786, p=0.001). Obstructive (r=0.779, p=0.000) and irritative symptoms (r=0.813, p=0.000) of IPSS and VPSS were also observed to be correlated. DISCUSSION AND CONCLUSION: VPSS was found to be equivalent to IPSS in the diagnosis of lower urinary tract symptoms (p=0.001). IPP is an important, practical, and non-invasive method that correlates with IPSS, VPSS, and BOON

Dokuz Tip Mizaç Ölçeği Ergen (DTMÖ-E) Formunun Geçerlik- Güvenirliği ve Ergenlerde Dikkat Eksikliği Hiperaktivite Bozukluğu İle Mizaç Tipleri Arasındaki İlişki

The purpose of this study is developing adolescent form (11-16 years old) of Nine Types Temperament Scale (NTTS) depending on Nine Types Temperament Model (Study 1) and evaluating and searching the relationship between Attention Deficit and Hyperactivity Disorder (ADHD) and Types of NTTM (Study 2). Sample of Study I consist of 1240 students who are between 11 and 16 years old. Pilot form of the Scale which consists of 90 items is tested with confirmatory factor analysis and with convergent and discriminant validity and the last version of the measure which consist of 82 items is prepared. Basic Personality Traits Inventory (BPTI) which depends on Fife Factor Model is used for Criterion-related validation. Results show that NTTS-A is valid and reliable measure for evaluating temperament types between 11-16 years adolescents. Their fit index is calculated as χ2 /df &lt;3; SRMR, 0.06; RMSEA, 0.045; CFI, 0.909: TLI, 0901 supported to validity data. Sample of Study II consist of 56 adolescents who are diagnosed with ADHD according to DSM-IV diagnosis criteria and 56 students who does not get diagnosed with ADHD or mental retardation/medical disorder. Temperament types of participants are evaluated by the agency of Study-I and NTTS-A, which is developed appropriate for Turkish culture. Indication of the study shows that there are more NTT7 and NTT8 in NTTM types between adolescents with ADHD than the group, who are not diagnosed with ADHD. As a result, it is discussed that traits which belong to some temperament types could have a predisposing effect on emergence of ADHD, experiencing these traits extreme severely could cause a view similar to ADHD and ADHD which is a neurodevelopmental disease could interact with temperament traits of person, in that way it could illustrate ADHD clinic. Available findings support critics about that students are labelled as ADHD specially in the last years in education environment even if they have mostly not developmental problems and students are diagnosed easily with limited observations. However, it is asserted that diagnosis based on temperament, treatment and psychosocial support programmes could be formed and effects of ADHD, which is a factor interacting with temperament traits, on personality structure of adolescents on their development process, could be predicted. Our study has the feature of being the first measure developing study which is intended to evaluate temperament types of adolescents between 11-16 years old and also it is has the feature of being the first study which searches relationship between NTTM types and ADHD.Bu çalışmanın amacı, Dokuz Tip Mizaç Modeli (DTMM)’ne dayalı olarak erişkinler için geliştirilen Dokuz Tip Mizaç Ölçeğinin (DTMÖ) 11-16 yaş arası ergen formunu (DTMÖ-E) geliştirmek (Çalışma I) ve DTMM tipleri ile Dikkat Eksikliği Hiperaktivite Bozukluğu (DEHB) arasındaki ilişkiyi incelemek ve değerlendirmektir (Çalışma II). Çalışma I’in örneklemi 11-16 yaş aralığındaki 1240 öğrenciden oluşmaktadır. 90 maddeden oluşan ölçeğin pilot formu doğrulayıcı faktör analizi, yakınsak ve ayırma (diskriminant) geçerliği ile test edilmiş ve ölçeğin 82 maddelik son hali hazırlanmıştır. Ölçüt geçerliği için ise Beş Faktör Modeli’ne dayanan Temel Kişilik Özellikleri Envanteri (TKÖE) kullanılmıştır. Sonuçlar, DTMÖ-E’nin 11-16 yaş arası ergenlerin mizaç tiplerini değerlendirmede kullanılabilecek geçerli ve güvenilir bir ölçek olduğunu göstermektedir. Uyum indeksleri χ2 /df &lt;3; SRMR, 0.06; RMSEA, 0.045; CFI, 0.909: TLI, 0901 olarak geçerlik verilerini destekler nitelikte hesaplanmıştır. Çalışma II’nin örneklemi ise DSM-IV tanı ölçütlerine göre DEHB tanısı almış 56 ergen ve mental retardasyon / tıbbi rahatsızlık ve DEHB tanısı bulunmayan 56 öğrenciden oluşmaktadır. Katılımcıların mizaç tipleri, Çalışma-I ile Türk kültürüne uygun olarak geliştirilen DTMÖ-E aracılığıyla değerlendirilmiştir. Çalışmanın bulguları, DEHB’li ergenler arasında DTMM tiplerinden DTM7 ve DTM8’in DEHB tanısı almayan gruba göre daha fazla bulunduğunu göstermektedir. Sonuç olarak, bazı mizaç tiplerine ait özelliklerin DEHB ortaya çıkmasına yatkınlaştırıcı etkisinin olabileceği, bu özelliklerin aşırı şiddette yaşanmasının DEHB benzeri bir görünüm ortaya çıkarabileceği ve nörogelişimsel bir hastalık olan DEHB’in kişinin mizaç özellikleri ile etkileşerek DEHB kliniğini sergileyebileceği tartışılmıştır. Mevcut bulgular, eğitim çevrelerinde öğrencilerin özellikle son yıllarda sıklıkla gelişimsel bir sorun olmadığı halde DEHB olarak etiketlenmesi ve sınırlı gözlemlerle kolay tanı konmasıyla ilgili eleştirileri destekleyebilecek niteliktedir. Bunun yanı sıra DTMM’nin yaklaşımı sayesinde mizaç temelli tanı, tedavi ve psikososyal destek programlarının oluşturulabileceği ve mizaç özellikleriyle etkileşen bir faktör olarak DEHB’in ergenlerin gelişim süreçlerinde kişilik yapısına nasıl bir etkide bulunacağının öngörülebileceği öne sürülmektedir. Çalışmamız, Türkiye’de 11-16 yaş arasındaki ergenlerin mizaç tiplerini değerlendirmeye yönelik ilk ölçek geliştirme çalışması olmanın yanı sıra, DTMM tipleri ile DEHB arasındaki ilişkiyi inceleyen ilk çalışma olma özelliğindedir

Evaluation of patients with fibrotic interstitial lung disease: Preliminary results from the Turk-UIP study

OBJECTIVE: Differential diagnosis of idiopathic pulmonary fibrosis (IPF) is important among fibrotic interstitial lung diseases (ILD). This study aimed to evaluate the rate of IPF in patients with fibrotic ILD and to determine the clinical-laboratory features of patients with and without IPF that would provide the differential diagnosis of IPF. MATERIAL AND METHODS: The study included the patients with the usual interstitial pneumonia (UIP) pattern or possible UIP pattern on thorax high-resolution computed tomography, and/or UIP pattern, probable UIP or possible UIP pattern at lung biopsy according to the 2011 ATS/ERSARS/ALAT guidelines. Demographics and clinical and radiological data of the patients were recorded. All data recorded by researchers was evaluated by radiology and the clinical decision board. RESULTS: A total of 336 patients (253 men, 83 women, age 65.8 +/- 9.0 years) were evaluated. Of the patients with sufficient data for diag-nosis (n=300), the diagnosis was IPF in 121 (40.3%), unclassified idiopathic interstitial pneumonia in 50 (16.7%), combined pulmonary fibrosis and emphysema (CPFE) in 40 (13.3%), and lung involvement of connective tissue disease (CTD) in 16 (5.3%). When 29 patients with definite IPF features were added to the patients with CPFE, the total number of IPF patients reached 150 (50%). Rate of male sex (p<0.001), smoking history (p<0.001), and the presence of clubbing (p=0.001) were significantly high in patients with IPE None of the women <50 years and none of the men <50 years of age without a smoking history were diagnosed with IPE Presence of at least 1 of the symptoms suggestive of CTD, erythrocyte sedimentation rate (ESR), and antinuclear antibody (FANA) positivity rates were significantly higher in the non-IPF group (p<0.001, p=0.029, p=0.009, respectively). CONCLUSION: The rate of IPF among patients with fibrotic ILD was 50%. In the differential diagnosis of IPF, sex, smoking habits, and the presence of clubbing are important. The presence of symptoms related to CTD, ESR elevation, and EANA positivity reduce the likelihood of IPF

Determination of bending parameters in press brakes

Bu çalışma kapsamında öncelikle, Hardox 400 ve Paslanmaz AISI 304L yassı malzemelerin levha kalınlığı, şekillendirme boyu ve mekanik özelliklerine bağlı olarak bükme kuvvetleri ve büküm anında üst tabladaki (punch) yer değişimlerini zamana bağlı olarak tespit edebilen ve aynı zamanda şekillendirme sırasında bükülme açısının değişiminin belirlenmesine imkan veren görüntü işleme sistemlerini de içeren hidrolik abkant pres tabanlı özel bir deney düzeneğinin tasarımı (HAPDD) ve imalatı gerçekleştirilmiştir. İmalatı gerçekleştirilerek devreye alınan HAPDD'de iki farklı malzeme çeşidiyle yapılan deneylerin sonucunda bükülecek malzemenin ebatları ve mekanik özelliklerine bağlı olarak bükme kuvvetleri ve yer değiştirme miktarları tespit edilmiştir. Kuvvet-zaman ve kuvvet-yer değiştirme grafikleri her iki malzeme çeşidi için de eş zamanlı olarak çizilerek malzemelerin büküm anındaki davranışları detaylı olarak incelenmiştir. Bükme deneylerinden önce malzemelerin çekme deneyleri yapılarak malzeme mekanik özellikleri belirlenmiş ve bu değerler üretici firmaların teorik olarak verdiği özellikler ile kıyaslanmıştır. Bu değerler arasındaki farkların büküm parametrelerine etkisi incelenmiştir. Deneylerde havada büküm tekniği kullanılmıştır. Deneyler iki faklı üretici firmadan tedarik edilen yassı malzemeler ile farklı kalınlık, farklı uzunluk, farklı büküm açısı, farklı büküm hızı ve farklı kanal açıklıklarında yapılarak tüm bu parametrelerin bükme kuvvetleri ve yer değiştirme miktarlarına etkileri ortaya konmuştur. Her iki malzeme türü için büküm anındaki kuvvet ve yerdeğiştime miktarları tedarikçi firmaya, bükme hızına, bükme açısına ve bükme boyuna göre belirlenmiştir.In this study, firstly a specific hydraulic press brake based test setup (HPBTS) with image processing systems was designed and manufactured which is able to determine the bending forces and the punch displacements of Hardox 400 and Stainless AISI 304L depending on the plate thickness, plate length and mechanical properties. It is also possible to determine the change of the bending angle during forming. Experiments carried out by HPBTS were made with two different types of materials from which bending forces and displacement amounts were obtained depending on the dimensions and mechanical properties of the material. Force-time and force-displacement graphs were plotted simultaneously for both types of materials and mechanical behavior of the materials during the bending were examined in detail. Prior to the bending tests, tensile tests of the materials were carried out and the results were compared with the ones obtained from the manufacturers. The effect of the difference between these values on the bending parameters was investigated. Air bending technique was used during the experiments. Experiments were carried out with varying thickness, length, bending angle, bending velocity and channel opening values with the flat materials supplied from two different manufacturers. The effect of these parameters on the bending forces and displacement amounts were revealed. For both materials, the forces and displacements at the bending moment were determined depending on the supplier, bending speed, bending angle and bending length.Durmazlar Makine A.Ş