37 research outputs found
Climatic change and the Mediterranean
The temperature and precipitation scenarios for the Malta region developed by the Climate Research Unit of the University of East Anglia suggest that annual temperature will increase by 0.8 to 0.9°C per degree Celsius of global change and that there will be little if any change in the annual rainfall amounts around Malta. A statistical analysis of past meteorological data for Malta indicates an existing trend towards increasing extremes of temperature; namely an increase in the maximum and a decrease in the minimum temperatures. The mean annual temperature is also apparently increasing. These data also suggest a trend towards lower total annual rainfall; an increase in the atmospheric pressure; an increase in the number of days with thunderstorms; and decreases in cloud cover and the number of hours of bright sunshine. These trends suggest that a process of desertification is already occurring in Malta, and that there is an increase in the suspended particle concentration including pollutants, in the atmosphere over the island. The hydrological cycle will be significantly affected by global warming. In Malta, natural sources of freshwater account for about 37% of all potable water in the public supply and for 84% of all irrigation water. Global
warming will affect the freshwater supply through changes to relative sea level, and through changes in rainfall and evapotranspiration. A eustatic rise in sea level of around 65 ± 35 cm by the year 2100 would adversely affect the existing extraction rates from Malta's principal aquifer and make it more vulnerable to sea water intrusion. In contrast, the direct climatic effect will be less pronounced, since only a small change in local precipitation is predicted to accompany global warming. Climate is a fundamental factor influencing the nature of the soils of Malta. Since an increase in temperature with little change in the total rainfall is anticipated, evapotranspiration will increase, leading to an increase in aridity, and to soil degradation mainly due to salinization and alkalinization. The anticipated increase in temperature; a shift in precipitation patterns; a decrease in soil water availability; and a rise in sea level, will have negative impacts on agriculture, natural vegetation and associated fauna, favouring an increase in xerophilic, thermophilic and halophilic species. Such species are likely to be introduced ones, thriving at the expense of native species. It is predicted that the character of the vegetation will change from that typical of Mediterranean coastal lowlands, to associations more typical of deserts. This shift in vegetation pattern would be enhanced by soil erosion and increased soil salinity. Remedial action at a local level could include measures to prevent soil erosion by gradually changing to crops and trees that stabilize soils and which tolerate the new climatic conditions. A change in temperature could possibly lead to an increase in agricultural pests, whilst sea level rise may cause inundation of low-lying agricultural land such as that at Pwales and of groves such as those at Salina Bay. The impacts on fisheries may be less dramatic but changes in migration patterns of important fish such as lampuki might happen; and the potentially adverse effects which competitive thermophilic seaweeds may have on the important Posidonia meadows may be of concern in the future. The effects on aquaculture are difficult to assess but may include an increase in pathogens. The control of pollutants and protection of the Posidonia meadows are recommended, together with development of more sustainable use of fisheries resources. The present coastal, near-shore and freshwater ecosystems are threatened by a number of anthropogenic, non-climatic changes. Any additional impacts on these ecosystems resulting from climatic changes will have to be assessed in the light of such nonclimatic effects, if the overall projections of future changes are to be accurate. Increased eutrophic conditions and increased water stratification are likely to occur under conditions of global change in certain localities already influenced by other non-climatic human activities. Non-linear biological responses to climatic changes are discussed and may prove to be quite significant but difficult to predict with the present state of knowledge. Coastal sandy beaches, sand dunes and saline marsh habitats are considered to be sensitive to predicted climate change impacts, through increased erosion, enhanced shoreline recession and increased environmental fluctuations. The extent of impacts on such habitats, under less severe climatic change scenarios, will depend largely on present and future land-use management practices. Given the coastal topography, present drainage patterns and negligible tectonic movements in Malta, the predicted rise in sea level will have coast and especially those in the main drainage basins will become more susceptible to periodic rainfall-induced flooding and anticipatory action will be needed to address the consequential economic and social disruption. Impacts on coastal settlements are expected as a result of tidal and storm surges rather than from permanent inundation. A rise in sea level may cause sewage systems to flood, and new systems may have to be developed to reduce public health risks from such a hazard, including the increased risk of epidemics of enteric disorders such as typhoid fever. Salt water intrusion into aquifers will reduce the quantity and quality of potable water resources. Temperature rise and an increased frequency of extreme high temperatures, especially when combined with high humidity, will put some population groups such as the elderly and infants at risk from heat stress. Diseases presently confined to the tropics may spread to higher latitudes, and tropical and sub-tropical vector borne diseases may become more widespread, partly because vector survival will increase and partly because the parasites may be able to complete their life cycle more easily. Malaria may reappear in Europe, whilst Leishmaniasis, which has been under control in the recent past, already seems to be on the increase, possibly as a result of recent increases in temperature and humidity. Increased exposure to the sun when combined with possible ozone layer depletion may result in a further rise in the incidence of both melanomas and non-melanotic skin cancers. Exposure to increased ultraviolet (UV) radiation is expected to cause damage to the cornea and lens and an increased incidence of cataracts. The effect of UVB radiation on the human immune system is far less well understood, but it is a well accepted fact however, that UV, possibly acting through DNA damage, is an important precipitating factor of the auto-immune condition, systemic lupus erythematosus. The tourist industry has, for many years, been one of the Islands' most important economic activities, employing 5.8% of the total working population. If the climate conditions of the Maltese Islands change, the tourist industry could suffer, causing disruption to the Maltese economy and hardship to the population. Sea level rise will certainly have an impact on this site-dependent and coastal industry, which would be adversely affected by the loss of sandy beaches and the reduction in potable water supply. The tourist industry, is by its very nature, fragile and susceptible to political, economic and social changes. Climate change will add another element of uncertainty to this sector. Transport in Malta depends entirely on roads, whilst a ferry service connects the islands of Malta, Gozo and Comino and is also used around the Grand Harbour area. Road traffic would suffer in the event of flooding of the main traffic arteries as a result of severe rain storms, which will probably increase along with the anticipated increase in autumn precipitation. Changes in climate are expected to have an effect on the patterns of energy demand to heat and cool buildings. Electricity generation, which accounts for almost two thirds of primary energy consumption, has grown on average by about 8.5% per year in recent years. The predicted average temperature increases would, theoretically, reduce the need to provide heating, thereby saving energy. Given the low thermal performance of Maltese buildings, an increase in ambient temperature may merely result in a more thermally comfortable interior, rather than a saving of energy. · In the commercial and industrial sectors, the interhal heat generated by the use of machinery is high and an increase in ambient temperature, may result in a need for cooling through increased ventilation and possibly an extension of the air conditioning season. The introduction of thermal insulation to the building envelope, would reduce both the heating demand in winter as well as the cooling demand in summer. The displacement of fossil fuels by renewable energy sources particularly biomass and hydro power would reduce carbon dioxide emissions. In Malta there is good potential for development of solar energy, although land availability is a major obstacle. There is less possibility of harnessing wind energy on a large scale although wind energy is already widely used for water pumping in agriculture.peer-reviewe
Comparative oncology and clinical translation of glyco protein conjugated gold nano therapeutic agent (GA-198AuNP) [abstract]
Nanoscience Poster SessionAs part of our efforts toward clinical translation of GA-198AuNP, our studies are focused on therapeutic efficacy of nanoparticulate GA198AuNP agent in dogs with prostatic carcinoma. The overall goal is to gain clinical insights on therapeutic efficacy of GA198AuNP in a large animal model. We have performed a phase I clinical trial using GA-AuNP administered intravenously or intratumorally by injection or infusion. CT scans were performed prior to injection and 24 hours post injection in 3 of the 4 dogs. Following injections, dogs were allowed further treatment as recommended by the primary attending clinician. Four dogs have been treated to date. Complications related to GA-AuNP treatment were not observed, and all 4 dogs received adjunctive treatment with radiation therapy and/ or chemotherapy. These preliminary studies have clearly provided compelling evidence on the therapeutic potential of biocompatible GA-AuNP for their utility as novel therapeutic agents in treating various types of inoperable solid tumors. Intra-tumoral and intravenous administration of GA-AuNP is safe in dogs with spontaneously occurring tumors. As further therapeutic efficacy studies continue, the outcome of this clinical trial in a large animal model will generate therapeutic efficacy data which will be used for filing IND application for Phase I clinical trial studies. This clinical translation effort provides significant advances in terms of delivering optimum therapeutic payloads into prostate cancers with subsequent reduction in tumor volume, thus may effectively reduce/eliminate the need for surgical resection. This presentation will include details of clinical translation of GA198AuNP in prostate tumor bearing dogs
Time trend of Buthyl- and Phenyl-Tin contamination in organisms of the Lagoon of Venice (1999-2003)
Petroleum-Hydrocarbons In The Marine Bivalve Venus-Verrucosa - Accumulation And Cellular-Responses
Sewage pollution impact on Mediterranean rocky-reef fish assemblages
International audienceThe effects of sewage outfalls on subtidal fish assemblages were studied along the NW coasts of Malta (Sicily channel, Mediterranean Sea) by means of underwater visual census. The presence of two spatially distinct outfalls discharging untreated wastewaters allowed to use a balanced symmetrical ACI (After Control/Impact) design that consisted of two putatively impacted locations and two controls, with four sites nested in each location. Surveys were performed in 2006 at two random dates. The study highlighted significant changes at both assemblage and individual species levels. Fish assemblages structures were different between controls and sewages, where total abundance of fish were higher. The responses of individual species to sewage pollution were mostly related to an anomalous increase of two small opportunistic species i.e. and and to a decrease of species of the genus , particularly and Moreover in correspondence of the outfalls, significant changes of the fish size distribution were detected for several species. These results support the use of fish assemblages as biological indicators for marine coastal waters and demonstrated the possibility to obtain sharp signals of environmental impact from some individual fish species
Effects of pollution by petroleum hydrocarbons on the bivalve (Venus verrucosa)
SIGLEAvailable from British Library Document Supply Centre- DSC:D68394/86 / BLDSC - British Library Document Supply CentreGBUnited Kingdo