3,243 research outputs found
Emotional Strategies as Catalysts for Cooperation in Signed Networks
The evolution of unconditional cooperation is one of the fundamental problems
in science. A new solution is proposed to solve this puzzle. We treat this
issue with an evolutionary model in which agents play the Prisoner's Dilemma on
signed networks. The topology is allowed to co-evolve with relational signs as
well as with agent strategies. We introduce a strategy that is conditional on
the emotional content embedded in network signs. We show that this strategy
acts as a catalyst and creates favorable conditions for the spread of
unconditional cooperation. In line with the literature, we found evidence that
the evolution of cooperation most likely occurs in networks with relatively
high chances of rewiring and with low likelihood of strategy adoption. While a
low likelihood of rewiring enhances cooperation, a very high likelihood seems
to limit its diffusion. Furthermore, unlike in non-signed networks, cooperation
becomes more prevalent in denser topologies.Comment: 24 pages, Accepted for publication in Advances in Complex System
Freezing and Slow Evolution in a Constrained Opinion Dynamics Model
We study opinion formation in a population that consists of leftists,
centrists, and rightist. In an interaction between neighboring agents, a
centrist and a leftist can become both centrists or leftists (and similarly for
a centrist and a rightist). In contrast, leftists and rightists do not affect
each other. The initial density of centrists rho_0 controls the evolution. With
probability rho_0 the system reaches a centrist consensus, while with
probability 1-rho_0 a frozen population of leftists and rightists results. In
one dimension, we determine this frozen state and the opinion dynamics by
mapping the system onto a spin-1 Ising model with zero-temperature Glauber
kinetics. In the frozen state, the length distribution of single-opinion
domains has an algebraic small-size tail x^{-2(1-psi)} and the average domain
size grows as L^{2*psi}, where L is the system length. The approach to this
frozen state is governed by a t^{-psi} long-time tail with psi-->2*rho_0/pi as
rho_0-->0.Comment: 4 pages, 6 figures, 2-column revtex4 format, for submission to J.
Phys. A. Revision contains lots of stylistic changes and 1 new result; the
main conclusions are the sam
Neurophysiology
Contains reports on two research projects.Bell Telephone Laboratories, IncorporatedNational Institutes of HealthTeagle Foundation, IncorporatedUnited States Air Force, Aeronautical Systems Division (Contract AF33(616)-7783
Invariants from classical field theory
We introduce a method that generates invariant functions from perturbative
classical field theories depending on external parameters. Applying our methods
to several field theories such as abelian BF, Chern-Simons and 2-dimensional
Yang-Mills theory, we obtain, respectively, the linking number for embedded
submanifolds in compact varieties, the Gauss' and the second Milnor's invariant
for links in S^3, and invariants under area-preserving diffeomorphisms for
configurations of immersed planar curves.Comment: 20 pages, 1 figure, to appear in J. Math. Phy
Consistent reactive participation of group members and reduction of intergroup conflict
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68015/2/10.1177_002200275900300103.pd
Interleukin 1 induces early protein phosphorylation and requires only a short exposure for late induced secretion of beta-endorphin in a mouse pituitary cell line.
Hereditary sensory and autonomic neuropathies: types II, III, and IV
The hereditary sensory and autonomic neuropathies (HSAN) encompass a number of inherited disorders that are associated with sensory dysfunction (depressed reflexes, altered pain and temperature perception) and varying degrees of autonomic dysfunction (gastroesophageal reflux, postural hypotention, excessive sweating). Subsequent to the numerical classification of four distinct forms of HSAN that was proposed by Dyck and Ohta, additional entities continue to be described, so that identification and classification are ongoing. As a group, the HSAN are rare diseases that affect both sexes. HSAN III is almost exclusive to individuals of Eastern European Jewish extraction, with incidence of 1 per 3600 live births. Several hundred cases with HSAN IV have been reported. The worldwide prevalence of HSAN type II is very low. This review focuses on the description of three of the disorders, HSAN II through IV, that are characterized by autosomal recessive inheritance and onset at birth. These three forms of HSAN have been the most intensively studied, especially familial dysautonomia (Riley-Day syndrome or HSAN III), which is often used as a prototype for comparison to the other HSAN. Each HSAN disorder is likely caused by different genetic errors that affect specific aspects of small fiber neurodevelopment, which result in variable phenotypic expression. As genetic tests are routinely used for diagnostic confirmation of HSAN III only, other means of differentiating between the disorders is necessary. Diagnosis is based on the clinical features, the degree of both sensory and autonomic dysfunction, and biochemical evaluations, with pathologic examinations serving to further confirm differences. Treatments for all these disorders are supportive
An analog retina model for detecting dim moving objects against a bright moving background
We are interested in applications that require the ability to track a dim target against a bright, moving background. Since the target signal will be less than or comparable to the variations in the background signal intensity, sophisticated techniques must be employed to detect the target. We present an analog retina model that adapts to the motion of the background in order to enhance targets that have a velocity difference with respect to the background. Computer simulation results and our preliminary concept of an analog 'Z' focal plane implementation are also presented
Renormalization Ambiguities in Chern-Simons Theory
We introduce a new family of gauge invariant regularizations of Chern-Simons
theories which generate one-loop renormalizations of the coupling constant of
the form where can take any arbitrary integer value. In
the particular case we get an explicit example of a gauge invariant
regularization which does not generate radiative corrections to the bare
coupling constant. This ambiguity in the radiative corrections to is
reminiscent of the Coste-L\"uscher results for the parity anomaly in (2+1)
fermionic effective actions.Comment: 10 pages, harvmac, no changes, 1 Postscript figure (now included
Poly‐aneuploid cancer cells promote evolvability, generating lethal cancer
Cancer cells utilize the forces of natural selection to evolve evolvability allowing a constant supply of heritable variation that permits a cancer species to evolutionary track changing hazards and opportunities. Over time, the dynamic tumor ecosystem is exposed to extreme, catastrophic changes in the conditions of the tumor—natural (e.g., loss of blood supply) or imposed (therapeutic). While the nature of these catastrophes may be varied or unique, their common property may be to doom the current cancer phenotype unless it evolves rapidly. Poly‐aneuploid cancer cells (PACCs) may serve as efficient sources of heritable variation that allows cancer cells to evolve rapidly, speciate, evolutionarily track their environment, and most critically for patient outcome and survival, permit evolutionary rescue, therapy resistance, and metastasis. As a conditional evolutionary strategy, they permit the cancer cells to accelerate evolution under stress and slow down the generation of heritable variation when conditions are more favorable or when the cancer cells are closer to an evolutionary optimum. We hypothesize that they play a critical and outsized role in lethality by their increased capacity for invasion and motility, for enduring novel and stressful environments, and for generating heritable variation that can be dispensed to their 2N+ aneuploid progeny that make up the bulk of cancer cells within a tumor, providing population rescue in response to therapeutic stress. Targeting PACCs is essential to cancer therapy and patient cure—without the eradication of the resilient PACCs, cancer will recur in treated patients.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/156440/2/eva12929_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156440/1/eva12929.pd
- …