Availability and Feasibility of Water Desalination as Non-conventional Resource for Agricultural Irrigation in the MENA Region: A review

This is the final version. Available on open access from MDPI via the DOI in this recordMany countries in the MENA region (Middle East and North Africa) are facing water scarcity, which poses a great challenge to agricultural production. Furthermore, water scarcity is projected to increase due to climate change, particularly in arid and semi-arid regions. The integration of solar power and water desalination systems in greenhouses to overcome water shortages is one of the preferred technologies in crop-growing areas. Crop growth control is done through sufficient management of environmental climatic variables as well as the quantity and quality of water and applied fertilisers with irrigation. Numerous crops such as cucumbers, tomatoes, peppers, lettuces, strawberries, flowers, and herbs can be grown under greenhouse conditions using desalinated water. This paper displays the state of the art in (i) solar-driven saltwater desalination to irrigate crops, (ii) the feasibility of water desalination for agriculture in the MENA region, (iii) the economics and environmental impacts of the desalination process, (iv) the quality of desalinated water compared with other non-conventional water resources and (v) recommendations for the future in the MENA region.Science, Technology, and Innovation Funding Authority (STIFA) of EgyptBritish Counci

Estimation of supply and demand functions of the major food security crops in the Sudan (1974- 2004)

This study aimed at estimating the supply and demand functions and measuring the food consumption gaps of the main food crops, namely sorghum, wheat and millet. Descriptive statistics and backward regret-ssion analysis were used as tools of analysis. Results showed that the quantity of food crops produced was far below the real needs for local consumption. Moreover, self-sufficiency ratio has declined from 100 % in 1981/1982 to 72.6% in 2000 /2001, indicating positive trend in the food consumption gap. Regarding sorghum crop, results showed that the most important factor affecting the supply of sorghum was the lagged producer price whereas the most important factors affecting demand for sorghum were consumer price of sorghum and per capita income. Results showed that the most important factors affecting the supply of wheat were the producer price of sorghum and the producer price of cotton whereas the most important factor affecting demand for wheat was the consumer price of sorghum. The millet crop was affected by the lagged producer price and consumer price of millet supply and demand functions, respectively. The results of this study indicated that, in a national sense, Sudan is food insecure during the period 1980/81-2004/2005. The shift in consumption habits towards wheat is highly responsible for the food insecurity. &nbsp

The Efficacy of Na-Butyrate Encapsulated in Palm Fat on Experimentally Induced Necrotic Enteritis and Enumeration of intestinal resident Clostridium perfringens in Broiler Chickens

Abstract: Experimental induction of necrotic enteritis (NE) successfully achieved by daily oral inoculation o

Genetic analysis : therapeutic drug monitoring of metformin and glimepiride on diabetic patients’ plasma including genetic polymorphism

Diabetes is a widespread disease that needs to be controlled. Therapeutic monitoring of drugs is very helpful in maintaining desirable doses. To study a correlation between the blood level of metformin (to a lesser extent, glimepiride) and genotyping (mainly the SULT1A1 genotype). Determine drug levels using a validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) tool. A validated LC-MS/MS method was developed to determine metformin and glimepiride levels in human plasma. DNA extraction was performed using Jena Bioscience’s Blood DNA preparation, in which a column kit was used to extract DNA for genetic polymorphism. The investigation was carried out using both medications in type 2 diabetes patients alongside the genetic polymorphism. One hundred and six patients were assessed. The prevalence of homozygosity for SULT1A1 and wild-type CYP2D6 * 4 were 72.6% and 73.6%, respectively. After adjustment for daily intake of metformin, three patients out of five with the highest levels of metformin had no homozygosity (SULT1A1 genotype). Statistically, variables that demonstrated an insignificant correlation with the level of metformin were body mass index (rs (87) = 0.32, P = 0.011) and age (rs (87) =0.26, P = 0.017). The homozygous (SULT1A1 genotype) correlation was moderate (rs (87) =0.21, P = 0.052). According to the findings, patients with the wt/wt CYP2D6 genotype had considerably greater levels of endoxifen than those with the v/v CYP2D6 genotype. The study’s results reported a probable correlation between the blood level of metformin (to a lesser extent, glimepiride) and genotyping (mainly the SULT1A1 genotype). Genotype-guided drug therapy may provide a novel contribution to maximize drug efficacy and/or minimize toxicity

European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment

To develop a European guideline on pharmacologic treatment of Tourette syndrome (TS) the available literature was thoroughly screened and extensively discussed by a working group of the European Society for the Study of Tourette syndrome (ESSTS). Although there are many more studies on pharmacotherapy of TS than on behavioral treatment options, only a limited number of studies meets rigorous quality criteria. Therefore, we have devised a two-stage approach. First, we present the highest level of evidence by reporting the findings of existing Cochrane reviews in this field. Subsequently, we provide the first comprehensive overview of all reports on pharmacological treatment options for TS through a MEDLINE, PubMed, and EMBASE search for all studies that document the effect of pharmacological treatment of TS and other tic disorders between 1970 and November 2010. We present a summary of the current consensus on pharmacological treatment options for TS in Europe to guide the clinician in daily practice. This summary is, however, rather a status quo of a clinically helpful but merely low evidence guideline, mainly driven by expert experience and opinion, since rigorous experimental studies are scarce

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells.

In humans and other mammals it is known that calcium and phosphate ions are secreted from the distal small intestine into the lumen. However, why this secretion occurs is unclear. Here, we show that the process leads to the formation of amorphous magnesium-substituted calcium phosphate nanoparticles that trap soluble macromolecules, such as bacterial peptidoglycan and orally fed protein antigens, in the lumen and transport them to immune cells of the intestinal tissue. The macromolecule-containing nanoparticles utilize epithelial M cells to enter Peyer's patches, small areas of the intestine concentrated with particle-scavenging immune cells. In wild-type mice, intestinal immune cells containing these naturally formed nanoparticles expressed the immune tolerance-associated molecule 'programmed death-ligand 1', whereas in NOD1/2 double knockout mice, which cannot recognize peptidoglycan, programmed death-ligand 1 was undetected. Our results explain a role for constitutively formed calcium phosphate nanoparticles in the gut lumen and show how this helps to shape intestinal immune homeostasis

Forward-planning intensity-modulated radiotherapy technique for prostate cancer

In this study, we present an intensity-modulated radiotherapy technique based on forward planning dose calculations to provide a concave dose distribution to the prostate and seminal vesicles by means of modified dynamic arc therapy (M-DAT). Dynamic arcs (350 degrees) conforming to the beam’s eye view of the prostate and seminal vesicles while shielding the rectum, combined with two lateral oblique conformal fields (15 degrees with respect to laterals) fitting the prostate only, were applied to deliver doses of 78 Gy and 61.23 Gy in 39 fractions to the prostate and seminal vesicles respectively. Dynamic wedges (45 degrees of thick end, anteriorly oriented) were used with conformal beams to adjust the dose homogeneity to the prostate, although in some cases, hard wedges (30 degrees of thick part, inferiorly oriented) were used with arcs to adjust the dose coverage to the seminal vesicles. The M-DAT was applied to 10 patients in supine and 10 patients in prone positioning to determine the proper patient positioning for optimum protection of the rectum. The M-DAT was compared with the simplified intensity-modulated arc therapy (SIMAT) technique, composed of three phases of bilateral dynami