Catalytic properties of cesium salts of 12-molybdophosphoric acid supported on SBA-15 mesoporous silica

The Cs salt of molybdophosphoric acid CS2.5H0.5PM012O40 (CsHPM) was supported on SBA15 in the concentration of 20, 30 and 40 wt. % loadings. The structure and texture of these CsHPM/SBA-15 composites were studied by XRD, FT-IR and micro-Raman spectroscopy, BET and pore size distribution, SEM-EDS. Thermal stability was investigated by thermo gravimetric analysis (TGA), differential thermal analysis (DTA) and differential scanning calorimetry (DSC). The dehydration of ethanol was used to probe the catalytic properties of the CsHPM samples incorporated on the silica matrix. The main reaction products obtained on acid (dehydration) catalytic centres were ethylene and diethyl ether, and respectively acetaldehyde which was obtained on redox (dehydrogenation) catalytic centres

Inscriptions grecques et latines de Scythie Mineure, vol. VI. Suppléments, fascucule 2 : Tomis et son territoire

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Koinè et mobilité artisanale entre la Méditerranée et la mer Noire dans l’Antiquité. Hommage à Pierre Dupont à son 70e anniversaire

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Histria. Histoire et Archéologie en mer Noire, Volume commémoratif du centenaire de la fouille d’Histria

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Fighting The Enemy Of Fair View Principle – Getting To Know Creative Accounting

In this paper, we aim to discuss the role of creative accounting as a technique of accounts manipulation in contrast with the fundamental principle of accounting – fair view presentation, and the ethics of the accounting profession. In order to do so, we review the opinions of various authors on the subject while contrasting both fraud and professional ethics with creative accounting, and explaining the inverse causal relationship that arises between creative accounting and fair view principle. Fur-ther on, we determine what the role of auditors and corporate governance is in winning the fight over this kind of accounting practices. The study of previous literature is meant to be the basis for some possible comprehensive solutions we put forward that, from the point of view of accounts manipula-tion, would help achieve the transparency and trustworthiness that financial reporting deserves. When we propose these solutions, our main focus is on Romania. However, by extension, they could be ap-plied anywhere else.creative accounting, accounts manipulation, true and fair view, professional ethics

Designing of artificial peptides for an improved antiviral activity

© 2018 Bentham Science PublishersBackground: Few HIV-1fusion and replication inhibitors were developed, with limited clinical applications because of their short half-life, drug resistance and cross-reactivity with preexisting antibodies in HIV-infected patients. Objective: These limitations call for new strategies in the development of next anti-HIV-1 drugs. Among anti-gp41HIV-1 inhibitors, short-peptides exhibit high antiviral activity but the mechanism of action at molecular level has not been sufficiently addressed. Method: We report potent QSAR (Quantitative Structure-Activity Relationship) models, used for biological activity prediction of novel short HIV-1 gp41 inhibitor peptides in order to: (i) validate the anti-HIV-1 activity of MT-sifuvirtide, MT-SC34EK, MT-C34 and HP23, expressed as IC50fusion and IC50replication; (ii) predict inhibitory activity of SC24EK and its MT-derivative expressed as IC50resistant HIV-1 NL4-3 variant; (iii) propose new derivatives DMT-SC22EK, DMT-SC29EK and DMT-sifuvirtide through addition of aspartic acids by induced-mutagenesis; (iv) use molecular similarity established by fingerprint models to correlate molecular spatial features with predicted biological activity of newly generated inhibitors over parent compounds. Results: We obtained good QSAR statistic parameters, demonstrating that our QSAR models are able to predict biological activity of new HIV-1 inhibitors with suitable accuracy. Conclusion: Despite acknowledged drawbacks of a reduced dataset, our results may enhance the evaluation of biological activity of new and classical synthetic peptides as anti-HIV-1agents and represent a good start for further studies in developing new antiviral drugs.info:eu-repo/semantics/publishedVersio