Principais aspectos associados à conservação frigorífica da Pêra Rocha.

O progressivo aumento de volume de pêra Rocha exportado anualmente para países da Europa e fora da Europa é prova evidente de que se trata na realidade de um produto detentor de um elevado valor económico para o país, merecedor da atenção dos vários operadores que integram a fileira que se inicia no produtor e termina no consumidor. Os frutos possuem excelentes características organolépticas e uma boa aptidão para a conservação e transporte. A respectiva qualidade final depende em larga medida das técnicas aplicadas em cada uma das etapas da vida do fruto. Este trabalho tem como principal objectivo, fazer uma abordagem sucinta à problemática da conservação frigorífica da pêra Rocha, aos factores nela envolvidos, às principais alterações fisiológicas a que é vulnerável. Serão ainda apresentados alguns dos resultados mais recentes, obtidos no âmbito da investigação desenvolvida na ENFVN (Alcobaça).info:eu-repo/semantics/publishedVersio

Update of the PANCCO clinical practice guidelines for the treatment of ulcerative colitis in the adult population

Ulcerative colitis (US) is a chronic disease of unknown etiology. It is incurable and its clinical course is intermittent, characterized by periods of remission and relapse. The prevalence and incidence of the disease has been increasing worldwide. The update presented herein includes the participation of healthcare professionals, decision-makers, and a representative of the patients, all of whom declared their conflicts of interest. Answerable clinical questions were formulated, and the outcomes were graded. The information search was conducted on the Medline/PubMed, Embase, Epistemonikos, and LILACS databases, and covered grey literature sources, as well. The search was updated on November 30, 2020, with no restrictions regarding date or language. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) classification system was implemented to establish the strength of the recommendation and quality of evidence. A formal consensus was developed, based on the RAND/UCLA methodology and the document was peer reviewed. The short version of the Clinical Practice Guidelines for the Treatment of Ulcerative Colitis in the Adult Population is presented herein, together with the supporting evidence and respective recommendations. In mild-to-moderate UC, budesonide MMX is an option when treatment with 5-ASA fails, and before using systemic steroids. In moderate-to-severe UC, infliximab, adalimumab, vedolizumab, ustekinumab, and tofacitinib can be used as first-line therapy. If there is anti-TNF therapy failure, ustekinumab and tofacitinib provide the best results. In patients with antibiotic-refractory pouchitis, anti-TNFs are the treatment of choice