367 research outputs found

    El cuerpo del delito: género y políticas corporales en la literatura de detectives

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    La literatura de detectives se ha convertido en una de las principales formas de entretenimiento en el siglo XXI. Sin embargo, ha recibido escasa atención como herramienta de subversión feminista. Las mujeres y los roles de género que se representan en estos textos se han convertido en productos culturales de subversión post-moderna que cuestionan los discursos dominantes y las estructuras de poder. Este artículo explora las políticas identitarias de construcción del cuerpo y sus consecuencias para la dramatización de las detectives contemporáneas

    Editorial: The EXCEL Trial.

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    The Renin–Angiotensin–Aldosterone System and Coronavirus Disease 2019

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    The renin–aldosterone–angiotensin system (RAAS) plays an important role in the pathogenesis of coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for SARS-CoV-2 and the host’s expression of this membrane-bound protein could affect susceptibility to infection. The RAAS is an important regulator of cardiovascular physiology and ACE2 has an essential role. People with hypertension and other traits have shown to have an imbalance in ACE/ACE2 levels and reduced levels of ACE2 could enhance the risk of adverse outcome in patients with COVID-19. It has been hypothesised that the RAAS may mediate the interplay between cardiovascular disease and COVID-19 severity. Evidence shows that antihypertensive drugs that target the RAAS have no significant effect on the risk of infection and disease outcome. Variations in RAAS genes have been associated with the risk of developing hypertension and cardiovascular disease and could partly explain the heterogenous response to SARS-CoV-2 infection. This article explores the interplay between the RAAS and COVID-19, with emphasis on the possible relationship between genetic variations and disease severity

    Percutaneous mitral repair: current and future devices

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    Mitral regurgitation (MR) is the second most common valvular heart disease and its prevalence is increasing with population ageing. In the recent years we have witnessed the development of several transcatheter devices to correct MR in patients at high-risk for surgery. The majority of evidence regarding safety and efficacy of this new therapy comes from MitraClip studies. However, new alternatives on the field of valve repair have emerged with promising results. The aim of this review is to portrait the landscape of transcatheter mitral repair alternatives, from currently used devices to those that will have a role in the near future

    Air pollution and heart failure: relationship with the ejection fraction

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    To study whether the concentrations of particulate matter in ambient air are associated with hospital admission due to heart failure in patients with heart failure with preserved ejection fraction and reduced ejection fraction

    The Role of C-reactive Protein in Patient Risk Stratification and Treatment

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    Atherosclerosis is a chronic inflammatory disease. Several circulating inflammatory markers have been proposed for clinical use due to their ability to predict future cardiovascular events and may be useful for identifying people at high risk who might benefit from specific treatment to reduce this risk. Moreover, the identification of new therapeutic targets will allow the development of drugs that can help reduce the high residual risk of recurrence of cardiovascular events in patients with coronary artery disease. The clinical benefits of reducing recurrent major cardiovascular events recently shown by canakinumab and colchicine have renewed the cardiology community’s interest in inflammation as an aetiopathogenic mechanism for atherosclerosis. This review explores the use of C-reactive protein, which is the most frequently studied biomarker in this context; the concept of residual risk in primary and secondary cardiovascular prevention; and the current recommendations in international guidelines regarding the role of this inflammatory biomarker in cardiovascular risk stratification

    Manual de Administración: BD Peligrosidad

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    Fil: López Rivas, Jordán. SADIM: Sociedad Asturiana de Diversificación Minera; España.Fil: Pedreira Junco, José Ángel. SADIM: Sociedad Asturiana de Diversificación Minera; España.Fil: Avanzas, Rubén. SADIM: Sociedad Asturiana de Diversificación Minera; España.Fil: Ferpozzi, Federico Javier. SEGEMAR: Servicio Geológico Minero Argentino; Argentina.Fil: Candaosa, Norberto Gabriel. SEGEMAR: Servicio Geológico Minero Argentino; Argentina

    Modelo de Datos de Producción Cartográfica del SIGAM, Escalas 1:250.000 Y 1:100.000

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    Fil: Pedreira Júnco, Juan Ángel. SADIM: Sociedad Asturiana de Diversificación Minera; España.Fil: Ferpozzi, Federico Javier. Servicio Geológico Minero Argentino. Instituto de Geología y Recursos Minerales. Área de Sensores Remotos y SIG; Argentina.Fil: Candaosa, Norberto Gabriel. Servicio Geológico Minero Argentino. Instituto de Geología y Recursos Minerales. Área de Sensores Remotos y SIG; Argentina.Fil: García Manteca, Pilar. INDUROT: Instituto de Recursos Naturales y Ordenación del Territorio – Universidad de Oviedo; Argentina.Fil: Avanzas, Rubén. SADIM: Sociedad Asturiana de Diversificación Minera; España
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