Senior Recital: Nathan Autry tenor

Kennesaw State University School of Music presents Senior Recital: Nathan Autry, tenor.https://digitalcommons.kennesaw.edu/musicprograms/1718/thumbnail.jp

Best Practices in Training Caregivers to Implement Behavioral Interventions

It has been well documented in the literature that behavioral interventions are effective in reducing a wide variety of maladaptive behaviors such as aggression, self-injury and destructive behaviors (Allen & Warzak, 2000; Campbell, 2003). Despite the success of these interventions, they are often implemented in tightly controlled settings with third party individuals that are able to implement procedures with a high degree of integrity (Fryling, 2014). Due to the complexities of the natural environment, caregivers may be less likely to implement behavioral interventions with the same degree of integrity and have limited available time for training on procedures. Therefore, it is important to evaluate efficient and effective strategies for caregiver training. This presentation will review common challenges to caregiver training and outline procedures for caregiver training that are aimed at decreasing the time needed as well as increasing caregiver treatment integrity. Specifically, the advantages and disadvantages of didactics, role play and in vivo instruction will be discussed

Brief Home-Based Data Collection of Low Frequency Behaviors

Data-based decision making, an important component of positive behavior support, can be difficult in brief in-home therapy due to the limited amount of time a therapist has to directly observe the child. This difficulty is exacerbated when problem behavior occurs infrequently. When a therapist cannot reliably observe problem behavior, it is often necessary to rely on parental report. The current study evaluated three approaches for parental report of low frequency problem behavior: antecedent-behavior-consequence records, incident data, and interview. Each method was analyzed with clients in home-based therapy with 2-hour weekly appointments. All clients exhibited low-frequency (i.e., less than daily) and high-intensity (i.e., causes physical harm to self/others, damage to the environment, or severe decrement to family’s quality of life) problem behavior. The treatment goal for all clients was to reduce problem behavior (most commonly aggression, disruption, or self-injury). The number of instances of problem behavior captured by each method of data-collection, quality of the data (i.e., ability to detect treatment effects using the data), and therapist and parent acceptability of each measure were analyzed. Results are discussed in terms of the relative advantages and disadvantages of each measure, clinical application of the methods, and avenues for future research

Counter Anion Effect on the Photophysical Properties of Emissive Indolizine-Cyanine Dyes in Solution and Solid State

Near-infrared emissive materials with tunable Stokes shifts and solid-state emissions are needed for several active research areas and applications. To aid in addressing this need, a series of indolizine-cyanine compounds varying only the anions based on size, dipole, and hydrophilicity were prepared. The effect of the non-covalently bound anions on the absorption and emission properties of identical π-system indolizine-cyanine compounds were measured in solution and as thin films. Interestingly, the anion choice has a significant influence on the Stokes shift and molar absorptivities of the dyes in solution. In the solid-state, the anion choice was found to have an effect on the formation of aggregate states with higher energy absorptions than the parent monomer compound. The dyes were found to be emissive in the NIR region, with emissions peaking at near 900 nm for specific solvent and anion selections

Water-Soluble NIR Absorbing and Emitting Indolizine Cyanine and Indolizine Squarine Dyes for Biological Imaging

Organic dyes that absorb and emit in the near-infrared (NIR) region are potentially noninvasive, high-resolution, and rapid biological imaging materials. Indolizine donor-based cyanine and squaraine dyes with water-solubilizing sulfonate groups were targeted in this study due to strong absorptions and emissions in the NIR region. As previously observed for nonwater-soluble derivatives, the indolizine group with water-solubilizing groups retains a substantial shift toward longer wavelengths for both absorption and emission with squaraines and cyanines relative to classically researched indoline donor analogues. Very high quantum yields (as much as 58%) have been observed with absorption and emission \u3e700 nm in fetal bovine serum. Photostability studies, cell culture cytotoxicity, and cell uptake specificity profiles were all studied for these dyes, demonstrating exceptional biological imaging suitability

Ultra Bright Near‐Infrared Sulfonate‐Indolizine Cyanine‐ and Squaraine‐Albumin Chaperones: Record Quantum Yields and Applications

The design of bright, high quantum yield (QY) materials in the near-infrared (NIR) spectral region in water remains a significant challenge. A series of cyanine and squaraine dyes varying water solubilizing groups and heterocycles are studied to probe the interactions of these groups with albumin in water. Unprecedented, \u27ultra bright\u27 emission in water is observed for a sulfonate indolizine squaraine dye (61.1% QY) and a sulfonate indolizine cyanine dye (46.7% QY) at NIR wavelengths of \u3e700 nm and \u3e800 nm, respectively. The dyes presented herein have a lower limit of detection than the most sensitive dyes known in the NIR region for albumin detection by at least an order of magnitude, which enables more sensitive diagnostic testing. Additionally, biotinylated human serum albumin complexed with the dyes reported herein was observed to function as an immunohistochemical reagent enabling high resolution imaging of cellular α-tubulin at low dye concentrations