Assessment Protocol for Cognitive and Auditory Processing Skills for Clients Receiving Neurofeedback Treatment for Traumatic Brain Injury & Concussion: Literature Review

Neurofeedback has become increasingly popular in the medical world and will hopefully become more commonly used in the fields of speech-language pathology and audiology. Currently, there is a lack of a singular, baseline and progression diagnostic tool to measure a client’s cognitive and auditory processing skills once they are referred for neurofeedback treatment

Retrofit assessment of masonry buildings through simplified structural analysis

The current seismic prevention strategy is based on a unitary approach aimed at a risk mitigation, also at territorial level. The Italian guidelines for the assessment and mitigation of seismic risk of cultural heritage provides indications for the seismic analysis of protected cultural heritage, with the aim of specifying a path of knowledge, assessing the level of safety and planning possible improvements. The Italian building heritage is very vast and heterogeneous and was devastated by earthquakes due to its high vulnerability; therefore, the seismic risk mitigation also requires the availability of simple and handy analysis tools. The aim of this paper is the illustration of an easy, although approximate, procedure for the evaluation of the seismic safety index and the optimization of strengthening interventions. The procedure is applied to buildings located in the province of Caserta. The analyses are performed with reference to two types of buildings that are particularly recurrent and representative of the building heritage of this area and placed in areas with different seismic hazard

Evaluating the Effect of a Self-Healing Elastomer on the Self-Healing Properties of Asphalt Cement

Asphalt pavements exhibit an interesting behaviour when the traffic loading is removed. The chemical structure of asphalt cement lends itself to the ability to heal damage and improve the longevity of the pavement. This phenomenon was first discovered in the 1960s and makes up an interesting area of research. The area of self-healing materials has been a growing area of research for materials in general, but recently attempts have been made to improve the natural healing capabilities of asphalt cement. Other branches of science have begun using microcapsules dispersed through the matrix to distribute healing agent upon damage. Styrene Butadiene Styrene (SBS) modification of asphalt cement is already a common technology in the pavement industry, and this has inspired the idea to introduce a polymer that has self-healing properties into asphalt cement. This thesis looks at the effect of traditional elastomeric modification on the healing efficiency of asphalt cement and explore the use of a novel self-healing elastomer (SHE) to modify the asphalt cement healing properties. Data in this thesis indicates that the self-healing elastomer used here was unable to improve the healing efficiency of asphalt cement, while SBS has shown some ability to improve crack healing. SBS has also shown a great ability to improve adhesion, which may influence the cohesive healing ability of asphalt cement

Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs.

Active targeting by means of drug encapsulated nanoparticles decorated with targeting bioactive moieties represents the next frontier in drug delivery; it reduces drug side effects and increases the therapeutic index. Peptides, based on their chemical and biological properties, could have a prevalent role to direct drug encapsulated nanoparticles, such as liposomes, micelles, or hard nanoparticles, toward the tumor tissues. A considerable number of molecular targets for peptides are either exclusively expressed or overexpressed on both cancer vasculature and cancer cells. They can be classified into three wide categories: integrins; growth factor receptors (GFRs); and G-protein coupled receptors (GPCRs). Therapeutic agents based on nanovectors decorated with peptides targeting membrane receptors belonging to the GPCR family overexpressed by cancer cells are reviewed in this article. The most studied targeting membrane receptors are considered: somatostatin receptors; cholecystokinin receptors; receptors associated with the Bombesin like peptides family; luteinizing hormone-releasing hormone receptors; and neurotensin receptors. Nanovectors of different sizes and shapes (micelles, liposomes, or hard nanoparticles) loaded with doxorubicin or other cytotoxic drugs and externally functionalized with natural or synthetic peptides are able to target the overexpressed receptors and are described based on their formulation and in vitro and in vivo behaviors

Mechanical properties of traditional lime mortars

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Desconcentração industrial regional no Brasil (1985-1998) : pausa ou retrocesso?

Orientador : Wilson CanoTese (doutorado) - Universidade Estadual de Campinas, Instituto de EconomiaDoutorad