Effects of Dynamic Cycling on Motor Function, Gait, and Balance in Individuals with Parkinson\u27s Disease

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Evaluation of kinesthetic-tactual displays using a critical tracking task

The study sought to investigate the feasibility of applying the critical tracking task paradigm to the evaluation of kinesthetic-tactual displays. Four subjects attempted to control a first-order unstable system with a continuously decreasing time constant by using either visual or tactual unidimensional displays. Display aiding was introduced in both modalities in the form of velocity quickening. Visual tracking performance was better than tactual tracking, and velocity aiding improved the critical tracking scores for visual and tactual tracking about equally. The results suggest that the critical task methodology holds considerable promise for evaluating kinesthetic-tactual displays

The Effect of High-Intensity and Moderate-Intensity Exercise on Enjoyment and General Mood

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Crushed Stone Aggregate Resources of Indiana

Indiana Geological Survey Bulletin 42-HMineral aggregate is an aggregation of mineral material, such as crushed rock, expanded shale, perlite, sand and gravel, shells, or slag. It is sometimes bound with such material as cement or asphalt or is sometimes not bound for use as filter stone, flux stone, railroad ballast, riprap, or road metal. Crushed limestone and dolomite, sand and gravel, slag, perlite, and expanded shale are the main natural and fabricated aggregates currently used in Indiana. Some aggregate, such as sand and gravel, requires little or no processing and can be used almost as it is mined, but rock must be crushed and sorted into various desired sizes before it can be used. Many types of rocks can be used for crushed stone aggregate, but limestone and dolomite are used exclusively in Indiana (pl. 1). In this report crushed stone is synonymous with crushed limestone and dolomite. Each type of aggregate has a distinct advantage with respect to cost and availability or to a specific use for which one type is more suited than another. The advantages of crushed limestone and dolomite are that they can be crushed and sized to meet most specifications, the materials are clean and angular and bind well with cementing mixtures, a uniform lithologic composition can be maintained with little or no selective quarrying in many areas, and they are available at low cost in most counties in Indiana. Crushed stone is one of Indiana’s most important mineral commodities, ranking third in annual value behind coal and cement. During 1969 crushed stone production in Indiana totaled 25, 516,000 tons and was valued at $34,418,000.Indiana Department of Natural Resource

The Effect of Exercise and Different Exercise Intensities on Executive Function in College-Aged Individuals

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Decoding Complex Chemical Mixtures with a Physical Model of a Sensor Array

Combinatorial sensor arrays, such as the olfactory system, can detect a large number of analytes using a relatively small number of receptors. However, the complex pattern of receptor responses to even a single analyte, coupled with the non-linearity of responses to mixtures of analytes, makes quantitative prediction of compound concentrations in a mixture a challenging task. Here we develop a physical model that explicitly takes receptor-ligand interactions into account, and apply it to infer concentrations of highly related sugar nucleotides from the output of four engineered G-protein-coupled receptors. We also derive design principles that enable accurate mixture discrimination with cross-specific sensor arrays. The optimal sensor parameters exhibit relatively weak dependence on component concentrations, making a single designed array useful for analyzing a sizable range of mixtures. The maximum number of mixture components that can be successfully discriminated is twice the number of sensors in the array. Finally, antagonistic receptor responses, well-known to play an important role in natural olfactory systems, prove to be essential for the accurate prediction of component concentrations

Measurements of Isoprene-Derived Organosulfates in Ambient Aerosols by Aerosol Time-of-Flight Mass Spectrometry—Part 2: Temporal Variability and Formation Mechanisms

Organosulfate species have recently gained attention for their potentially significant contribution to secondary organic aerosol (SOA); however, their temporal behavior in the ambient atmosphere has not been probed in detail. In this work, organosulfates derived from isoprene were observed in single particle mass spectra in Atlanta, GA during the 2002 Aerosol Nucleation and Characterization Experiment (ANARChE) and the 2008 August Mini-Intensive Gas and Aerosol Study (AMIGAS). Real-time measurements revealed that the highest organosulfate concentrations occurred at night under a stable boundary layer, suggesting gas-to-particle partitioning and subsequent aqueous-phase processing of the organic precursors played key roles in their formation. Further analysis of the diurnal profile suggests possible contributions from multiple production mechanisms, including acid-catalysis and radical-initiation. This work highlights the potential for additional SOA formation pathways in biogenically influenced urban regions to enhance the organic aerosol burden