94 research outputs found

    U.S. Military Service Members’ Reintegration, Culture, and Spiritual Development

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    This qualitative study aims to find common themes that may suggest portrayals of former service members’ psychological development and their reintegration. We have found their cognitive dissonance from experiencing two very different cultures: the highly structured collective culture of military life and the individualistic culture of civilian life. Former service members tend to develop and maintain the strong ideology of “service to others” in civilian life as their goal or purpose of life. It became clear to us how they have reached to this ideology when we used our ethnic backgrounds and understandings as Japanese researchers who came from a society where collective well-being is highly valued. We came to the conclusion that the macroscopic as well as spiritual views would be beneficial to incorporate when counselors, support organizations, or health care providers are assisting former service members’ transition into civilian life

    Hepatitis C and the Social Hierarchy: How Stigma Is Built in Rural Communities

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    Although Hepatitis C has profound impacts on individuals living in communities, most research has been conducted in a hospital or laboratory setting. Additionally, there is a lack of research exploring the social effects of Hepatitis C in rural communities. In this qualitative study, we focus on perceptions on Hepatitis C within a rural community, describe how the local residents perceive social hierarchy within their community, and explore the process of stigma building. Informed by a grounded theory approach, we employed a snowball sampling strategy in a southern rural area to conduct in-depth, open-ended interviews. In our findings we describe how local restaurants were often utilized as places to exchange personal opinions on various community issues among the upper hierarchical members, consider the ways social hierarchy influences people’s perceptions, and explore community members’ response to the problem of ignored viral infections within the community. We found the community leaders are earning the trust by living in the community for an extended period of time; therefore, they tend to be elderly yet remain active as members of various committees. Additionally, we argue that the common view of “family-like support” in rural communities is largely a myth; it is a romanticized view of the rural living held and perpetuated by the upper-class people in the community. Therefore, instead of depending on idealized or imaginary social support, rural communities need to consider organizing a system of formal support

    Tie Formation and Cohesiveness in a Loosely Organized Group: Knitting Together

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    The purpose of this paper is to explore the elements of tie formation and group cohesiveness in a loosely organized group with no clearly stated goal, commitment, or purpose. We employed participant observation and personal interviews to discover factors related to group cohesiveness. With inductive approach based on our thick description of the study sites, such as meeting space and group conversations, we found the nature of relationships within these groups is affected by how each group was started and organized. Having an expressive leader may increase group cohesiveness in a loosely organized group, especially when the leader has a long history with the organization which confers authority as a leader. In addition, use of humor by an expressive leader enhances group cohesiveness. Finally, the arrangement of the group meeting space impacts group cohesiveness. The focus of previous studies was to examine group cohesiveness of task-oriented groups with measurable goals; however, this study compares two loosely organized groups

    Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain.

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    Post-mitotic neurons are generated from neural progenitor cells (NPCs) at the expense of their proliferation. Molecular and cellular mechanisms that regulate neuron production temporally and spatially should impact on the size and shape of the brain. While transcription factors such as neurogenin1 (neurog1) and neurod govern progression of neurogenesis as cell-intrinsic mechanisms, recent studies show regulatory roles of several cell-extrinsic or intercellular signaling molecules including Notch, FGF and Wnt in production of neurons/neural progenitor cells from neural stem cells/radial glial cells (NSCs/RGCs) in the ventricular zone (VZ). However, it remains elusive how production of post-mitotic neurons from neural progenitor cells is regulated in the sub-ventricular zone (SVZ). Here we show that newborn neurons accumulate in the basal-to-apical direction in the optic tectum (OT) of zebrafish embryos. While neural progenitor cells are amplified by mitoses in the apical ventricular zone, neurons are exclusively produced through mitoses of neural progenitor cells in the sub-basal zone, later in the sub-ventricular zone, and accumulate apically onto older neurons. This neurogenesis depends on Neuregulin 1 type II (NRG1-II)-ErbB signaling. Treatment with an ErbB inhibitor, AG1478 impairs mitoses in the sub-ventricular zone of the optic tectum. Removal of AG1478 resumes sub-ventricular mitoses without precedent mitoses in the apical ventricular zone prior to basal-to-apical accumulation of neurons, suggesting critical roles of ErbB signaling in mitoses for post-mitotic neuron production. Knockdown of NRG1-II impairs both mitoses in the sub-basal/sub-ventricular zone and the ventricular zone. Injection of soluble human NRG1 into the developing brain ameliorates neurogenesis of NRG1-II-knockdown embryos, suggesting a conserved role of NRG1 as a cell-extrinsic signal. From these results, we propose that NRG1-ErbB signaling stimulates cell divisions generating neurons from neural progenitor cells in the developing vertebrate brain

    Histochemical Characteristics of Tertiary Dentin Due to Calcium Hydroxide Paste in Rats

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    Calcium hydroxide is mainly used for dental pulp capping and it is thought that it induces hard tissue formation far better than other materials. Experimentally verifying this fact, Nishikawa et al revealed that bone-like dentin corresponding to tertiary dentin is rapidly formed when calcium hydroxide is applied directly to the pulp. Utilizing the same experimental system, histochemical study of the newly formed hard tissue (reparative dentin) was carried out and the results thereof were reported. Thick and irregular reparative dentin was formed in the pulp cavity and partial narrowing of the root canal was observed in m-CT. Histopathologically, the irregular reparative dentin increased its thickness obliterating the root canal having a diff erent Azan staining of aniline blue compared to primary dentin. Numerous cellular inclusion bodies were also trapped inside the thick dentin. Furthermore, with Schmorl’s thionine picric acid staining,thick reparative dentin was noted around the pulp cavity and dentin. The dentin was densely stained with picric acid with diff erent staining ability from the surrounding dentin. In addition, it was clearly confi rmed that many cells were trapped in reparative dentin. The results of the experiment suggest that the characteristics of the newly formed reparative dentin is comparable to tertiary dentin

    コミュニケーション リテラシー ノ シドウ ガ グループ ガクシュウ ニ オヨボス コウカ

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    Transactive dialogue is the important factor to lead deepening of the thought through the discussion in small group learning and communication literacy is required to each member of the group so that the dialogue unfold actively. In this study, we attempted to enhance communication literacy of children in homeroom activities of elementary school and to use teaching strategies to promote transfer of the literacy to subject area learning. Results of the verification of effects showed that the total of utterance time and the number of operational transaction were increased and the quality of group discussion in the class improved than before. In addition, a characteristic of the dialogue development to lead deepening of the thought in group learning was revealed from an aspect of the expression of transaction

    One-Step Detection of the 2009 Pandemic Influenza A(H1N1) Virus by the RT-SmartAmp Assay and Its Clinical Validation

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    <div><h3>Background</h3><p>In 2009, a pandemic (pdm) influenza A(H1N1) virus infection quickly circulated globally resulting in about 18,000 deaths around the world. In Japan, infected patients accounted for 16% of the total population. The possibility of human-to-human transmission of highly pathogenic novel influenza viruses is becoming a fear for human health and society.</p> <h3>Methodology</h3><p>To address the clinical need for rapid diagnosis, we have developed a new method, the “RT-SmartAmp assay”, to rapidly detect the 2009 pandemic influenza A(H1N1) virus from patient swab samples. The RT-SmartAmp assay comprises both reverse transcriptase (RT) and isothermal DNA amplification reactions in one step, where RNA extraction and PCR reaction are not required. We used an exciton-controlled hybridization-sensitive fluorescent primer to specifically detect the HA segment of the 2009 pdm influenza A(H1N1) virus within 40 minutes without cross-reacting with the seasonal A(H1N1), A(H3N2), or B-type (Victoria) viruses.</p> <h3>Results and Conclusions</h3><p>We evaluated the RT-SmartAmp method in clinical research carried out in Japan during a pandemic period of October 2009 to January 2010. A total of 255 swab samples were collected from outpatients with influenza-like illness at three hospitals and eleven clinics located in the Tokyo and Chiba areas in Japan. The 2009 pdm influenza A(H1N1) virus was detected by the RT-SmartAmp assay, and the detection results were subsequently compared with data of current influenza diagnostic tests (lateral flow immuno-chromatographic tests) and viral genome sequence analysis. In conclusion, by the RT-SmartAmp assay we could detect the 2009 pdm influenza A(H1N1) virus in patients' swab samples even in early stages after the initial onset of influenza symptoms. Thus, the RT-SmartAmp assay is considered to provide a simple and practical tool to rapidly detect the 2009 pdm influenza A(H1N1) virus.</p> </div

    Comparison of Pulmonary Involvement Between Patients Expressing Anti-PL-7 and Anti-Jo-1 Antibodies

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    Anti-PL-7 is an anti-tRNA synthetase antibody, and interstitial lung disease (ILD) is the most frequent complication of anti-PL-7-associated antisynthetase syndrome. However, the features of ILD have not been fully elucidated. The present study retrospectively compares 7 and 15 patients who were positive for anti-PL-7 and anti-Jo-1 antibodies, respectively. The features of ILD did not significantly differ between the two groups, but the ratio of lymphocytes in bronchoalveolar lavage fluid was higher in the Jo-1 than in the PL-7 group. High-resolution computed tomography revealed nonspecific interstitial pneumonia in all patients in the PL-7 group and organizing pneumonia in four of the 15 patients in the Jo-1 group. These findings suggest that pulmonary complications slightly differ between patients expressing anti-PL-7 and anti-Jo-1 antibodies. Further studies are required to clarify the features of ILD associated with PL-7

    From an “Internationalist Woman” to “Just another Asian Immigrant”: Transformation of Japanese Women’s Self-Image before and after Permanent Settlement in a Western Country

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    Young middle class Japanese women who speak English identify themselves as career-oriented “internationalist women.” They hold positive self-images; however, their self-images become convoluted with negative images as they experience changes in their lives. When they marry white males and become permanent residents in Western countries, their self-identities transform into “just another Asian immigrant” out of many. Many Japanese wives of white husbands deny their association with their compatriots when they actually do associate with other Japanese immigrant women. They also deny racial factors in their attraction to their white husbands. I argue that these behaviors are harnessed to redevelop a self-identity by renouncing the stereotypical images of Eurocentric Japanese women. This paper will describe the transformation of Japanese women’s self-images before and after permanent settlement in a Western country and the process of their redevelopment of self-identity

    U.S. military service members’ reintegration,culture,and spiritual development

    No full text
    This qualitative study aims to find common themes that may suggest portrayals of former service members’ psychological development and their reintegration. We have found their cognitive dissonance from experiencing two very different cultures: the highly structured collective culture of military life and the individualistic culture of civilian life. Former service members tend to develop and maintain the strong ideology of “service to others” in civilian life as their goal or purpose of life. It became clear to us how they have reached to this ideology when we used our ethnic backgrounds and understandings as Japanese researchers who came from a society where collective well-being is highly valued. We came to the conclusion that the macroscopic as well as spiritual views would be beneficial to incorporate when counselors,support organizations,or health care providers are assisting former service members’ transition into civilian life
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