D4, mating, values, and authenticty

In this study, we examined how the Dark Tetrad traits are correlated with higher-order social values, mating motives, and relationship authenticity

Locus of control as a mediator of the association between attachment and Covid-19 Conspiracy Beliefs; Covid-19 Anxiety

The present study investigates the relationship between the attachment styles and Covid-19 anxiety, taking into consideration the mediating role of locus of control and Covid-19 conspiracy belief

Genetic polymorphisms of Cyp19 and myostatin genes in Turkish indigenous sheep breeds

WOS: 000418954600008Growth and meat production traits are very important in sheep breeding. Cyp19 gene has a major role in reproductive activity and growth due to its function in estrogen synthesis. Another gene affecting growth traits is Myostatin (MSTN) gene, which mainly regulates skeletal muscle growth. In this study allele frequencies of genetic polymorphism in Cyp19 and Myostatin genes were identified by PCR-RFLP method in five indigenous Turkish sheep breeds, Chiose, Imroz, Kivircik, Zom and Morkaraman. Digestion of Cyp19 gene with HaeIII only revealed uncut AA genotype and digestion of MSTN with DraI also revealed only uncut AA genotype. Both loci analyzed in this study were found to be monomorphic in five Turkish indigenous sheep breeds. These highly conserved parts of the two genes can be useful for molecular evolutionary studies in sheep. Further studies regarding association analysis of Cyp19 and MSTN in sheep should be conducted.Istanbul University, Faculty of Veterinary Medicine [VET-TB-16-1, VET-TB-16-2, BEK-2016-22550, BEK-2017-24900]This study was supported by Istanbul University, Faculty of Veterinary Medicine with project numbers VET-TB-16-1, VET-TB-16-2, BEK-2016-22550 and BEK-2017-2490

Partial sequencing of ESR1 and CDK5RAP2 genes in dogs with mammary tumours

Canine mammary tumours (CMT) are among the most common canine cancer types in female dogs. Dogs provide an adaptable model system for human breast cancer studies. R is important to identify the underlying genetic basis to improve knowledge of pathways related to cancer pathogenesis in both species. In this study, we investigated CMT associated single nucleotide polymorphisms (SNP) in target regions of ESR1 and CDK5RAP2 genes. Partial sequencing of two genes in 25 cases with mammary tumours and 10 dogs with healthy mammary glands was performed. Two previously reported SNPs in ESR1 gene and one previously reported SNP and two novel SNPs were genotyped downstream CDK5RAP2 gene. According to the association analysis performed in cases and controls, no statistically significant association was found between these SNPs and CMTs. Comparison of the results from other studies revealed the genetic heterogeneity of ESR1 and CDK5RAP2 between different dog breeds. Larger datasets of different breeds should be analyzed in further studies to identify the possible effects of the two genes in mammary tumour development