Pre-operative Serum CEA and CA19-9 Levels in Patients with Gastric Cancer: A Single-Center Experience

Introduction: To evaluate the preoperative CEA and CA19-9 levels and their association with clinicopathologic features and mortality. Methods: This retrospective study was conducted on patients who underwent gastric surgery due to gastric adenocarcinoma from 2008 to 2015. Preoperative serum CEA and CA19-9 levels were compared according to the TNM classification and survival data were compared. Results: A total of 335 patients were included in the study with the mean age of 66.1±11.0 years. CEA and CA19-0 positivity were 29.1% and 28.1%, respectively. According to the CEA groups, T stages of the cases were statistically significant (p = 0.013). The rates of T stage 1 in group 1 (CEA positive) were significantly higher than the group 2 (CEA negative) (p=0.007). According to the CA19-9 positivity; rate of stage 2 was significantly higher in the group 1 (CA19-9 positive) (p=0.001); however, rates of stage 2 and 3 were significantly higher in the group 2 (CA19-9 negative) (p=0.004 and p=0.007, respectively). Mortality information could be accessed for 309 cases and 108 deaths (36%) were observed. The mean survival time was 45.21±2.42 months. No significant difference was observed between the groups (p>0.05). Conclusion: Patients with higher levels of CEA and CA19-9 seem to have higher grades of gastric cancer. However, CEA and CA19-9 level does not seem to be in association in our study population

MTHFR C677T mutasyonunun neden olduğu süperior mezenterik ven trombozu

Amaç: Akut süperior mezenterik ven trombozu, tüm mezenterik iskemik olayların yaklaşık % 5 -15’ini oluşturan nadir görülen bir intestinal iskemi nedenidir. Bu yazıda süperior mezenterik ven trombozu gelişen kalıtsal trombofilili 2 hastanın sunulması amaçlanmıştır. Olgu sunumu: Otuz bir ve 51 yaşında iki hastaya akut batın, mezenter iskemi nedeni ile laparotomi ve ince barsak rezeksiyonu yapıldı. Genetik incelemede her iki hastada homozigot MTHFR C677-T mutasyonu saptandı. Ameliyat sonrası dönem sorunsuz geçen hastalar 10. ve 12. günde taburcu edildi. Sonuç: Akut süperior mezenterik ven trombozu mortalitesi yüksek olan ciddi bir sağlık problemidir. Doğru tanı koyabilmek için hastalıktan şüphelenmek oldukça önemlidir. Nekroz varlığında acil eksplorasyon ve nekrotik dokuların rezeksiyonu gerekmektedir. Trombofilili hastalar tanınmalı ve uzun dönem antikoagülan kullanımı planı yapılmalıdı

Anorectal Malignant Melanoma: Retrospective Analysis of Six Patients and Review of the Literature

Malignant melanomas are rare aggressive tumours originating from the pigment-producing melanocytes. In our study, a review of the literature and a retrospective analysis of patients undergoing surgery at our clinic due to anorectal malignant melanoma were performed. The information of 6 patients undergoing surgery in our clinic due to anorectal malignant melanoma between January 2010 and January 2018 was retrieved retrospectively. The patients were assessed regarding demographic data, physical examination and imaging findings, the surgical method performed, postoperative complication, histopathological findings, oncological treatment and follow-up results. Four of the patients were female and 2 were male and the mean age was 61.6 (46–83) years. Two patients (33%) had liver metastases at the time of initial presentation. Abdominoperineal resection (APR) was performed in all patients 3 with laparoscopic method. The mean length of hospital stay was recorded to be 6.5 ± 1 days (5–12 days). Adjuvant chemotherapy and radiotherapy were administered in all patients. Also, interferon treatment was administered in one patient additionally. During the follow-up, 4 patients died due to extensive metastatic disease determined approximately in the 13th month. Two patients with regular follow-up are well and free of disease and their mean postoperative lifetime has been determined to be 12.5 months (6–26 months). Anorectal malignant melanomas (ARMM) are rare but aggressive tumours. The treatment should be focused on minimizing morbidity and maximizing the quality of life and function while removing the gross tumour

Farklı tuz konsantrasyonlarının Macar fiğ (Vicia pannonica Crantz.) çeşitlerinin çimlenme özelliklerine etkileri

This research was carried out in the Mustafa Kemal University, Faculty of Agriculture, Department of Field Crops. It was used two Hungarian vetch cultivars (Altinova-2002 and Anadolu Pembesi-2002) and five salt concentrations (unsalted/0, 50 mM, 100 mM, 150 mM, 200 mM) as treatment. In this experiment, it was estimated germination rate (%), germination index and mean germination time (day) by using germination parameters and was also measured root and shoot length (mm) and seedling fresh weight (g). Salt concentrations negatively affected evaluated features for both cultivars in the final of this research. As the salt concentrations increased, all investigated properties except mean germination time were observed to decrease. In terms of germination rate, germination index, root and shoot length and seedling fresh weight between cultivars, Altionva-2002 cultivar gave higher value than Anadolu Pembesi-2002 cultivar. When we examined Cultivar x dose interactions, all properties were most affected adverse in the Anadolu Pembesi x 200 mM interaction This research clearly showed that the cultivation of Hungarian vetches of Anadolu Pembesi and Altınova-2002 will be affected in the soil that has been exposed to the problem of salinity.Bu araştırma Mustafa Kemal Üniversitesi Ziraat Fakültesi Tarla Bitkileri Bölümünde yürütülmüştür. Çalışmada iki adet Macar fiği çeşidi (Altınova-2002 ve Anadolu Pembesi-2002) ve 5 adet tuz konsantrasyonu (kontrol, 50 mM, 100 mM, 150 mM ve 200 mM) uygulama olarak kullanılmıştır. Uygulamalar sonucunda; çimlenme oranı, çimlenme indeksi ve ortalama çimlenme süresi hesaplamıştır. Ayrıca radikula ve plumula uzunlukları ile fide yaş ağırlıkları ölçülmüştür. Araştırma sonucunda, tuz konsantrasyonları değerlendirilen tüm özellikleri olumsuz etkilemiştir. Tuz konsantrasyonu arttıkça ortalama çimlenme süresi dışında tüm özelliklerin ölçülen değerlerinin azaldığı gözlemlenmiştir. Çeşitler arasında çimlenme oranı, çimlenme indeksi, radikula ve plumula uzunluğu ve fide yaş ağırlığı özellikleri açısından, Altınova-2002 çeşidi Anadolu Pembesi-2002 çeşidinden daha toleranslı bulunmuştur. Çeşit x Doz interaksiyonları değerlendirildiğinde, tüm özellikler en fazla Anadolu Pembesi x 200 mM interaksiyonunda negatif yönde etkilenmiştir. Bu çalışma, tuzluluk problemi ile karşı karşıya kalmış topraklarda Macar fiğ tarımında Altınova-2002 ve Anadolu Pembesi çeşitlerinin olumsuz etkileneceğini açık bir şekilde göstermiştir

Effects of salinity stress on emergence and seedling growth parameters of some maize genotypes (Zea mays L.)

Maize is a very important cereal all over the world and generally cultivated in irrigated agricultural areas. Salinity affects adversely maize productivity in these areas. Maize is known as a salt sensitive species. The salt tolerance level identification in the large genetic resources and breeding populations is an important research topic for solving the salinity problem. The effects of NaCl stress on germination and seedling growth of fifteen maize genotypes were investigated in this study. Electrical conductivity (EC) values of the NaCl were settled 0 (distilled water), 4, 6, 8, 10 and 12 dS m-1 . This investigation was performed as factorial arrangement of completely randomized design with four replications. Analysis of variance (ANOVA) showed that genotypes, salinity levels and interaction between genotype x salinity were significant for all the investigated treatments emergence index (EI), root dry weight (RDW), shoot dry weight (SDW), root length (RL), shoot length (SL), and salt tolerance indexes (STI). Results also revealed that the highest reduction in emergence index (59.7%) were obtained in the highest level (12 dS m-1 ) of salinity. The results further revealed that the cultivars named DKC 6589, PR31G98, and PR31A34 were the most tolerant genotypes than the others under NaCI stress.Maize is a very important cereal all over the world and generally cultivated in irrigated agricultural areas. Salinity affects adversely maize productivity in these areas. Maize is known as a salt sensitive species. The salt tolerance level identification in the large genetic resources and breeding populations is an important research topic for solving the salinity problem. The effects of NaCl stress on germination and seedling growth of fifteen maize genotypes were investigated in this study. Electrical conductivity (EC) values of the NaCl were settled 0 (distilled water), 4, 6, 8, 10 and 12 dS m-1 . This investigation was performed as factorial arrangement of completely randomized design with four replications. Analysis of variance (ANOVA) showed that genotypes, salinity levels and interaction between genotype x salinity were significant for all the investigated treatments emergence index (EI), root dry weight (RDW), shoot dry weight (SDW), root length (RL), shoot length (SL), and salt tolerance indexes (STI). Results also revealed that the highest reduction in emergence index (59.7%) were obtained in the highest level (12 dS m-1 ) of salinity. The results further revealed that the cultivars named DKC 6589, PR31G98, and PR31A34 were the most tolerant genotypes than the others under NaCI stress

Farklı tuz konsantrasyonlarının Macar Fiğ (Vicia pannonica Crantz.) çeşitlerinin çimlenme özelliklerine etkileri

This research was carried out in the Mustafa Kemal University, Faculty of Agriculture, Department of Field Crops. It was used two Hungarian vetch cultivars (Altinova-2002 and Anadolu Pembesi-2002) and five salt concentrations (unsalted/0, 50 mM, 100 mM, 150 mM, 200 mM) as treatment. In this experiment, it was estimated germination rate (%), germination index and mean germination time (day) by using germination parameters and was also measured root and shoot length (mm) and seedling fresh weight (g). Salt concentrations negatively affected evaluated features for both cultivars in the final of this research. As the salt concentrations increased, all investigated properties except mean germination time were observed to decrease. In terms of germination rate, germination index, root and shoot length and seedling fresh weight between cultivars, Altionva-2002 cultivar gave higher value than Anadolu Pembesi-2002 cultivar. When we examined Cultivar x dose interactions, all properties were most affected adverse in the Anadolu Pembesi x 200 mM interaction This research clearly showed that the cultivation of ungarian vetches of Anadolu Pembesi and Altınova-2002 will be affected in the soil that has been exposed to the problem of salinity.Bu araştırma Mustafa Kemal Üniversitesi Ziraat Fakültesi Tarla Bitkileri Bölümünde yürütülmüştür. Çalışmada iki adet Macar fiği çeşidi (Altınova-2002 ve Anadolu Pembesi-2002) ve 5 adet tuz konsantrasyonu (kontrol, 50 mM, 100 mM, 150 mM ve 200 mM) uygulama olarak kullanılmıştır. Uygulamalar sonucunda; çimlenme oranı, çimlenme indeksi ve ortalama çimlenme süresi hesaplamıştır. Ayrıca radikula ve plumula uzunlukları ile fide yaş ağırlıkları ölçülmüştür. Araştırma sonucunda, tuz konsantrasyonları değerlendirilen tüm özellikleri olumsuz etkilemiştir. Tuz konsantrasyonu arttıkça ortalama çimlenme süresi dışında tüm özelliklerin ölçülen değerlerinin azaldığı gözlemlenmiştir. Çeşitler arasında çimlenme oranı, çimlenme indeksi, radikula ve plumula uzunluğu ve fide yaş ağırlığı özellikleri açısından, Altınova-2002 çeşidi Anadolu Pembesi-2002 çeşidinden daha toleranslı bulunmuştur. Çeşit x Doz interaksiyonları değerlendirildiğinde, tüm özellikler en fazla Anadolu Pembesi x 200 mM interaksiyonunda negatif yönde etkilenmiştir. Bu çalışma, tuzluluk problemi ile karşı karşıya kalmış topraklarda Macar fiğ tarımında Altınova-2002 ve Anadolu Pembesi çeşitlerinin olumsuz etkileneceğini açık bir şekilde göstermiştir

Talking about the Vaccine after the Pandemic: A Cross-Sectional Study among Youth in Turkey and Ethical Issues

Examining the factors that affect the vaccination rate among young people in an ethical frame can support vaccination promotion. Therefore, this study will elaborate, through an ethical lens, on young people’s hesitation about and decisions regarding getting vaccinated. The cross-sectional study was conducted with 2428 people aged 15–30 in Turkey in June 2022. The questionnaire included the following subtitles: psycho-social situation, health services and health policies, COVID-19 vaccine, and predictions about life and health after the pandemic. The average age was 22.9 years. In the study sample, 80% were vaccinated, while 20% were not. Vaccinated participants acted more cautiously to protect their health. Receiving accurate and sufficient information on proposed vaccines affects vaccination status. The primary reason for getting vaccinated was “to protect their health, families, and relatives”, and the primary reason for not getting vaccinated was “not trusting the vaccine content or the country where the vaccine was produced”. Specifically, those vaccinated felt more relaxed physically, psychologically, and socially. In addition, the expectations for the future of those vaccinated were significantly higher. Accurate and adequate information is essential for reducing vaccine hesitancy. In addition, promoting prosocial behaviors in young people and highlighting related values will support vaccination

Ankara Klübü Derneği

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2014.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Özer, Abdürrahim

Plant density and mixture ratio effects on the competition between common vetch and wheat

Mixtures of annual forage legumes with winter small grains for forage are practiced traditionally in the Mediterranean countries. The aim of the present study was to investigate the effects of variable seed mixture rates and different plant densities on the forage yield. The study also investigated the competition effects among mixture partners in the mixture of common vetch (Vicia sativa L.) and wheat (Triticum aestivium L.). Field trials were conducted at two locations (L1, Hatay and L2, Adana) during the 2008-09 and 2009- 10 growing seasons. Three plant densities (200, 400, 600 plants m-2) and five seed mixture ratios (100 % V, 75% V + 25% W, 50% V + 50% W, 25% V + 75% W, 100 % W) of common vetch (V) and wheat (W) were used. The results of the study showed that increased plant density in the mixture resulted in increased dry matter yield per unit area. In addition, increased seed ratio of wheat in the mixture caused increased dry matter yield per unit area. Also, elevated dry matter yield resulted in increased crude protein yield. Land equivalent ratio (LER), aggressivity (A) and competitive ratio (CR) indexes showed that common vetch was the dominant species in all common vetch-wheat mixtures