140 research outputs found
Are We There Yet? A Communications Evaluation Guide
Most foundation and nonprofit communicators can speak at length about the work they do and what it's intended to achieve. But when it comes to describing exactly what their efforts are achieving, few can offer specifics.This guide helps foundation and nonprofit communicators learn whether their communications are effective and what is being achieved -- and determine if any course corrections are necessary.Among the reasons stressed for evaluating communication efforts are these:Evaluation improves the effectiveness of communications.Evaluation can help organizations more effectively engage with intended audiences.Situations change - strategies and tactics may need to change as well.Evaluation ensures wise allocation of resources.The guide points out that evaluation need not be limited to large-scale campaigns or major outreach activities, but should also conducted for efforts to raise awareness of an organization or an issue. And once an evaluation is underway, the guide suggests findings be shared with those who may benefit from what is learned, such as team members, the board, colleagues and peers.The guide includes:Background on why evaluation can contribute to good communications.Four case studies of evaluation in action from the Lumina Foundation for Education, the Robert Wood Johnson Foundation, the Neimand Collaborative, and the California HealthCare Foundation.A worksheet for creating an evaluation plan
Effect of zinc on protein-energy malnutrition
Many of the clinical symptoms of protein-energy malnutrition (PEM) also occur in zinc deficiency. Studies show that zinc deficiency often accompanies kwashiorkor--a form of PEM. This raises the possibility of the PEM syndromes being a mixture of both protein and zinc deficiency symptoms;Four studies were done with male Wistar rats. The effects of dietary protein level and moderate zinc deficiency on PEM symptoms were examined;Regression analyses showed that PEM was initiated solely by protein deficiency. Loss of appetite and body weight were first symptoms. About two weeks later, dietary zinc deficiency caused further loss of appetite and body weight as zinc was depleted;Edema, moisture accumulation in liver (i.e., hepatomegaly), hypoalbuminaemia and mortalities were due primarily to protein deficiency;Elevated Na(\u27+) and Fe(\u27++) due to dietary zinc deficiency were seen only in the brain in both control and PEM rats, suggesting that brain disorders of PEM may be due to zinc deficiency;Excess dietary zinc appeared toxic to the PEM rats. It caused deaths significantly earlier in one study. Recovery from PEM was slower in rats fed excess zinc. Excess dietary zinc gave greater zinc absorption in PEM. However, this was significantly less efficient than absorption in control rats;Low dietary zinc caused increased tissue Na(\u27+) and vice versa. Damage to the sodium pump by zinc deficiency may be responsible. Similar relationships were seen for zinc and iron;A high incidence of eye disorders occurred in PEM rats fed zinc deficient diets. Possibly, most xerophthalmia in PEM is related to zinc deficiency;The moderate zinc deficiency did not significantly change plasma alkaline phosphatase concentrations
Analysing the influence of health insurance status on peoples' health seeking behaviour in rural Ghana
This paper examines the influence of health insurance status on healthcare use in rural Ghana using 286 sampled respondents from four rural communities in the Bekwai Municipality. Data were obtained using structured interview and Pearson's Chi square and bivariate regressions were used to analyse data. The results show low healthcare utilization among study participants, with most respondents having irregular use (43.5%) or rare use (43.3%). Respondents with health insurance utilized healthcare more than those without health insurance, the results being statistically significant (df = 4; n = 283, p = 0.000). The bivariate analysis revealed that health insurance status has a positive and significant influence on utilization (β = 1.284; p value = 0.000). The study recommends promotion and improvement of services of the National Health Insurance Scheme as effective strategy to improve healthcare consumption by the rural people. The expansion of health insurance services to all sections of the population is also recommended
Evaluation of analytical errors in a clinical chemistry laboratory: a 3 year experience
Background: Proficient laboratory service is the cornerstone of modern healthcare systems and has an impact on over 70% of medical decisions on admission, discharge, and medications. In recent years, there is an increasing awareness of the importance of errors in laboratory practice and their possible negative impact on patient outcomes. Aim: We retrospectively analyzed data spanning a period of 3 years on analytical errors observed in our laboratory. The data covered errors over the whole testing cycle including pre‑, intra‑, and post‑analytical phases and discussed strategies pertinent to our settings to minimize their occurrence. Materials and Methods: We described the occurrence of pre‑analytical, analytical and post‑analytical errors observed at the Komfo Anokye Teaching Hospital clinical biochemistry laboratory during a 3‑year period from January, 2010 to December, 2012. Data were analyzed with Graph Pad Prism 5(GraphPad Software Inc. CA USA). Results: A total of 589,510 tests was performed on 188,503 outpatients and hospitalized patients. The overall error rate for the 3 years was 4.7% (27,520/58,950). Pre‑analytical, analytical and post‑analytical errors contributed 3.7% (2210/58,950), 0.1% (108/58,950), and 0.9% (512/58,950), respectively. The number of tests reduced significantly over the 3-year period, but this did not correspond with a reduction in the overall error rate (P = 0.90) along with the years. Conclusion: Analytical errors are embedded within our total process setup especially pre‑analytical and post‑analytical phases. Strategic measures including quality assessment programs for staff involved in pre‑analytical processes should be intensified.Keywords: Errors, Post‑analytical, Pre‑analytical Quality contro
Alcohol, tobacco and drug use among adults experiencing homelessness in Accra, Ghana : a cross-sectional study of risk levels and associated factors
Background: Substance use contributes to poor health and increases the risk of mortality in the homeless population. This study assessed the prevalence and risk levels of substance use and associated factors among adults experiencing homelessness in Accra, Ghana. Methods: 305 adults currently experiencing sheltered and unsheltered homelessness in Accra aged > 18 years were recruited. The World Health Organization’s (WHO) Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) was used to assess substance use risk levels. Association of high-risk substance use with sociodemographic, migration, homelessness, and health characteristics were assessed using logistic regression. Results: Nearly three-quarters (71%, n = 216) of the sample had ever used a substance, almost all of whom engaged in ASSIST-defined moderate-risk (55%) or high-risk (40%) use. Survivors of physical or emotional violence (AOR = 3.54; 95% confidence interval [CI] 1.89–6.65, p<.001) and sexual violence (AOR = 3.94; 95%CI 1.85–8.39, p<.001) had significantly higher odds of engaging in high-risk substance use, particularly alcohol, cocaine, and cannabis. The likelihood of engaging in high-risk substance use was higher for men than women (AOR = 4.09; 95%CI 2.06–8.12, p<.001) but lower for those in the middle-income group compared to low-income (AOR = 3.94; 95%CI 1.85–8.39, p<.001). Conclusions: Risky substance use was common among adults experiencing homelessness in Accra, and strongly associated with violent victimisation, gender, and income levels. The findings highlight the urgent need for effective and targeted preventive and health-risk reduction strategies to address risky substance use in the homeless population in Accra and similar cities within Ghana and sub-Sahara Africa with a high burden of homelessness
Evaluation of cooperative projects supported by the International Development Research Centre
Document is also no. 50 of "Cooperative programs : a review of definition, past performance and reporting principles" (ARCHIV 107220
Interplay of adipokines in the pathogenesis of essential hypertension: A comparative cross-sectional in Ghana
Background: The renin-angiotensin-system (RAS), endothelial dysfunction and sympathetic nervous system are mechanistic risk factors of hypertension. The study sought to elucidate the interplay of adipokines in the pathogenesis of essential hypertension.Methodology: This comparative cross-sectional study recruited 200 confirmed hypertensive patients from the KATH and 50 age-matched normotensives. Participants’ blood pressures, anthropometric and socio-demographic information were voluntarily obtained. Serum levels of adiponectin, leptin and resistin of the participants were quantified using the ELISA. Renal function, lipid profile and glycemic status of all subjects were also analyzed.Results: Hypertensive patients showed a significantly higher anthropometric indices of adiposity compared to normotensives, CI (p < 0.0001), BAI (p < 0.0001) and AVI (p = 0.002). Adiponectin levels (p < 0.0001) were significantly lower in the hypertensive relative to the normotensives. Furthermore, significantly higher concentrations of serum leptin (p = 0.016) and the leptin-adiponectin ratio (p = 0.001) were observed among the hypertensive compared to the normotensives. The study further observed a direct association between serum leptin and weight (r = 0.111, p = 0.022), BMI (r = 0.129, p = 0.009) and WHtR (r = 0.098, p = 0.045) but inverse relationship with height (r = -0.134, p = 0.006) among the hypertensive. Serum leptin has a significant negative correlation with HDL-C among the hypertensive (r = -0.174, p = 0.013). The fully aOR for hypertension as predicted by resistin and adiponectin were 1.12 (95% Cl, 1.02–1.25); p = 0.019) and 0.93 (95% Cl, 0.91–0.95); p = 0.0001) respectively.Conclusion: We found that elevations in serum levels of leptin and resistin, and low levels of adiponectin may play a role in the pathogenesis of essential hypertension. Therefore, adipokines may offer themselves as potential indices for early and accurate detection of high blood pressure. At the same time our presentresults also confirm the conclusions with respect to correlation of leptin and obesity. Further longitudinal studies in a larger population are warranted to investigate the physiological and pathological functions of adipokines in hypertension.Keywords: Adipokines, Hypertension, Leptin, Adiponectin, Resisti
Micronutrient fortified condiments and noodles to reduce anemia in children and adults : a literature review and meta-analysis
Micronutrient deficiencies impose a considerable burden of disease on many middle and low income countries. Several strategies have been shown to be effective in improving micronutrient deficiencies. However, the impact of fortified condiments as well as fortified noodles is less well documented. We aimed to investigate existing evidence on the impact of micronutrient fortified condiments and noodles on hemoglobin, anemia, and functional outcomes in children and adults (age: 5 to 50 years). We conducted a literature review in electronic databases. In addition, we screened the homepages of relevant organizations and journals. We included randomized controlled trials (RCT). Of 1046 retrieved studies, 14 RCT provided data for the meta-analysis. Micronutrient fortification of condiments and noodles increased hemoglobin concentrations by 0.74 g/dL (95%-confidence intervals (95%-CI): 0.56 to 0.93; 12 studies) and 0.3 g/dL (95%-CI: 0.12 to 0.48; 1 study), respectively. Micronutrient fortification also led to a reduced risk of having anemia (risk ratio 0.59 (95%-CI 0.44 to 0.80)). Ferritin concentrations increased with fortified condiments. Functional outcomes were rarely assessed and showed mixed results. The use of micronutrient fortified condiments can be a strategy to reduce anemia in children and adults due to micronutrient deficiencies. The effect of fortified noodles seems to be smaller
Impacts and challenges of Community Health Planning Services (CHPS) facilities in rural Ghana
Interplay between foetal haemoglobin, micronutrients and oxidative stress biomarkers in sickle cell anaemia children
Foetal haemoglobin (HbF) has been speculated to have an impact on the quantity of micronutrients and the latter also have a role to play in oxidative stress (OS) in sickle cell anaemia (SCA). No previous study in Ghana has examined the interplay of these factors together among SCA children. This study compared the levels of OS biomarkers (8-hydroxy-deoxyguanosine [8-OHdG] total antioxidant capacity [TAC]) and micronutrients (zinc and copper), and their relationship with HbF in SCA and sickle cell negative, apparently healthy children. This case-control study recruited 58 SCA (out-patients [n = 42] and in-patients [n = 16]) children aged 1–14 years as cases and 62 sickle cell negative children as controls from the Sickle Cell Unit at the Eastern Regional Hospital, Ghana. The micronutrients were measured using the atomic absorption spectrophotometer (AAS) whereas OS biomarkers and HbF were assayed using enzyme-linked immunosorbent assay (ELISA). SCA out-patients had a significantly higher level of HbF compared to HbA patients (p = 0.035). SCA in-patients had significantly increased levels of zinc, but a reduced 8-OHdG than SCA out-patients compared to control group (p \u3c 0.05). HbF correlated significantly (r = 0.318, p \u3c 0.038) with zinc in SCA out-patients. Micronutrients are essential in maintaining the redox status in SCA out-patients and HbF can influence some micronutrients
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