HyperLoom: A platform for defining and executing scientific pipelines in distributed environments

Real-world scientific applications often encompass end-to-end data processing pipelines composed of a large number of interconnected computational tasks of various granularity. We introduce HyperLoom, an open source platform for defining and executing such pipelines in distributed environments and providing a Python interface for defining tasks. HyperLoom is a self-contained system that does not use an external scheduler for the actual execution of the task. We have successfully employed HyperLoom for executing chemogenomics pipelines used in pharmaceutic industry for novel drug discovery.6

Effectiveness of financial incentives to improve adherence to maintenance treatment with antipsychotics: cluster randomised controlled trial

Objective: To test whether offering financial incentives to patients with psychotic disorders is effective in improving adherence to maintenance treatment with antipsychotics. Design: Cluster randomised controlled trial. Setting: Community mental health teams in secondary psychiatric care in the United Kingdom. Participants: Patients with a diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder, who were prescribed long acting antipsychotic (depot) injections but had received 75% or less of the prescribed injections. We randomly allocated 73 teams with a total of 141 patients. Primary outcome data were available for 35 intervention teams with 75 patients (96% of randomised) and for 31 control teams with 56 patients (89% of randomised). Interventions: Participants in the intervention group were offered £15 (€17; $22) for each depot injection over a 12 month period. Participants in the control condition received treatment as usual. Main outcome measure: The primary outcome was the percentage of prescribed depot injections given during the 12 month intervention period. Results 73 teams with 141 consenting patients were randomised, and outcomes were assessed for 131 patients (93%).⇓ Average baseline adherence was 69% in the intervention group and 67% in the control group. During the 12 month trial period adherence was 85% in the intervention group and 71% in the control group. The adjusted effect estimate was 11.5% (95% confidence interval 3.9% to 19.0%, P=0.003). A secondary outcome was an adherence of ≥95%, which was achieved in 28% of the intervention group and 5% of the control group (adjusted odds ratio 8.21, 95% confidence interval 2.00 to 33.67, P=0.003). Although differences in clinician rated clinical improvement between the groups failed to reach statistical significance, patients in the intervention group had more favourable subjective quality of life ratings (β=0.71, 95% confidence interval 0.26 to 1.15, P=0.002). The number of admissions to hospital and adverse events were low in both groups and did not show substantial differences. Conclusion: Offering modest financial incentives to patients with psychotic disorders is an effective method for improving adherence to maintenance treatment with antipsychotics

Prospectus, August 30, 1983

NEW PARK-LAND APARTMENTS FILL EMPTY FIELD SOUTH OF PARKLAND; Survival hints for Parkland; News Digest; President Staerkel welcomes new students to Parkland; September 1983 Parkland College Calendar; Is your class cancelled?; Bookstore supplies more than books; Everyone is welcome to enjoy Fall-In \u2783; StuGo welcomes all; New addition takes care of classroom needs; Choose your movies; Lindstrand awards six films as best summer flics; Chase has bad vacation--produces funny flic; Keaton and Garr star in Mr. Mom ; Greatest Show returns to Assembly Hall; New Doctor Who to be televised; Reviewing summer\u27s top music hits; Skylines; Parkland employees honored; Neal retires; Classified; Guard goes north for summer camp; Police fingerprint children; Beginning Again program for bereaved; Improve bowling skills--join Bowling Club; Woods Words: Stadium to celebrate its 60th yearhttps://spark.parkland.edu/prospectus_1983/1013/thumbnail.jp

Prospectus, December 1, 1983

SKETCHES TELL STORIES; News Digest; Boisso - striving to improve; PC Happenings: Cabin Fever, Holiday play; Students keep candy on hand; Club Notes; Crime and drug abuse never to lower to 1950-69 level; Treat hypothermia; Artists will be able to display art on video; Question: What did you think of \u27The Day After\u27?; Fellow students sharing their talents during \u27Celebrate the Arts Week\u27; Classified; PC grad to Texas; \u27Rear Window\u27 first of Hitchcock re-releases; Rock and Roll with \u27the Kid\u27; King trips with \u27Pet\u27; Free theater offered to students; Police attracts fans from all over; Parkland edges Spoon River; IOC shoots past Cobras; Composite Athletic Schedule; Fast Freddy Contesthttps://spark.parkland.edu/prospectus_1983/1002/thumbnail.jp

Prospectus, February 27, 1985

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Prospectus, May 2, 1984

SUPPORT YOUR COLLEGE! VOTE FOR STUDENT GOVERNMENT OFFICERS; News Digest; Students protest CIA campus recruitment; PC Happenings; Humanities Awards Program Summer Research; Student Government candidate platforms; Fearing suits, many colleges move to control students closely; Creative Corner...Especially for you!!; Energy from the Garden; Elf; Bums; Rites of Passage; Angie; To Those Who Have Loved and Lost...; Nuclear Weapons Freeze; Finney\u27s Famous Fanwich, on Rye; Settlement on the Sangamon; Freedom summer campaign seeks 5,000 students; Campaign for a Humane Center; Non-Event kick-off; Did you know...; Classifieds; Parkland\u27s Fine Art students\u27 work exhibited in Art Gallery; Philosophy discussion group--know yourself and your world; Top AHT students receive awards; March of Dimes plans events; Two artists exhibit work; Campus springtime; \u27The Hollywood Hall of Shame\u27 -- behind the scenes dirt; \u27Android\u27 high quality with low budget; WILL airs high drama; Sports Digest; Midwest Open successful; Parkland\u27s women\u27s basketball team finishes third offensively; Scholarships should help Parkland\u27s athletics; Cobras split with Vincennes with two from Olneyhttps://spark.parkland.edu/prospectus_1984/1022/thumbnail.jp