Comparing Relationship between Quality of Earning and Stock Return of Companies Listed in Tehran Stock Exchange

In this research, role of accruals in description of earning quality of the companies listed in Tehran Stock Exchange has been studied and relationship between quality of earning, through accruals and its constituents, and normal stock return has been studied. Correlation analysis and historical information of the companies used as the research method. The statistical sample includes 109 companies in Tehran Stock Exchangeduring 2009-2013. For data analysis and hypothesis testing, Multiple Linear Regression Model based on panel data has been used with Estimated Generalized Least Square (EGLS) by applyingEviews and Stata softwares.Three hypotheses were developed to determine relationship between earning quality and stock return. Results of the research indicated that there is a direct and significant relationship between accruals and normal stock return in Tehran Stock Exchange. No significant relationship was found between non-discretionary accruals and normal return

N,N′-Dicyclo­hexyl-N′′,N′′-dimethyl­phospho­ric triamide

In the title compound, C14H30N3OP, both cyclo­hexyl groups adopt chair conformations with the NH unit in an equatorial position. The P atom adopts a slightly distorted tetra­hedral environment. In the (CH3)2NP(O) unit, the O—P—N—C torsion angles, showing the orientations of the methyl groups with respect to the phosphoryl group, are −166.6 (3) and 34.6 (4)°. The O atom of the P=O group acts as a double hydrogen-bond acceptor and is involved in two different inter­molecular N—H⋯OP hydrogen bonds, building R 2 2(8) rings that are further linked into chains running parallel to the b axis

Efficiency of the Combined Chemical Precipitation -Reduction Process to Remove Dye and Chromium from Industry Wastewater of Home Appliance

Background: Industrial wastewater is one the most important pollutants of environment. This study aimed to evaluate the efficiency of the combined chemical precipitation-reduction process for removal of dye and chromium from wastewater of home appliance factories. Methods: This experimental study was performed in laboratory scale on wastewater from the dying unit of the home appliance factory. The process used was a combination of the chemical precipitation-reduction process. Combine sampling was done and 214 samples were analyzed. COD, dye, and chromium were measured in samples. MgCl2, Polyaluminium Chloride (PAC), and FeCl3, cationic polymer and bentonite were used for chemical precipitation; and sodium meta bi sulfite was used for chemical reduction. Data were analysed by ANOVA and Tukey tests and by SPSS 16 software. Results: The results show that PAC had the highest color removal efficiency (90.92%). Also, the highest COD removal was related to the combination of magnesium chloride (1.4 mg/l), poly aluminum chloride (0.6 mg/l), and the coagulant aid cationic polymer (0.4 mg/l) with an efficiency of 89.11%. Moreover, total efficiency of the combined chemical precipitation and reduction process in chromium removal was 94%. Conclusion: The chemical precipitation- reduction process as a pre-treatment method has high efficiency in removal of COD, dye and chrome from wastewater of home appliance factories

A review on the application of hairy roots in removing phenolic compounds from aqueous solutions

Background and Objective: The presence of toxic compounds, including phenol, due to industrial development, poses a threat to the environment. Utilizing hairy roots has emerged as a potential method to remove these toxins. This review aims to explore the efficacy of hairy roots in absorbing phenol pollutants and the influencing parameters. Materials and Methods: This study was conducted using a descriptive-review method based on existing literature gathered from databases such as Science Direct, PubMed, and Google Scholar. The focus of the study was on the purification of phenol using hairy roots. Keywords such as Phytoremediation, Hairy root, Phenol, and Transgenic roots were used for data collection. Results: Results show successful phenol removal by hairy roots, potentially attributed to abundant production of peroxidase enzymes. Various factors, such as hydrogen peroxide (H2O2), incubation time, pH, plant species, and pollutant concentration, impact phenol removal efficiency. Notably, plants like Brassica napus, rich in peroxidase enzymes, exhibit high efficiency in removing phenol pollution up to 500 mg/L, with H2O2 and within a pH range of 4-9. Conclusion: In conclusion, hair roots possess significant adsorption capacity for phenol. However, phenol concentration, contact time, pH, and temperature influence their performance. Therefore, further research is required to explore optimal conditions for phenol removal

Zingiber officinale Roscoe reduces chest pain on patients undergoing coronary angioplasty: a clinical trial

Introduction: Evidence from animal studies suggests that Zingiber officinale (ginger) may help prevent ischemia–reperfusion injury (IRI) in heart. The aim of the present study was to investigate the effect of ginger on inducing preconditioning on patients undergoing angioplasty. Methods: Thirty-four patients, referred for elective angioplasty, were randomly divided into the control (17 patients) and ginger groups (17 patients). Subjects in the experimental group were provided 250 mg ginger powder in Zintoma capsules per day for 10 days, whereas those in the control group received placebo. The patients underwent percutaneous transluminal coronary angioplasty (PTCA) (One 45-second balloon inflation and 2 minutes reperfusion). Chest pain scores were assessed immediately after angioplasty and cardiac injury biomarkers were assessed 12 hours later. Results: The average pain score during the balloon inflation in the ginger group was significantly lower than the control group (2.1±1 versus 3.8±1.5, P = 0.04). Troponin I was elevated in both groups after angioplasty, but there was not any significant difference between groups in this regard (P = 0.12 and 0.10, respectively). Conclusion: The use of ginger reduces chest pain during coronary angioplasty but its effect on the release of biochemical markers of myocardial damage is obscure

p-Tolyl bis­(p-tolyl­amido)phosphate

In the title compound, C21H23N2O2P, the P atom exhibits tetra­hedral coordination; the P—N bond lengths are relatively short [1.6297 (13) and 1.6424 (13) Å]. In the crystal, adjacent mol­ecules are linked by N—H⋯O hydrogen bonds into a zigzag chain running along the c axis

Shigella dysentery stxA mutant (R170L-A231D-G234E) gene design and optimization of recombinant protein expression and purification

زمینه و هدف: شیگلا دیسانتری یکی از مهمترین باکتری های بیماریزا‌ی روده‌ای انسان است. شیگاتوکسین (سم این باکتری) با ورود به سلول های اپیتلیال باعث مهار سنتز پروتئین و مرگ سلولی می شود. علیرغم مطالعات فراوان جهت تولید واکسن علیه آن، هنوز ضرورت تداوم مطالعه در حصول به پروتئین نوترکیب شیگاتوکسین نوع A (stxA) وجود دارد. این مطالعه با هدف بررسی و تعیین جایگاه های مناسب جهش و طراحی ژن سینتتیک زیر واحد stxA و سپس بیان و بهینه سازی آن و در نهایت بررسی روش تخلیص آن جهت مطالعات بعدی ایمنی زایی انجام شد. روش بررسی: در این مطالعه توصیفی-آزمایشگاهی پس از طراحی و تهیه ژن صناعی pET28a/stxA موتانت (G234E– R170L -A231D)، واکنش PCR جهت کنترل صحت حضور این ژن انجام گردید. پس از انتقال این وکتور به سلول میزبان Bl21 DE3، بیان، بهینه سازی و نهایتاً تخلیص پروتئین حاصل بررسی گردید. یافته ها: نتیجه مطالعات اولیه منجر به طراحی ژن stxA موتانت گردید. نتایج واکنش PCR با استفاده از پلاسمید سنتتیک نشان از صحت ژن مورد مطالعه داشت. پس از بیان این ژن در سلول میزبان Bl21 DE3، بهینه سازی آن نیز بررسی گردید. در نتیجه تولید مقادیر زیادی از این پروتئین به شکل اجسام توده ای نشان داده شد. تخلیص انکلوژن بادی و سپس محلول سازی پروتئین های مربوطه با استفاده از روش های تلفیقی صورت گرفت. نتیجه گیری: با توجه به مکانیسم اثر شیگاتوکسین و طراحی جهش های انتخابی با آرایش جدید در این ژن، پیش بینی می شود که این پروتئین بیانی، دارای اثر سمیت کمتری نسبت به سایر موتانت های قبلی داشته باشد، در نتیجه می تواند به عنوان کاندید واکسن برتر مطرح گردد

Decay resistance of wood impregnated with monoethanolamine and sodium bisulfite pulping black liquors

The efficacy of monoethanolamine and sodium bisulfite pulping black liquors at three concentrations of 1; 1,5 and 2% on the preservation of poplar wood from white rot (Trametes versicolor) was investigated. The wood specimens were impregnated with the black liquors using a full-cell method. The black liquors enhanced the decay resistance without any reduction in mechanical strength, and a remarkable increase was observed at higher concentrations and weight gain percentage. The performance of monoethanolamine black liquor was more pronounced, probably due to lower kappa number and higher pH. The durability class of specimens impregnated with 2% monoethanolamine and sodium bisulfite black liquors improved from 5 (not durable) to 1 (very durable), and from 5 to 3 (moderately durable), respectively. Chemical analysis showed that the presence of additional lignin in wood alters the white rot. Results of anatomical studies showed that the fibers of the control and impregnated wood specimens were collapsed after 16 weeks of incubation. Leaching tests confirmed that the fixation of black liquors in wood should be examined for further studies.   PDF XM

A phase III, randomized, two-armed, double-blind, parallel, active controlled, and non-inferiority clinical trial to compare efficacy and safety of biosimilar adalimumab (CinnoRA (R)) to the reference product (Humira (R)) in patients with active rheumatoid arthritis

Background: This study aimed to compare efficacy and safety of test-adalimumab (CinnoRA (R), CinnaGen, Iran) to the innovator product (Humira (R), AbbVie, USA) in adult patients with active rheumatoid arthritis (RA). Methods: In this randomized, double-blind, active-controlled, non-inferiority trial, a total of 136 patients with active RA were randomized to receive 40 mg subcutaneous injections of either CinnoRA (R) or Humira (R) every other week, while receiving methotrexate (15 mg/week), folic acid (1 mg/day), and prednisolone (7.5 mg/day) over a period of 24 weeks. Physical examinations, vital sign evaluations, and laboratory tests were conducted in patients at baseline and at 12-week and 24-week visits. The primary endpoint in this study was the proportion of patients achieving moderate and good disease activity score in 28 joints-erythrocyte sedimentation rate (DAS28-ESR)-based European League Against Rheumatism (EULAR) response. The secondary endpoints were the proportion of patients achieving American College of Rheumatology (ACR) criteria for 20% (ACR20), 50% (ACR50), and 70% (ACR70) responses along with the disability index of health assessment questionnaire (HAQ), and safety. Results: Patients who were randomized to CinnoRA (R) or Humira (R) arms had comparable demographic information, laboratory results, and disease characteristics at baseline. The proportion of patients achieving good and moderate EULAR responses in the CinnoRA (R) group was non-inferior to the Humira (R) group at 12 and 24 weeks based on both intention-to-treat (ITT) and per-protocol (PP) populations (all p values >0.05). No significant difference was noted in the proportion of patients attaining ACR20, ACR50, and ACR70 responses in the CinnoRA (R) and Humira (R) groups (all p values >0.05). Further, the difference in HAQ scores and safety outcome measures between treatment arms was not statistically significant. Conclusion: CinnoRA (R) was shown to be non-inferior to Humira (R) in terms of efficacy at week 24 with a comparable safety profile to the reference product

The Efficiency of Peroxone Process in Packed Reactor for Removal of Anionic Surfactants and COD from Carwash Wastewater

Background: Carwash is an industry that consumes large amounts of water and its wastewater contains a variety of pollutants. The aim of this study was to investigate the efficiency of the Peroxone process as a method for wastewater treatment of carwashes. Methods: This study was conducted at laboratory scale. A total of 54 samples were collected from a carwash in Yazd city and COD and anionic surfactants removal percentages were respectively determined by using the standard vial and anionic surfactants method and Methylene Blue Active Substances (MBAS). The process was conducted with an ozone dose of 0.7 mg per min, H2O2 concentrations of 10, 20 and 40 mmol per liter, reaction times of 30, 60 and 90 min and pH of 7, 9 and 11 in a cylindrical reactor respectively. Data were analyzed using ANOVA and through SPSS 18. Results: The removal efficiencies of COD and anionic surfactants increased with increasing pH and reaction time; so that, at pH =11 and after a reaction time of 90 minutes for an ozone dose of 0.7 mg/min and H2O2 concentration of 40 mmol/l, removal efficiency of COD and anionic surfactants were respectively 74.77% and 74.27%. Conclusion: The peroxone process has a good ability for removal of COD and anionic surfactants. Similar studies confirm the findings of this study. Meanwhile, pretreatment methods are recommended for further evaluation of this process