1,390 research outputs found
African Politics in the Digital Age: A Study of Political Party-Social Media Campaign Strategies in Ghana
Digital media is transforming politics. It has made it imperative for political stakeholders to come up with new strategies that respond to challenges triggered by the new digital communication platforms. Equally, the technological developments have affected communication processes and strategies in transitional political contexts, with varying impacts on democratic governance, political participation and forms of deliberation for citizens. However, the actual impact of social media on political processes remains debatable. Many issues emerge including not only how communications technologies revitalise campaign techniques but also how they influence actors, organisations and reorient political campaigning environments. In Africa, it is important to ask in specific contexts how the new technologies are reconfiguring the relationship between the rulers and the ruled, between politicians and the electorate. In particular, how has digital media facilitated new forms of political communications to individuals and groups? Has it gone beyond geography, class, gender, language or race? What has been the specific impact on campaign strategies, and their process and impact on electoral politics in countries such as Ghana, an emerging democracy? Through a case study, this research has explored the changing dynamics of election campaigning in Ghana in the context of social media. By examining the influence of Facebook, Twitter Instagram and other Social Network Sites (SNSs) for political campaigning, the research produces an original analysis of digital political communication, organization and mobilization, among others, as they are deployed by the main political parties, namely, the National Democratic Congress (NDC) and the New Patriotic Party (NPP), with a focus on the 2012 and 2016 elections. The study has adopted a qualitative research methodology, based on in-depth interviews (formal and informal), focus group discussions, as well as informal observation techniques, which were applied to gather original evidence. The main findings are that social media is implicated in political campaigns in multiple ways, with its ability to change, and are dependent on the availability of resources and policy frameworks that regulate and streamline their usages. The study shows how the campaign process is also implicated by political organizations, actors and voters, rather than just by the technologies. The research has uncovered the role of offline/digital ‘serial callers’, those quasi political communicators hired by political parties to influence political campaigning. Challenges and limitations notwithstanding, the research provides an invaluable insight into the relationship between the use of social media for political communication and its ramifications for democratization in Ghana. It contributes original insights on the shifts and impact of political communication within the African context
Governance of new product development and perceptions of responsible innovation in the financial sector: insights from an ethnographic case study
types: ArticleThis is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Responsible Innovation on 24 Feb 2014, available online:
http://wwww.tandfonline.com/10.1080/23299460.2014.882552We describe an ethnographic study within a global asset management company aimed at understanding the process and governance of new product development and perceptions of responsible innovation. We observed innovation to be incremental, with a clearly - structured stage gating model of governance involving numerous internal and external actors that was framed by regulation and co-ordinated by a small product development team. Responsible innovation was framed largely in terms of considering client needs when innovating and the understanding of operational, legal, regulatory and reputational risks. Staff perceived the company as having an inherently cautious culture, where the probability of bringing something destructive to market was perceived as being low. We conclude that the observed stage gating architecture offers considerable scope as a mechanism for systematic embedding of more broadly framed, emerging concepts of responsible innovation
Impact of Urban Effluents on the Macroinvertebrates of a Creek in Accra, Ghana
The impact of effluents on the macroinvertebrate communities of an urban creek in Accra was studied. Five study stations were selected along the reaches of the creek. Water and benthic samples were collected and analyzed between September 2005 and February 2006. The study showed that the effluent discharges caused a significant increase in BOD, COD and NH3 at the stations that received the effluents. The high levels of total and faecal coliforms at the midstream sections of the creek (626.0 x 104 cfu/100 ml and 75.30 x 104 cfu/100 ml, respectively) indicated increased pollution levels compared to the reference stations (446.0 x 103 cfu/100 ml and 133.0 x 103 cfu/100 ml). The Nima Creek showed characteristics of a disturbed urban creek. A total of 19 macroinvertebrate taxa, comprising a total of 11,613 individuals, were collected. Estimated Shannon-Weiner Diversity Index (H´) was low at the midstream section of the creek, H’= 1.14, where the effluents were concentrated than at the upstream H’=1.44 or downstream H’= 1.38 sections of the creek. Chironomini and Physa were the most abundant taxa within the creek, dominated by the genus Chironomus, which is known to be tolerant to pollution, which confirmed the polluted state of the creek. Rigorous and regular assessment and monitoring of effluents from waste treatment plants and other sources that discharge into the creek, with the aim of complying with the Environmental Protection Agency (EPA) guidelines are some of the mitigative measures suggested to protect life in the creek
Molecular characterization of methicillin-resistant Staphylococcus aureus isolates from a hospital in Ghana
Background: Methicillin-resistant Staphylococcus aureus (MRSA) are a major cause of hospital- and community-acquired infection. They can colonize humans and cause a wide range of infections including pneumonia, endocarditis and bacteraemia. We investigated the molecular mechanism of resistance and virulence of MRSA isolates from a teaching hospital in Ghana.Methodology: A total of 91 S. aureus isolates constituted the initial bacterial sample. Identification of S. aureus was confirmed by the VITEK 2 system. The cefoxitin screen test was used to detect MRSA and antibiotic susceptibility was determined using the VITEK 2 system. The resistance (mecA, blaZ, aac-aph, ermC, and tetK) and virulence (lukS/F-PV, hla, hld and eta) genes were amplified by polymerase chain reaction (PCR) and positive samples subjected to DNA sequencing. Pulsed field gel electrophoresis (PFGE) was used to ascertain the relatedness of the isolates.Results: Fifty-eight of 91 (63.7%) isolates were putatively methicillin resistant by the phenotypic cefoxitin screen test and oxacillin MICs. However, 43 (47%) of the isolates were genotypically confirmed as MRSA based on PCR detection of the mecA gene. Furthermore, 37.9% of isolates displayed resistance to tetracycline, 19% to trimethoprim-sulphamethoxazole, 15.5% to clindamycin, 12.1% to gentamicin, 13.8% to ciprofloxacin and erythromycin, 6.9% to moxifloxacin and 7.0% to rifampicin. None of the isolates was positive for inducible clindamycin resistance. The prevalence of resistance (mecA, blaZ, aac(6’)-aph(2’’), tetK, and ermC) and virulence (hla and lukS/F-PV) genes respectively were 74%, 33%, 22%, 19%, 3%, 5% and 3%, with isolates organized in two highly related clades.Conclusion: Results indicate a fairly high occurrence of MRSA, which can complicate the effective therapy of S. aureus infections, necessitating surveillance and stringent infection control programmes to forestall its spread.Keywords: MRSA, mecA, blaZ, hla, lukS/F-P
Groundwater Vulnerability Assessment using Drastic Index and GIS in Kumasi Metropolitan Assembly, Ghana
The assessment of groundwater vulnerability to contamination has become an important element for landuse planning and groundwater resource management. This study aims at estimating groundwater vulnerability using an integration of Geographic Information System (GIS) and DRASTIC method in the Kumasi Metropolitan Assembly (KMA). The groundwater vulnerability map was prepared using index and overlay analysis with the aid of Arc GIS 10. The DRASTIC Index (DI) computed ranged between 70 and 164 as the lowest and highest contamination potential respectively. The eastern and western flanks and north-west tip of KMA are underlain by the granites which bear water due to the combined effect of weathering and fracturing and are dominated by "Very High", "High" and "Moderate" vulnerability based on the vulnerability index computed. The "Low" and "Very Low" vulnerability are located at the northern, central and southern parts of KMA which are underlain by phyllites. These suggest that boreholes located in the Birimian metasedimentary units which comprise mainly phyllites would be less likely to be vulnerable to contamination than those located in the intrusive rocks dominated by the granites. Keywords: Groundwater Vulnerability, Soil Media, Hydraulic Conductivity, Overlay Analysi
Adolescent Problem Gambling in Rural Ghana: Prevalence and Gender Differentiation
Abstract
Problem gambling among young people is now a public health challenge in sub-Saharan Africa. However, the behaviour remains understudied, particularly, among rural-dwelling young people in countries within the subregion. We aimed to estimate the 12 months prevalence of problem gambling and to describe the overall and gender differences and commonalities in personal factors and social adversities associated with problem gambling among adolescents in rural Ghana. We conducted a cross-sectional survey involving a random sample of 1101 in-school adolescents aged 10–19 years in a rural district in Eastern Ghana; we used the DSM-IV-Multiple Response-Juvenile (DSM-IV-MR-J) questionnaire to assess problem gambling during the previous 12 months. Personal lifestyle and psychosocial variables were assessed using adopted items from the 2012 WHO–Global School-based Student Health Survey. Overall, three in 10 adolescents (3 in 10 females; 4 in 10 males) in rural Ghana reported problem gambling in the previous 12 months. Female adolescents who experienced problem gambling were more likely to report family-related social adversities, while adolescent male problem gambling was associated with school-related factors and interpersonal factors outside the family context. Regardless of gender, sexual abuse victimisation was associated with three times increase in the odds of experiencing problem gambling. Relative to the prevalence of gambling among adolescents in urban contexts in other countries within sub-Saharan Africa, the estimates of problem gambling among in-school rural adolescents in Ghana are higher. Although further studies are needed to understand the nuances of the behaviour, the evidence of this study underscores the need for general and targeted health promotion, intervention and prevention efforts to mitigate the family, school, and interpersonal social adversities associated with adolescent problem gambling in rural Ghana.</jats:p
Observations from a prospective small cohort study suggest that CGRP genes contribute to acute posttraumatic headache burden after concussion
Introduction: Post-traumatic headache (PTH) is commonly reported after concussion. Calcitonin gene-related peptide (CGRP) is implicated in the pathogenesis of migraine. We explored how single nucleotide polymorphisms (SNPs) from CGRP-alpha (CALCA) and the receptor activity modifying protein-1 (RAMP1) related to headache burden during the first week after concussion.
Methods: A prospective study was performed in 34 collegiate athletes who sustained a concussion. Participants completed the symptom evaluation checklist from the SCAT3 within 48 h of injury (V1), and again 4 (V2) and 7 (V3) days after injury. For each visit, the self-reported score (0–6) for headache, pressure in head, blurred vision, and sensitivity to light/noise were reported and summed to calculate the headache burden. A saliva sample was obtained and genotyped for CALCA (rs3781719) and RAMP1 (rs10185142). RAMP1 (TT, TC, CC) and CALCA (AA, AG, GG) were dichotomized (A+, A- and T+, T-, respectively), and concatenated (T+A+, T+A-, T-A+, T-A-) for analyses.
Results: Headache Burden at Visit 1 was greatest in T+A+ compared to T-A+, and trended toward a significant difference with T+A-. Repeated-measures ANOVA revealed the presence of significant visit main effects (p < 0.001, η2 = 0.404), but the group (p = 0.055) and interaction effects only trended (p = 0.094). Pearson's χ2-tests revealed that 88% of those with return-to play (RTP) exclusions ≥15 days had PTH with multi-sensory symptoms (PTH+SENS) as compared to 35% in those with RTP < 14 day.
Conclusion: Knowledge of RAMP1 and CALCA genotypes appear to improve an understanding the presenting features and magnitude of headache burden after concussion injury
Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein
The epizootic prion disease of cattle, bovine spongiform encephalopathy (BSE), causes variant Creutzfeldt-Jakob disease (vCJD) in humans following dietary exposure. While it is assumed that all cases of vCJD attributed to a dietary aetiology are related to cattle BSE, sheep and goats are susceptible to experimental oral challenge with cattle BSE prions and farmed animals in the UK were undoubtedly exposed to BSE-contaminated meat and bone meal during the late 1980s and early 1990s. Although no natural field cases of sheep BSE have been identified, it cannot be excluded that some BSE-infected sheep might have entered the European human food chain. Evaluation of the zoonotic potential of sheep BSE prions has been addressed by examining the transmission properties of experimental brain isolates in transgenic mice that express human prion protein, however to-date there have been relatively few studies. Here we report that serial passage of experimental sheep BSE prions in transgenic mice expressing human prion protein with methionine at residue 129 produces the vCJD phenotype that mirrors that seen when the same mice are challenged with vCJD prions from patient brain. These findings are congruent with those reported previously by another laboratory, and thereby strongly reinforce the view that sheep BSE prions could have acted as a causal agent of vCJD within Europe
Prevalence of high blood pressure, overweight, and obesity in Ghanaian school children
Background: Obesity is excessive fat accumulation in adipose tissue to the extent that health is impaired. As the body weight increases, the frequency of blood pressure shifts to higher levels. This combination is associated with a greater risk of disability, reduce d quality of life and premature death in early adulthood.Objective: This study aimed to determine the prevalence of overweight, obesity and associated hypertension in school children.Methods: School children aged 5 to 14 years from six schools in Greater Accra, Ghana were randomly recruited into the study. Weight, height and blood pressure were measured. Body mass index was generated and plotted using the WHO Anthroplus software. The association between BMI percentile and blood pressure was also analysed.Results: Six hundred school children were recruited for the study. Of these 59.7% (n = 358 were females and 40.3% (n = 242 were males. The prevalence of overweight and obesity were 11.16% and 11.01% respectively. Overweight (12.8% vs 8.7%) and obesity (11.7% vs . 9.9%) were relatively common among females as compared to males ( p 0.083). Overall, 8.5% (n = 51 of children out of the 600 had elevated blood pressure . Elevated blood pressure was significantly prevalent among obese children 18.2% (n = 12), followed by overweight 13.4% (n = 9 ) and the normal weight of 6.4% (n= for school children ( p 0.002).Conclusion: Hypertension was found among the school children studied and was significantly associated with overweight and obesity. This calls for the promotion of school health education and physical activities to curb hypertension in this population
Attention Bias Toward Threat is Associated with Exaggerated Fear Expression and Impaired Extinction in PTSD
Background: Post-traumatic stress disorder (PTSD) develops in a minority of traumatized individuals. Attention biases to threat and abnormalities in fear learning and extinction are processes likely to play a critical role in the creation and/or maintenance of PTSD symptomatology. However, the relationship between these processes has not been established, particularly in highly traumatized populations; understanding their interaction can help inform neural network models and treatments for PTSD.
Method: Attention biases were measured using a dot probe task modified for use with our population; task stimuli included photographs of angry facial expressions, which are emotionally salient threat signals. A fear-potentiated startle paradigm was employed to measure atypical physiological response during acquisition and extinction phases of fear learning. These measures were administered to a sample of 64 minority (largely African American), highly traumatized individuals with and without PTSD.
Results: Participants with PTSD demonstrated attention biases toward threat ; this attentional style was associated with exaggerated startle response during fear learning and early and middle phases of extinction, even after accounting for the effects of trauma exposure.
Conclusions: Our findings indicate that an attentional bias toward threat is associated with abnormalities in ‘fear load’ in PTSD, providing seminal evidence for an interaction between these two processes. Future research combining these behavioral and psychophysiological techniques with neuroimaging will be useful toward addressing how one process may modulate the other and understanding whether these phenomena are manifestations of dysfunction within a shared neural network. Ultimately, this may serve to inform PTSD treatments specifically designed to correct these atypical processes
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