Prevalence of Non Alcoholic Fatty Liver Disease in patients with Parkinson Disease

INTRODUCTION[|]Non alcoholic fatty liver disease (NAFLD) has presented as the most common cause of chronic liver disease in the Western world. Parkinson disease (PD) is the second most common non-demyelinizan neurologic disase and its incidence is steadily increasing in the world. Our study aims to analyze the prevalence of ultrasonography-proven NAFLD among the PD patients. [¤]METHODS[|]A retrospective chart review was performed to identify PD patients who had at least two visits in the Liver Clinic from January 2017 to May 2018. Thus, 124 consecutive patients (the mean age 74,2+-11,9years; 65 female) with PD was longitudinally screened for NAFLD which were diagnosed according to ultrasonographic criteria. Control subjects (65 subjects, mean age was 68+-3.4 years; 35 female) were selected from age-matched eldely subjects. Demographic and laboratory data, concurrent statin use and results of hepatobiliary ultrasonography were collected. Patients with history of chronic liver disase, liver transplant, past alcohol use or not enough data to stage NAFLD were excluded. Data analyzed using Pearson's chi-squared test with the Stata software.[¤]RESULTS[|]Nonalcoholic fatty liver disease prevalence was significantly lower in the PD group than in the age -matched control group (21% vs. 36%, P<0.05). In multiple logistic regression analyses using baseline factors, statin use (P=0.04) and elevated Hb A 1 C (P<0.001), baseline fasting glucose below than 100 mg/dL (P=0.03), and elevated ALT levels (P<0.001) were independently associated with NAFLD.[¤]DISCUSSION AND CONCLUSION[|]While additional studies in large populations are needed to investigate the correlation between PD and NAFLD, further exploration of PD -related metabolic liver disease clinically appears warranted.[¤

SCREENING FOR HEPATITIS B AND C SEROPREVALENCE AND PREVALENCE OF HIV INFECTION AMONG AFGHAN REFUGEES NEWLY ARRIVED IN COASTAL REGION TURKEY IN 2018: A SYSTEMATIC SINGLE-CENTRE ANALYSIS

Introduction: Previous studies showed that refugee status have been associated with various deteriorated effects on human health including higher prevalence of hepatitis B, C and HIV infections. In this study we aim to bridge the gap between Afghan immigrants and naive Turkish population by identifying HBV, HCV and HIV profiles. In addition, a large number of laboratory parameters was collected for all participants, including hematologic and biochemical test results. Materials and Methods: We performed a retrospective review of laboratory records at a tertiary center in Northern Turkey from January 1, 2018, to April 15, 2018. Our population based study comprising hospital data of 403 Afghan refugees and 400 naive Turkish citizens. Results: Afghan refugees had higher anti-HIV seropositivity than Turkish citizens.(p<0.05).There were no difference between the two groups according to HbsAg and anti-HCV seropositivity. Also Afghan refugees had statistically lower ALT levels, higher hemoglobin levels and higher mean TSH level (p<0.05). Mean T4 level did not show significant difference between the two groups. Conclusion: We need further investigations to find out the risk of infections that originated from immigration

Very preterm birth is a risk factor for increased systolic blood pressure at a young adult age

Children born very prematurely who show intrauterine growth retardation (IUGR) are suggested to be at risk of developing high blood pressure as adults. Renal function may already be impaired by young adult age. To study whether very preterm birth affects blood pressure in young adults, we measured 24-h ambulatory blood pressure (Spacelabs™ 90207 device) and renin concentration in 50 very premature individuals (<32 weeks of gestation), either small (SGA) or appropriate (AGA) for gestational age (21 SGA, 29 AGA), and 30 full-term controls who all were aged 20 years at time of measurement. The mean (standard deviation) daytime systolic blood pressure in SGA and AGA prematurely born individuals, respectively, was 122.7 (8.7) and 123.1 (8.5) mmHg. These values were, respectively, 3.6 mmHg [95% confidence interval (CI) −0.9 to 8.0] and 4.2 mmHg (95% CI 0.4−8.0) higher than in controls [119.6 (7.6)]. Daytime diastolic blood pressure and nighttime blood pressure did not differ between groups. We conclude that individuals born very preterm have higher daytime systolic blood pressure and higher risk of hypertension at a young adult age

Níveis e preditores de ansiedade e depressão em gestantes turcas durante a pandemia de Covid-19

PubMed ID 35213907WOS:000761023500003Objective  In addition to being a medical phenomenon, pandemics affect the individual and society on several levels and lead to disruptions. In the pandemic process, different groups in the population, including pregnant women as a defenseless group, are subjected to psychological threat. The present study aimed to determine the levels of anxiety and depression and related factors in pregnant women during the the coronavirus disease 2019 (Covid-19) pandemic. Methods  The present cross-sectional study was conducted with 269 pregnant women through face-to-face interviews held in Istanbul, Turkey. Regarding the data collection tools, the Cronbach α reliability coefficient was of 0.90 for the Beck Anxiety Inventory, and of 0.85 for the Beck Depression Inventory. Results  Among the participating pregnant women, 30.5% had mild, 17.5% had moderate, and 5.9% had severe anxiety symptoms, whereas 35.3% had mild, 16.7% had moderate, and 2.2% had severe depression symptoms. We found that those who were concerned about their health had 5.36 times (p = 0.04) more risk of developing anxiety, and 4.82 times (p = 0.01) more risk of developing depression than those who were not concerned. Those who had a history of psychiatric disease had 3.92 times (p = 0.02) more risk of developing anxiety than those without it. Conclusion  We determined that about half of the pregnant women included in the study had some degree of anxiety and depression during the COVID-19 pandemic. The risk factors for anxiety and depression among the pregnant women were determined as smoking, concerns about health and getting infected with the coronavirus, history of psychiatric disease, and undergoing regular antenatal care