2,560 research outputs found
Information homeostasis as a fundamental principle governing the cell division and death
To express genetic information with minimal error is one of the key functions of a cell. Here we propose an information theory based phenomenological model for the expression of genetic information. Based on the model we propose, the concept of "information homeostasis" ensures that genetic information is expressed with minimal error. We suggest that together with energy homeostasis, information homeostasis is a fundamental working principle of a biological cell. This model proposes a novel explanation of why a cell divides and why it stops to divide and thus provides novel insight into oncogenesis and various neuro-degenerative diseases. Moreover, the model suggests a theoretical framework to understand cell division and death, beyond specific biochemical pathways
Freedom of Religion and Belief in India and Australia: An Introductory Comparative Assessment of Two Federal Constitutional Democracies
This article considers the freedom of religion and belief (āfree exerciseā) in two secular federal constitutional democracies: India and Australia. Both constitutional systems emerged from the former British Empire and both continue in membership of the Commonwealth of Nations, which succeeded it. However, the similarities end there, for while both separate church and state, and protect free exercise, they do so in very different ways. On the one hand, the Indian Constitution contains express provisions which comprehensively deal with free exercise. On the other hand, while one finds what might appear a protection for free exercise in the Australian Constitution, that protection is far from comprehensive. Instead, unlike its Indian counterpart, the Australian federal democracy depends upon a piecemeal collection of Constitutional, legislative, and common law provisions which, when taken together, seem to achieve plenary protection for free exercise. Still, while India protects free exercise within a comprehensive constitutional framework, and while Australia does so in a disjointed and fragmentary way, both arrive at the same place: a constitutionalism characterized by secularism/separation of church and state combined with a corresponding comprehensive protection for free exercise
Collisions of Jets of Particles from Active Galactic Nuclei with Neutralino Dark Matter
We examine the possibility that energetic Standard Model particles contained
in the jets produced by active galactic nuclei (AGN) may scatter off of the
dark matter halo which is expected to surround the AGN. In particular, if there
are nearby states in the dark sector which can appear resonantly in the
scattering, the cross section can be enhanced and a distinctive edge feature in
the energy spectrum may appear. We examine bounds on supersymmetric models
which may be obtained from the Fermi Gamma-ray Space Telescope observation of
the nearby AGN Centaurus A.Comment: 20 pages, 9 figures; v2: version published in JCA
Baryon Number as the Fourth Color
We propose an extension of the Standard Model in which baryon number is
promoted to be part of a non-Abelian gauge symmetry at high energies.
Specifically, we consider the gauge group SU(4) x SU(2)_L x U(1)_X, where the
SU(4) unifies baryon number and color. This symmetry is spontaneously broken
down to the Standard Model gauge group at a scale which can be as low as a few
TeV. The SU(4) structure implies that each SM quark comes along with an
uncolored quark partner, the lightest of which is stabilized by the generalized
baryon number symmetry and can play the role of dark matter. We explore
circumstances under which one can realize a model of asymmetric dark matter
whose relic abundance is connected to the observed baryon asymmetry, and
discuss unique signatures that can be searched for at the LHC.Comment: 6 pages, 3 figure
Link Prediction by De-anonymization: How We Won the Kaggle Social Network Challenge
This paper describes the winning entry to the IJCNN 2011 Social Network
Challenge run by Kaggle.com. The goal of the contest was to promote research on
real-world link prediction, and the dataset was a graph obtained by crawling
the popular Flickr social photo sharing website, with user identities scrubbed.
By de-anonymizing much of the competition test set using our own Flickr crawl,
we were able to effectively game the competition. Our attack represents a new
application of de-anonymization to gaming machine learning contests, suggesting
changes in how future competitions should be run.
We introduce a new simulated annealing-based weighted graph matching
algorithm for the seeding step of de-anonymization. We also show how to combine
de-anonymization with link prediction---the latter is required to achieve good
performance on the portion of the test set not de-anonymized---for example by
training the predictor on the de-anonymized portion of the test set, and
combining probabilistic predictions from de-anonymization and link prediction.Comment: 11 pages, 13 figures; submitted to IJCNN'201
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