Information homeostasis as a fundamental principle governing the cell division and death

To express genetic information with minimal error is one of the key functions of a cell. Here we propose an information theory based phenomenological model for the expression of genetic information. Based on the model we propose, the concept of "information homeostasis" ensures that genetic information is expressed with minimal error. We suggest that together with energy homeostasis, information homeostasis is a fundamental working principle of a biological cell. This model proposes a novel explanation of why a cell divides and why it stops to divide and thus provides novel insight into oncogenesis and various neuro-degenerative diseases. Moreover, the model suggests a theoretical framework to understand cell division and death, beyond specific biochemical pathways

Freedom of Religion and Belief in India and Australia: An Introductory Comparative Assessment of Two Federal Constitutional Democracies

This article considers the freedom of religion and belief (“free exercise”) in two secular federal constitutional democracies: India and Australia. Both constitutional systems emerged from the former British Empire and both continue in membership of the Commonwealth of Nations, which succeeded it. However, the similarities end there, for while both separate church and state, and protect free exercise, they do so in very different ways. On the one hand, the Indian Constitution contains express provisions which comprehensively deal with free exercise. On the other hand, while one finds what might appear a protection for free exercise in the Australian Constitution, that protection is far from comprehensive. Instead, unlike its Indian counterpart, the Australian federal democracy depends upon a piecemeal collection of Constitutional, legislative, and common law provisions which, when taken together, seem to achieve plenary protection for free exercise. Still, while India protects free exercise within a comprehensive constitutional framework, and while Australia does so in a disjointed and fragmentary way, both arrive at the same place: a constitutionalism characterized by secularism/separation of church and state combined with a corresponding comprehensive protection for free exercise

Collisions of Jets of Particles from Active Galactic Nuclei with Neutralino Dark Matter

We examine the possibility that energetic Standard Model particles contained in the jets produced by active galactic nuclei (AGN) may scatter off of the dark matter halo which is expected to surround the AGN. In particular, if there are nearby states in the dark sector which can appear resonantly in the scattering, the cross section can be enhanced and a distinctive edge feature in the energy spectrum may appear. We examine bounds on supersymmetric models which may be obtained from the Fermi Gamma-ray Space Telescope observation of the nearby AGN Centaurus A.Comment: 20 pages, 9 figures; v2: version published in JCA

Baryon Number as the Fourth Color

We propose an extension of the Standard Model in which baryon number is promoted to be part of a non-Abelian gauge symmetry at high energies. Specifically, we consider the gauge group SU(4) x SU(2)_L x U(1)_X, where the SU(4) unifies baryon number and color. This symmetry is spontaneously broken down to the Standard Model gauge group at a scale which can be as low as a few TeV. The SU(4) structure implies that each SM quark comes along with an uncolored quark partner, the lightest of which is stabilized by the generalized baryon number symmetry and can play the role of dark matter. We explore circumstances under which one can realize a model of asymmetric dark matter whose relic abundance is connected to the observed baryon asymmetry, and discuss unique signatures that can be searched for at the LHC.Comment: 6 pages, 3 figure

Link Prediction by De-anonymization: How We Won the Kaggle Social Network Challenge

This paper describes the winning entry to the IJCNN 2011 Social Network Challenge run by Kaggle.com. The goal of the contest was to promote research on real-world link prediction, and the dataset was a graph obtained by crawling the popular Flickr social photo sharing website, with user identities scrubbed. By de-anonymizing much of the competition test set using our own Flickr crawl, we were able to effectively game the competition. Our attack represents a new application of de-anonymization to gaming machine learning contests, suggesting changes in how future competitions should be run. We introduce a new simulated annealing-based weighted graph matching algorithm for the seeding step of de-anonymization. We also show how to combine de-anonymization with link prediction---the latter is required to achieve good performance on the portion of the test set not de-anonymized---for example by training the predictor on the de-anonymized portion of the test set, and combining probabilistic predictions from de-anonymization and link prediction.Comment: 11 pages, 13 figures; submitted to IJCNN'201