Lettere inedite di Domenico Cirillo a Giovanni Bianchi (Jano Planco)

Five letters are proposed addressed to Jano Planco, four from Domenico Cirillo and one from John Symonds. Through this correspondence, not only the importance of scientific corre-spondence is highlighted, but also the antiquarian-naturalistic mentality that characterized the century of Enlightenment. This way of thinking, in the kingdom of Naples, was linked above all to the diffusion of the theories of Giannone and Vico in some cultural environments that inherited the strong interest in experimental science.Vengono proposte cinque lettere indirizzate a Jano Planco, quattro di Domenico Cirillo e una di John Symonds. Attraver-so questo carteggio si mette in evidenza non solo l’importanza della corrispondenza scientifica, ma anche la mentalità antiquario-naturalistica che ha caratterizzato il secolo dei Lumi. Tale modo di pensare, nel regno di Napoli, fu legato soprattutto alla diffusione delle teorie di Giannoni e Vico in alcuni am-bienti culturali che ereditarono il forte interesse per la scienza sperimentale

Teatro anatomico dell’Ospedale di San Francesco o delle Prigioni di Napoli

The study of anatomy is a fundamental path for dealing with medical and surgical problems. This aspect was already known to Frederick II of Swabia who issued, even before the institutional and pontifical dispensations and authorizations, including the bull of Sixtus IV, regulations that required anatomical studies. On this path Antonio Nanula founded the Anatomical Theater in the Prisons or San Francesco di Paola Hospital. In this work, not only the salient as-pects of the "life" of this theater are outlined, through little-known documents, but also an attempt is made to trace some aspects of the life of the anatomist.Lo studio dell’anatomia è un percorso fondamentale per affrontare le problematiche mediche e chirurgiche. Questo aspetto già era noto a Federico II di Svevia che emanò, an-cor prima delle dispense e delle autorizzazioni istituzionali e pontificie, tra le quali la bolla di Sisto IV, regolamenti che imponevano gli studi anatomici per i medici. Su questo percorso Antonio Nanula, fondò il teatro anatomico nell’Ospedale delle Prigioni o di San Francesco di Paola. Si delineano, in questo lavoro, non solo gli aspetti salienti della “vita” di questo teatro, attraverso documenti poco conosciuti, ma si cerca anche di tracciare alcuni aspetti della vita dell’anatomista

Role of Laryngopharyngeal Reflux in Eustachian Tube Dysfunction in Adults

We have here studied the relationship between Eustachian tube dysfunction and laryngopharyngeal reflux, evaluating also the results of medical therapy in patients with such problems. Based on clinical, endoscopic and cytological investigations, we found that acid laryngopharyngeal reflux was the basis of audiological symptoms and chronic dysfunction of the Eustachian tube

PHYTOTHERAPEUTIC TREATMENT OF ALLERGIC RHINITIS IN AUTISTIC SUBJECT

In this study the efficacy of a nasal spray based on extract of lemon pulp for treatment of allergic rhinitis in autistic subjects by nasal cytology was evaluated. The extract of lemon pulp was obtained by means of an innovative technology of solid-liquid extraction using Extractor Naviglio or Rapid Solid-Liquid Dynamic Extractor, that can extracts vegetable matrices of each species, by using different types of solvents (organic and/or inorganic liquids). Due to pressure-depressure action, by using water as extractive liquid it is possible to extract both hydrophilic and lipophilic substances contained in vegetables. The efficacy of the lemon based nasal spray has been tested on 20 young patients aged between three and eight years (10 males and 10 females, mean age 5.5 years). The cytology was performed by exfoliative technique, with a sterile swab soaked in sterile saline solution and then crawled on the middle part of the inferior turbinate. The collected sample was stained with the method of May-Giemsa Grumwald to highlight the morphological changes of the nasal epithelium before and after therapy based on nasal spray. Experimental data demonstrated that the antiinflammatory effect of the lemon based nasal spray was a safe medical device as an aid in the reduction of inflammatory cells observed on rinocitogram. The lemon based nasal spray containing extract of lemon pulp can be used in all autistic patients, even in children, given the absence of alcohol

APPROACH UNDER THE FORM OF SEMIQUANTITATIVE CYTOLOGICAL EVALUATION FOR CHRONIC PHARYNGITIS

In this study, we propose a semi-quantitative evaluation form for diagnosis of chronic pharyngitis based on both subjective and objective parameters. The data collection symptom of patients together with the microscopic evaluation of the cytological specimen allows to diagnose with a high degree of certainty the severity of the inflammatory state of the pharynx. This assessment is certainly very important for the evaluation of therapeutic treatment in relation to the severity of the diseas

PHYTOTHERAPEUTIC TREATMENT OF ALLERGIC RHINITIS IN AUTISTIC SUBJECT

In this study the efficacy of a nasal spray based on extract of lemon pulp for treatment of allergic rhinitis in autistic subjects by nasal cytology was evaluated. The extract of lemon pulp was obtained by means of an innovative technology of solid-liquid extraction using Extractor Naviglio or Rapid Solid-Liquid Dynamic Extractor, that can extracts vegetable matrices of each species, by using different types of solvents (organic and/or inorganic liquids). Due to pressure-depressure action, by using water as extractive liquid it is possible to extract both hydrophilic and lipophilic substances contained in vegetables. The efficacy of the lemon based nasal spray has been tested on 20 young patients aged between three and eight years (10 males and 10 females, mean age 5.5 years). The cytology was performed by exfoliative technique, with a sterile swab soaked in sterile saline solution and then crawled on the middle part of the inferior turbinate. The collected sample was stained with the method of May-Giemsa Grumwald to highlight the morphological changes of the nasal epithelium before and after therapy based on nasal spray. Experimental data demonstrated that the anti-inflammatory effect of the lemon based nasal spray was a safe medical device as an aid in the reduction of inflammatory cells observed on rinocitogram. The lemon based nasal spray containing extract of lemon pulp can be used in all autistic patients, even in children, given the absence of alcohol

A Phytotherapic Formulation for Allergic Rhinitis in Autistic Children

In this study, the efficacy of a nasal spray based on lemon pulp extract for the treatment of allergic rhinitis in autistic subjects was evaluated by nasal cytology. The lemon pulp extract was obtained using an innovative solid-liquid extraction technology using a Naviglio Extractor or a Rapid Solid-Liquid Dynamic Extractor (RSLDE) that extracts vegetable matrices from different species by using different types of solvents. Due to the pressurising and depressurising of this technique and using water as a solvent, it is possible to extract both the hydrophilic and lipophilic substances contained in vegetables in a heterogeneous solution.We used a nasal spray based on a lemon pulp extract for the treatment of allergic rhinitis in autistic subjects, for whom there are legal limitations regarding the possible harmful side effects associated with the long-term use of traditional treatments, such as the use of cortisone, antihistamines, and leukotriene modifiers. Moreover, this nasal spray can be administered to very young children because it contains no alcohol.The experimental data demonstrated that the lemon-based nasal spray has antiinflammatory effects and is therapeutically safe as an aid in reducing the inflammatory cells observed in the nasal cytology.Nasal cytology was performed using an exfoliative technique with a sterile swab soaked in sterile saline solution and then rubbed on the middle part of the inferior turbinate. The collected sample was May-Giemsa Grumwald stained to highlight the morphological changes in the nasal epithelium before and after the nasal spray therapy

Applications of chitosan as a functional food

Chitosan is the most common natural polymer after natural cellulose. It is obtained by deacetylating chitin and has many versatile uses because of its solubility in weak acids; it can be used to produce biodegradable adhesive films, fibers of different thicknesses obtained by means of electrospinning, functional hydrogels, nanoemulsions and nanoparticles for functions such as the packaging of active substances for controlled release administration, and other derivatives with great potential, in addition to its use in mineral complexing. The range of possible applications is very broad, from food to the environment, agriculture, pharmaceuticals, medical products, textiles, and cosmetics, and it is used not only for its chemical and physical characteristics but also for its antimicrobial, antibacterial, wound-healing, lipid-lowering, anti-inflammatory, antiatherosclerosis, and anticancer properties. Its nontoxicity allows chitosan to be used long term as a soluble dietary fiber to improve digestion and aid the development of intestinal microflora with significant benefits to the health of the organism

Effects of the Silica Dust on the Nasal Mucosa of Ceramic Workers

Background. Adverse health effects due to occupational exposures are a global public health concern and have been studied for many years. Ceramic workers are occupationally exposed to a wide range of toxic substances as they manage clay (silico-aluminous feldspar mixed with sodium, potassium salts and iron oxide). The objective of this study was to assess the presence of any inflammation or alteration of the nasal mucosa of ceramic workers by nasal cytology. Materials and methods. Twenty-eight ceramic workers from Caltagirone (Italy) were enrolled. Nasal symptoms, atopy, health habits and workplace features were assessed by a special questionnaire, and nasal mucosa health was evaluated by nasal cytology. Results. The cytological study of the nasal mucosa revealed the constant presence of abundant, thick and filamentous mucus, as well as a reorganization of the nasal cellularity with a prevalence of muciparous hyperplasia and metaplasia in the study group, and only in a lesser extent for the subjects with some protective environmental measures. Conclusions. The ceramic workers showed chronic inflammatory rhinitis on nasal cytology, with a remodelling of the nasal mucosa and thick mucus. Nasal cytology may be a helpful tool either for the health surveillance of the ceramic workers, or for the screening of any pathology of the upper airways

Benign Paroxysmal Positional Vertigo (BPPV) and microvasculitis: A comparative study between nasal cytology and pathology

Purpose: Benign paroxysmal positional vertigo (BPPV) is the most frequent peripheral vertigo syndrome in otoneurological clinical practice and is characterized by short and paroxysmal objective vertigo crises caused by changes in the position of the head on specific planes of space. Secondary microvasculitis is characterized by inflammatory destruction of the small vessels. Starting from this point, this work is based on the research of correlation between microvasculitis (especially secondary), recurrent BPPV and nasal cytology, an aspect, among other things, poorly documented. Materials and methods: To evaluate the relationships between recurrent BPPV and secondary microvasculitis, nine patients with this disorder, 5 males and 4 females aged between 25 and 40 years were observed (average age 30.6). Non allergic pains in the small joints and in the anamnesis nothing relevant in the gentiles and collaterals: Evaluated with vestibular audiometric examination, nasal cytology and vascular examination with corneal HRT results. Nasal cytology, in all cases, has documented the presence of rare mast cells. The hemodynamics of the microcirculation with a confocal microscope has revealed blood flow alteration in all subjects. Discussion: Analyzing the results, both the prevalence of the right side and a close relationship between vasculitis and BPPV could be seen. Conclusion: The study of the nasal mucosa and the research of inflammatory cells could be fundamental for the study of BPPV in which as we have seen the important biochemical role for the onset of these diseases