12 research outputs found
Genomic Exploration of the Hemiascomycetous Yeasts: 19. Ascomycetes-specific genes
AbstractComparisons of the 6213 predicted Saccharomyces cerevisiae open reading frame (ORF) products with sequences from organisms of other biological phyla differentiate genes commonly conserved in evolution from âmaverickâ genes which have no homologue in phyla other than the Ascomycetes. We show that a majority of the âmaverickâ genes have homologues among other yeast species and thus define a set of 1892 genes that, from sequence comparisons, appear âAscomycetes-specificâ. We estimate, retrospectively, that the S. cerevisiae genome contains 5651 actual protein-coding genes, 50 of which were identified for the first time in this work, and that the present public databases contain 612 predicted ORFs that are not real genes. Interestingly, the sequences of the âAscomycetes-specificâ genes tend to diverge more rapidly in evolution than that of other genes. Half of the âAscomycetes-specificâ genes are functionally characterized in S. cerevisiae, and a few functional categories are over-represented in them
Genomic exploration of the hemiascomycetous yeasts: 5. Saccharomyces bayanus var. uvarum
International audienc
Genomic exploration of the hemiascomycetous yeasts: 14. Debaryomyces hansenii var. hansenii
International audienc
Genomic exploration of the hemiascomycetous yeasts: 17. Yarrowia lipolytica
International audienc
Identification of putative parasitism genes in plant-parasitic nematodes
Online proceedings URL:
http://www.pasteur.fr/ip/easysite/pasteur/fr/recherche/communication-scientifique/conferences-et-congres-scientifiques/conferences-service-colloques-institut-pasteur/jobim-2011/programme/actesstatus: publishe
Genomic exploration of the hemiascomycetous yeasts: 19. Ascomycetes-specific genes
International audienc
Genomic exploration of the hemiascomycetous yeasts: I. A set of yeast species for molecular evolution studies
International audienc
Genomic exploration of the hemiascomycetous yeasts: 18. Comparative analysis of chromosome maps and synteny with Saccharomyces cerevisiae
International audienc
Mosaic parental germline mutations causing recurrent forms of malformations of cortical development
International audienc
Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita
Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wallâdegrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.This article is published as Abad, Pierre, JĂ©rĂŽme Gouzy, Jean-Marc Aury, Philippe Castagnone-Sereno, Etienne GJ Danchin, Emeline Deleury, Laetitia Perfus-Barbeoch et al. "Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita." Nature biotechnology 26, no. 8 (2008): 909-915, doi: 10.1038/nbt.1482. Posted with permission.</p