A Compressed Sensing Algorithm for Sparse-View Pinhole Single Photon Emission Computed Tomography

Single Photon Emission Computed Tomography (SPECT) systems are being developed with multiple cameras and without gantry rotation to provide rapid dynamic acquisitions. However, the resulting data is angularly undersampled, due to the limited number of views. We propose a novel reconstruction algorithm for sparse-view SPECT based on Compressed Sensing (CS) theory. The algorithm models Poisson noise by modifying the Iterative Hard Thresholding algorithm to minimize the Kullback-Leibler (KL) distance by gradient descent. Because the underlying objects of SPECT images are expected to be smooth, a discrete wavelet transform (DWT) using an orthogonal spline wavelet kernel is used as the sparsifying transform. Preliminary feasibility of the algorithm was tested on simulated data of a phantom consisting of two Gaussian distributions. Single-pinhole projection data with Poisson noise were simulated at 128, 60, 15, 10, and 5 views over 360 degrees. Image quality was assessed using the coefficient of variation and the relative contrast between the two objects in the phantom. Overall, the results demonstrate preliminary feasibility of the proposed CS algorithm for sparse-view SPECT imaging

The Performance of MLEM for Dynamic Imaging From Simulated Few-View, Multi-Pinhole SPECT

Stationary small-animal SPECT systems are being developed for rapid dynamic imaging from limited angular views. This work quantified, through simulations, the performance of Maximum Likelihood Expectation Maximization (MLEM) for reconstructing a time-activity curve (TAC) with uptake duration of a few seconds from a stationary, three-camera multi-pinhole SPECT system. The study also quantified the benefits of a heuristic method of initializing the reconstruction with a prior image reconstructed from a conventional number of views, for example from data acquired during the late-study portion of the dynamic TAC. We refer to MLEM reconstruction initialized by a prior-image initial guess (IG) as MLEMig. The effect of the prior-image initial guess on the depiction of contrast between two regions of a static phantom was quantified over a range of angular sampling schemes. A TAC was modeled from the experimentally measured uptake of 99mTc-hexamethylpropyleneamine oxime (HMPAO) in the rat lung. The resulting time series of simulated images was quantitatively analyzed with respect to the accuracy of the estimated exponential washin and washout parameters. In both static and dynamic phantom studies, the prior-image initial guess improved the spatial depiction of the phantom, for example improved definition of the cylinder boundaries and more accurate quantification of relative contrast between cylinders. For example in the dynamic study, there was ~ 50% error in relative contrast for MLEM reconstructions compared to ~ 25-30% error for MLEMig. In the static phantom study, the benefits of the initial guess decreased as the number of views increased. The prior-image initial guess introduced an additive offset in the reconstructed dynamic images, likely due to biases introduced by the prior image. MLEM initialized with a uniform initial guess yielded images that faithfully reproduced the time dependence of the simulated TAC; there were no s- atistically significant differences in the mean exponential washin/washout parameters estimated from MLEM reconstructions compared to the true values. Washout parameters estimated from MLEMig reconstructions did not differ significantly from the true values, however the estimated washin parameter differed significantly from the true value in some cases. Overall, MLEM reconstruction from few views and a uniform initial guess accurately quantified the time dependance of the TAC while introducing errors in the spatial depiction of the object. Initializing the reconstruction with a late-study initial guess improved spatial accuracy while decreasing temporal accuracy in some cases

Modular Autonomous Biosampler (MAB)- A prototype system for distinct biological size-class sampling and preservation

Presently, there is a community wide deficiency in our ability to collect and preserve multiple size-class biologic samples across a broad spectrum of oceanographic platforms (e.g. AUVs, ROVs, and Ocean Observing System Nodes). This is particularly surprising in comparison to the level of instrumentation that now exists for acquiring physical and geophysical data (e.g. side-scan sonar, current profiles etc.), from these same platforms. We present our effort to develop a low-cost, high sample capacity modular,autonomous biological sampling device (MAB). The unit is designed for filtering and preserving 3 distinct biological size-classes (including bacteria), and is deployable in any aquatic setting from a variety of platform modalities (AUV, ROV, or mooring)

Correction of Bathymetric Survey Artifacts Resulting from Apparent Wave-Induced Vertical Position of an AUV

Recent increases in the capability and reliability of autonomous underwater vehicles (AUVs) have provided the opportunity to conduct bathymetric seafloor surveys in shallow water (\u3c 50 m). Unfortunately, surveys of this water depth may contain artifacts induced by large amplitude wave motion at the surface. The artifacts occur when an onboard pressure sensor determines the depth of the AUV. Waves overhead induce small pressure fluctuations at depth, which modulate the AUV’s pressure sensor output without causing actual vertical movement of the AUV. Since bathymetric measurements are made with respect to the AUV’s depth, these pressure fluctuations, in turn, modulate the measurement of the seafloor. The result is a periodic across-track, vertical offset of the seafloor profile (similar to a heave artifact sometimes common in surface vessel surveys). In this paper we describe our experience with the “Gavia” model AUV (Hafmynd EHF, Iceland) in a recent bathymetric survey during which wave action overhead induced such an artifact with a peak-to-peak amplitude as large as 1 meter. A method for removing the artifact as well as recommendations for modifications to the sonar, INS and AUV to mitigate the effect in the future are provided

Designing Improved Sediment Transport Visualizations

Monitoring, or more commonly, modeling of sediment transport in the coastal environment is a critical task with relevance to coastline stability, beach erosion, tracking environmental contaminants, and safety of navigation. Increased intensity and regularity of storms such as Superstorm Sandy heighten the importance of our understanding of sediment transport processes. A weakness of current modeling capabilities is the ability to easily visualize the result in an intuitive manner. Many of the available visualization software packages display only a single variable at once, usually as a two-dimensional, plan-view cross-section. With such limited display capabilities, sophisticated 3D models are undermined in both the interpretation of results and dissemination of information to the public. Here we explore a subset of existing modeling capabilities (specifically, modeling scour around man-made structures) and visualization solutions, examine their shortcomings and present a design for a 4D visualization for sediment transport studies that is based on perceptually-focused data visualization research and recent and ongoing developments in multivariate displays. Vector and scalar fields are co-displayed, yet kept independently identifiable utilizing human perception\u27s separation of color, texture, and motion. Bathymetry, sediment grain-size distribution, and forcing hydrodynamics are a subset of the variables investigated for simultaneous representation. Direct interaction with field data is tested to support rapid validation of sediment transport model results. Our goal is a tight integration of both simulated data and real world observations to support analysis and simulation of the impact of major sediment transport events such as hurricanes. We unite modeled results and field observations within a geodatabase designed as an application schema of the Arc Marine Data Model. Our real-world focus is on the Redbird Artificial Reef Site, roughly 18 nautical miles offshor- Delaware Bay, Delaware, where repeated surveys have identified active scour and bedform migration in 27 m water depth amongst the more than 900 deliberately sunken subway cars and vessels. Coincidently collected high-resolution multibeam bathymetry, backscatter, and side-scan sonar data from surface and autonomous underwater vehicle (AUV) systems along with complementary sub-bottom, grab sample, bottom imagery, and wave and current (via ADCP) datasets provide the basis for analysis. This site is particularly attractive due to overlap with the Delaware Bay Operational Forecast System (DBOFS), a model that provides historical and forecast oceanographic data that can be tested in hindcast against significant changes observed at the site during Superstorm Sandy and in predicting future changes through small-scale modeling around the individual reef objects

The Lighthouse Song / music by Charles Dennee; words by Allen Lowe

Cover: drawing of a ship and a Lighthouse; Publisher: Arthur P. Schmidthttps://egrove.olemiss.edu/sharris_b/1035/thumbnail.jp

Understanding and Treating the Psychosocial Consequences of Infertility

Psychological distress and infertility are linked in a complex pattern, such that distress may be a cause of infertility and reduce the probability of achieving a pregnancy at the same time that infertility may be a cause of psychological distress. Although infertile women are not more likely to be characterized by psychopathology, they are more likely to experience higher levels of distress than comparison groups. Infertile men also experience psychological distress, but women experience more infertility distress than men. Both infertility and its treatment are stressors putting a heavy psychological strain on couple relationships. Whereas there is general agreement about the need for psychological interventions to treat infertility distress, little is known about the efficacy and effectiveness of psychosocial intervention. Given the prevalence of infertility and the fact that the numbers of individuals and couples seeking infertility treatments are increasing, it is essential that mental health professionals understand the emotional challenges faced by this population.https://digitalcommons.chapman.edu/mft_books/1002/thumbnail.jp