16 research outputs found
Gravitational Radiation From Cosmological Turbulence
An injection of energy into the early Universe on a given characteristic
length scale will result in turbulent motions of the primordial plasma. We
calculate the stochastic background of gravitational radiation arising from a
period of cosmological turbulence, using a simple model of isotropic
Kolmogoroff turbulence produced in a cosmological phase transition. We also
derive the gravitational radiation generated by magnetic fields arising from a
dynamo operating during the period of turbulence. The resulting gravitational
radiation background has a maximum amplitude comparable to the radiation
background from the collision of bubbles in a first-order phase transition, but
at a lower frequency, while the radiation from the induced magnetic fields is
always subdominant to that from the turbulence itself. We briefly discuss the
detectability of such a signal.Comment: 20 pages. Corrections for an errant factor of 2 in all the gravity
wave characteristic amplitudes. Accepted for publication in Phys. Rev.
Bionutritional efficiency of crossbred beef cattle finished on feedlot andslaughtered at different body weights
Sincronização da onda folicular com hCG prévia à indução da luteólise com cloprostenol em bovinos
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Whole inactivated SIV virion vaccines with functional envelope glycoproteins: safety, immunogenicity, and activity against intrarectal challenge
Whole inactivated SIV virion vaccines with functional envelope glycoproteins: safety, immunogenicity, and activity against intrarectal challenge
An Assessment of the Role of Chimpanzees in AIDS Vaccine Research
Prior to Simian Immunodeficiency Virus (SIV)-infected macaques becoming the ‘model of choice’ in the 1990s, chimpanzees were widely used in AIDS vaccine research and testing. Faced with the continued failure to develop an effective human vaccine, some scientists are calling for a return to their widespread use. To assess the past and potential future contribution of chimpanzees to AIDS vaccine development, databases and published literature were systematically searched to compare the results of AIDS vaccine trials in chimpanzees with those of human clinical trials, and to determine whether the chimpanzee trials were predictive of the human response. Protective and/or therapeutic responses have been elicited in chimpanzees, via: passive antibody transfer; CD4 analogues; attenuated virus; many types and combinations of recombinant HIV proteins; DNA vaccines; recombinant adenovirus and canarypox vaccines; and many multi-component vaccines using more than one of these approaches. Immunogenicity has also been shown in chimpanzees for vaccinia-based and peptide vaccines. Protection and/or significant therapeutic effects have not been demonstrated by any vaccine to date in humans. Vaccine responses in chimpanzees and humans are highly discordant. Claims of the importance of chimpanzees in AIDS vaccine development are without foundation, and a return to the use of chimpanzees in AIDS research/vaccine development is scientifically unjustifiable