GO containing PHBHX bone scaffold: GO concentration and in vitro osteointegration

Trauma, congenital abnormalities or cancer-induced bone defects can be treated with tissue engineering products. Graphene oxide-containing polymeric scaffolds are used as an artificial extracellular matrix, acting as an environment where cells can grow and turn into living tissues. In the presented study, primarily cytotoxicity of graphene oxide was determined depending on the concentration. According to the cytotoxicity results, two different scaffolds containing low and high concentrations of GO were prepared and usability in bone tissue engineering was examined. For this purpose, water uptake, in vitro degradation and mechanical properties of the scaffolds were determined. On the predetermined days, MC3T3 cells proliferation and ACTB, COL1A1, OCN, OPN, RUNX2 gene expression were determined. According to the results, MC3T3 cell proliferation was increased when the incubation time increased, and also, gene expression related to bone tissue formation was increased. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature

Elazığ çevresinde ve Malatya GD'sunda yüzeyleyen yastık lavların petrolojisi, jeokronolojisi, izotop jeokimyası ve yastık lavlarla ilişkili pelajik çökellerin radyollarya faunasına bağlı olarak yaşlandırılması

TÜBİTAK ÇAYDAG01.05.201

Farklı yem bezelyesi (Pisum arvense) genotiplerinin tanelerinin yem içeriği yönünden karşılaştırılması

Islah materyalleri ve kültürü yapılan bitkiler; verim özelliği yönünden incelendiği gibi biotik ve abiotik stres koşullarına dayanıklılıkları yanında yem kalitesi gibi özellikleri bakımında da değerlendirilmelidir. Bu çalışmada 11 adet bezelye çeşit ve hatlarının tanelerinin besleme özellikleri yönünden karşılaştırılması amaçlanmıştır. Yapılan çalışma sonucunda yem bezelyeleri tanelerinin kimyasal kompozisyonları arasında oldukça farklılıklar gözlemlenmiştir. ADF oranı %8.35-14.34, NDF oranı %18.65-36.48, ham protein oranı %20.39-31.63, ham kül oranı %2.43-5.55, ham yağ oranı %1.27-1.87, sindirilebilir kuru madde oranı %77.73-82.39, kuru madde tüketimi %3.29-6.64 ve nispi yem değeri ise 209.30-404.17 arasında değişmiştir. Araştırma sonuçlarına göre gerek ıslah materyali olarak gerekse tarla tarımı için» materyal seçiminde amaca uygun seçimlerin yapılması çok önemli olduğu belirlenmiştir

Repair of acute Achilles tendon ruptures using Lynn method

Objectives: Efficiency assessment of Lynn method onopen primary repair of acute Achilles tendon ruptures.Methods: Data were evaluated from 19 patients whotreated with the Lynne method due to acute Achilles tendonrupture. Average follow-up length was 12.3 months(range 8-15 months). Dominant side was the right sideby all patients and all patients were males. Plantaris tendonaugmentation was applied after end-to-end repair bymodified Kessler suture technique.Results: The mean postoperative AOFAS score (TheAmerican Orthopaedic Foot and Ankle Society hindfootclinical outcome scores) was 93.5 (range 82-100). Theaverage of Achilles tendon postoperative assessmentscore, as developed by Thermann and colleagues, was93.3. Both assessment scores were between 90-100 andwere evaluated as very good. None of the patients developedpost-operative wound infection. The Thompson testwas negative on all patients and bilateral motor strengthwas 5/5.Conclusion: Lynn method, especially in young and activepatients with acute Achilles tendon rupture is a methodthat should be considered in treatment protocols.Key words: Achilles tendon, Lynn method, AOFAS scor

Yaygın fiğ (Vicia sativa L.) çeşitlerinin tohumlarının besleme değerleri

Bu çalışma, tescil edilmiş yaygın fiğ çeşitlerinin tanelerinin hayvan besleme yönünden farklılığını ortaya koymak amacıyla yapılmıştır. Çalışmada, 14 yaygın fiğ çeşidi tesadüf parselleri deneme desenine göre analiz edilmiştir. Analiz sonuçlarına göre; asit deterjan selülozu (ADF) oranı %7.47-14.19 arasında, nötral deterjan selülozu (NDF) oranı %16.84-29.25 arasında, ham protein oranı %24.45-31.69 arasında, ham kül oranı %2.53-2.82 arasında, sindirilebilir kuru madde %77.84-83.08 arasında, kuru madde tüketimi %4.10- 7.13 arasında.ve nispi yem değeri 260.14-449.40 arasında değişmiştir. Araştırma sonucunda; ham protein içeriği yönünden Dicle çeşidi, yüksek ADF oranı yönünden Soner çeşidi, düşük NDF içeriği, yüksek*kuru madde tüketimi ve nispi yem değeri yönünden Alınoğlu çeşidi ön plana çıkmıştır

Pelvic and retroperitoneal hydatid cysts superinfected with Brucella sp and review of infected hydatid cysts

WOS: 000316804600012PubMed ID: 23665713Hydatid disease is a zoonotic infection resulting from the tissue infestation of the larval stage of the parasite Echinococcus granulosus. Hydatid cysts superinfected with pyogenic organisms have been reported previously. Brucellosis is more prevalent in people with close contact to animals and those consuming fresh milk or fresh milk products. Although these two disorders have some similar epidemiological features, we did not encounter any hydatid cyst cases superinfected with Brucella species (sp.) in a search of medical literature (Pubmed). Here, we present a case of hydatid cyst disease superinfected with Brucella and review the literature on other hydatid cyst cases superinfected with pyogenic organisms. We conclude that in regions where brucellosis and hydatid cysts are endemic, cysts may be infected with Brucella sp

LATE CRETACEOUS ARC AND BACK-ARC FORMATION WITHIN THE SOUTHERN NEOTETHYS: WHOLE-ROCK, TRACE ELEMENT AND Sr-Nd-Pb ISOTOPIC DATA FROM BASALTIC ROCKS OF THE YUKSEKOVA COMPLEX (MALATYA- ELAZIG, SE TURKEY)

The remnants of the Southern Neotethys are represented by ophiolitic bodies and subduction/accretion complexes along the Southeast Anatolian-Zagros suture belt in the Eastern Mediterranean. Around Malatya and Elazig areas (SE Turkey), they are found within imbricated slices of a melange complex, known as the Yuksekova Complex. The studied basaltic rocks are common members of this melange complex, and show distinctive features of sources with tholeiitic to tholeiitic-transitional character. Petrography, whole-rock trace element and isotopic data reveal two different compositional groups. Group I is transitional between island arc tholeiites and normal mid-ocean ridge basalt, and Group II includes back-arc (BABB), enriched mid-ocean ridge (E-MORB), and ocean island basalt type (OIB) compositions. According to the known Late Cretaceous stratigraphic ages, the studied basaltic rocks have (Sr-87/Sr-86)(i) = 0.7036660-0.706394, (Nd-143/Nd-144), = 0.512734-0.512927, Pb-208/Pb-204 = 38.3216-39.3400, Pb-207/Pb-204 = 15.5018-15.6262 and Pb-206/Pb-204 = 18.5655-19.3209. In addition, epsilon Nd-i values vary between +3.99 and +8.01 with two-stage T-DM values ranging from 0.25 to 0.59 Ga. In the Sr versus Nd isotope correlation diagram, most samples plot along the mantle array line. In the correlation diagrams of Pb-206/Pb-204 versus Pb-208/Pb-206 and Pb-207/Pb-206, the rock samples also plot nearly on the Northern Hemisphere Reference Line, similar to Atlantic and Pacific Ocean ridge basalts. As a whole, the isotopic data reveal that the studied rocks were derived from a depleted mantle source

Upper Cretaceous Radiolarian ages from an arc-back-arc within the Yuksekova Complex in the southern Neotethys melange, SE Turkey

The Yuksekova complex in SE Turkey is a part of a continuous belt of ophiolites and subduction-accretion complexes that stretches from Troodos in the west to Oman in the east, representing the remnants of the Southern Branch of Neotethys. This complex mainly comprises a tectonically chaotic assemblage of basaltic dykes and pillow lavas associated with radiolarian cherts, shales and pelagic limestones. Detailed petrological work on submarine basaltic lavas from Elazig-Malatya area in SE Turkey revealed the presence of two distinct tectonomagmatic groups displaying island arc and back-arc characteristics. Radiolarian assemblages are described for the first time from radiolarian cherts in primary depositional contact with the basaltic rocks in this belt. Two distinct assemblages are recognized as Upper Cenomanian to Lower Turonian and Lower Coniacian to Lower Maastrichtian based on the characteristic radiolarian taxa. The new fossil data supports the suggestions that the southern branch of Neotethys has closed by intra-oceanic subduction where the arc and back-arc type oceanic crust generation was involved not earlier than Upper Cretaceous. (C) 2014 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved

Cervical Spinolaminoplasty With Newly Designed Titanium Mini-Plates

One of the complication of cervical laminoplasty is the restenosis of the opened laminae. Weakness of the screws placed on laminae may cause restenosis. Here, we describe a new technic 'spinolaminoplasty (Turkish Open-door laminoplasty)' with newly designed titanium mini plate that placed one side to lateral mass, and the other on spinous process to keep the laminae opened. Two different fixation materials were used for axial compression tests. One was Ultra high molecular weight polyethylene block with cervical vertebrae geometry and fresh ovine cervical vertebrae. In the first group, mini plates were fixed on laminae as in the conventional method described by Hirabayashi. In the second group, mini plates were fixed on spinous process to perform spinolaminoplasty with single and double screws. New fixation method with double screw provides 26% higher stiffness than the closest group, namely new fixation on polyethylene block. And new fixationmethod with double screw was exhibited significantly higher (P < 0.005) performance between the Ovine groups. As in the spinolaminoplasty technic fixing the mini plates to spinous process with longer screws instead of laminae, strengthens the system compared to the conventional method. This proves that rigidity of new construction model is more stable than the conventional method. Tight fixed laminae may prevent restenosis. Also applying the screw through spinous process instead of laminae may prevent the possible cord injuries.This work was supported by the Research Fund of TUBITAK, Project # 111M583, and Osimplant medical devices. Authors also would like to acknowledge to Mehmet Fatih Ormeci, Mehmet Akif Iyidiker and Akif Kaya Aybek for their valuable effort during tests and figure preparation