48 research outputs found

    Validade e reprodutibilidade de receptores para o GPS em relação à distância percorrida Validez y reproducibilidad de receptores GPS en relación de la distancia recorrida

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    ResumenObjetivoEl presente estudio evaluó la validez y reproducibilidad de dos modelos de receptores para el Global Positioning System (GPS). La validez fue evaluada comparando la distancia registrada por los receptores con la distancia conocida de estos trayectos.MétodoSeis jóvenes tenistas (177,6±6,2cm; 76,6±3,2kg) recorrieron tres trayectos: 1) 100m en la pista de atletismo (número de “disparos” = 120); 2) 400m en la pista de atletismo (número de “disparos” = 60) y 3) 100m con cambios de dirección (número de “disparos” = 120), utilizando los equipos Garmin© Forerunner 405 y Polar© RS800.ResultadosEn los trayectos sin cambios de dirección (100 y 400m), a través de la ANOVA two way (distancia y velocidad) no se detectaron diferencias entre la distancia conocida y las distancias registradas por los receptores analizados (p>0,05). En el trayecto de 100m con cambios de dirección, se observaron diferencias entre la distancia conocida y las registradas tanto por el Polar© RS800 como por el Garmin© Forerunner 405 (p<0,05). También se verificó la diferencia en las distancias registradas por el Polar® RS800 y por el Garmin© Forerunner 405 para el trayecto realizado con cambios de dirección (p<0,05).ConclusiónA través de los datos, se puede afirmar que los receptores para GPS evaluados presentaron un nivel aceptable de precisión para distancias recorridas sin cambios de dirección, sin embargo, la precisión de estos equipos en trayectos con cambios de dirección fue limitada.AbstractObjectiveThe present study evaluated the reproducibility and validity of two models of receivers for the Global Positioning System (GPS). Validity was assessed by comparing the distance recorded by the GPS receivers with the known distance.MethodSix young players (177.6±6.2cm; 76.6±3.2kg) performed three routes with different characteristics: 1) 100m in the athletics track (number of “sprints” = 120); 2) 400m in the athletics track (number of “sprints” = 60) and 3) 100m with changes of direction (number of “sprints” = 120), using equipment Garmin© Forerunner 405 and Polar© RS800.ResultsRegarding linear routes (100 and 400m), no differences were detected using ANOVA two-way (distance and speed) between the known distance and distance recorded by GPS receivers analyzed (p>0.05). Regarding non-linear route of, significant differences were observed between the known distance and recorded distance by the GPS receivers (p<0.05). There was also a significant difference between the distance recorded by Polar© RS800 and Garmin© Forerunner 405 for the non-linear route (p<0.05). Analysis of the limits of agreement reinforces the limitation of equipment in relation to accuracy for the non-linear route.ConclusionThese data suggest that the GPS receivers evaluated showed acceptable level of accuracy for linear routes, however, the accuracy of such devices on non-linear routes was limited

    Ação do cepa e do ácido giberélico na frutificação da videira 'niagara rosada'

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    Studies were carried out to establish the effects of exogenous growth regulators on Vitis (labrusca x vinifera) 'Niagara Rosada' fruiting. The investigations were done in the Jundiaí Research Station, Agronomic Institute State of São Paulo, always using disease-free vineyards of good productivity. The morphological transformations of clusters were carried out under the following aspects: weight, length and width of cluster; number of berries; weight, length average and width average of berries; length average/width average ratio of berries; number of seeds; length and diameter of secondary rachis. That characteristics were determined at the time of maturity plus the total sugars, total acid, Maturity Index and reducing sugars in samples of all treatments. The experiment were conduced in order to determine the doses that resulted in the most beneficial effects, always using applications by immersion of the inflorescence. The experiment consisted of appplications of (2-chloroethyl) phosphonic acid (CEPA) at concentrations of 50, 100, 250, 500, 1,000 and 2,000 ppm, 14 days before flowering; treatments with gibberellic acid at concentrations of 100 and 200 ppm before full bloom, 10 days after full bloom, and both before plus after full bloom. Treatment with CEPA 100 ppm plus gibberellic acid 100 ppm before full bloom and check treatment were also used. The use of CEPA before flowering at the concentrations used, did not result in good results in 'Niagara Rosada' clusters; applications of gibberellic acid did not differ significantly from the nontreated vines under the conditions studied.Estudou-se o efeito da aplicação, por imersão, do CEPA (ácido 2-cloroetil fosfônico) e do ácido giberélico, 14 dias antes do florescimento, nas características morfológicas da panícula da videira Vitis (labrus-ca x vinifera) "Niagara Rosada". Alguns tratamentos com ácido giberélico foram concluídos com nova aplicação 10 dias após o florescimento. Neste experimento verificou-se que, aplicação do CEPA na concentração de 250 ppm resultou na formação de panículas com a maioria de características indesejáveis. o tratamento misto CEPA 100 ppm + ácido giberélico 100 ppm também promoveu o aparecimento de panículas subdesenvolvidas. Aplicação de ácido giberélico na concentração de 100 ppm em pré e pós-ílorescimento, resultou médias mais elevadas, com relação ao peso da panícula, comprimento da panícula, peso das bagas e comprimento da ráquis. Ácido giberélico na concentração de 100 ppm aplicado em pós-ílorescimento, promoveu uma tendência de aumento nas médias do tratamento quanto ao comprimento médio das bagas, largura média das bagas, largura do engaço e comprimento da ráquila. Devemos considerar porém, que os resultados obtidos não apresentaram diferenças significativas com relação ao controle, quanto às características das frutificações, nas condições de estudo

    Atomic Spectrometry Based On Metallic Tube Atomizers Heated By Flame: Innovative Strategies From Fundamentals To Analysis

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    This review describes recent developments in atomic absorption spectrometry using metallic tube atomizers heated by flames. Sample introduction in spray or gaseous form is emphasized, describing some proposed systems for this task and the fundamentals involved in each context. The latest challenges and future possibilities for use of metallic tubes in atomic/mass spectrometry are also considered. © 2009 Elsevier B.V. All rights reserved.646477481Brancalion, M.L., Sabadini, E., Arruda, M.A.Z., Thermospray nebulization for flame furnace atomic absorption spectrometry - correlations between spray formation and cadmium analytical sensitivity (2009) Spectrochim. Acta Part B, 64, pp. 89-94Blank, P.C., De Loos-Vollebregt, M.T.C., De Galan, L., Flow-injection thermospray sample decomposition for electrothermal atomization atomic-absorption spectrometry (1988) Spectrochim. Acta Part B, 43, pp. 983-987Lefebvre, A.H., (1989) Atomization and Sprays, , Hemisphere Publishing Corp., New York, USAMontaser, A., Tan, H., Ishii, I., Nam, S.H., Cai, M., Argon inductively coupled plasma mass spectrometry with high efficiency nebulization (1991) Anal. Chem., 63, pp. 2660-2665Weber, A.P., Keil, R., Tobler, L., Baltensperger, U., Sensitivities of inductively coupled plasma optical-emission spectrometry for dry and wet aerosols (1992) Anal. Chem., 64, pp. 672-677Jankowski, K., Karmasz, D., Ramsza, A., Reszke, E., Characteristics of nebulizers for microwave-induced plasma atomic emission spectrometry - II: ultrasonic nebulizers (1997) Spectrochim. Acta Part B, 52, pp. 1813-1823Gáspár, A., Berndt, H., Beam injection flame furnace atomic absorption spectrometry: a new method (2000) Anal. Chem., 72, pp. 240-246Gáspár, A., Berndt, H., Thermospray flame furnace atomic absorption spectrometry (TS-FF-AAS) - a simple method for trace element determination with microsamples in the μg/l concentration range (2000) Spectrochim. Acta Part B, 55, pp. 587-597Wei, J., Shui, W., Zhou, F., Lu, Y., Chen, K., Xu, G., Naturally and externally pulsed electrospray (2002) Mass Spectrom. Rev., 21, pp. 148-162Grotti, M., Lagomarsino, C., Frache, R., A new nebulization device with exachangeable aerosol generation mode as a useful toll to investigate sample introduction process in inductively coupled plasma atomic emission spectrometry (2004) Spectrochim. Acta Part B, 59, pp. 1001-1006Conver, T.S., Yang, J., Koropchak, J.A., New developments in thermospray sample introduction for atomic spectrometry (1997) Spectrochim. Acta Part B, 52, pp. 1087-1104Dědina, J., Rubeska, L., Hydride atomization in a cool hydrogen-oxygen flame burning in a quartz tube atomizer (1980) Spectrochim. Acta Part B, 35, pp. 119-128Nascentes, C.C., Arruda, M.A.Z., Nogueira, A.R.A., Nóbrega, J.A., Direct determination of Cu and Zn in fruit juice and bovine milk by thermospray flame furnace atomic absorpition spectrometry (2004) Talanta, 64, pp. 912-917Nascentes, C.C., Kamogawa, M.Y., Fernandes, K.G., Arruda, M.A.Z., Nogueira, A.R.A., Nóbrega, J.A., Direct determination of Cu, Mn, Pb and Zn, in beer by thermospray flame furnace atomic absorption spectrometry (2005) Spectrochim. Acta Part B, 60, pp. 749-753Pereira-Filho, E.R., Berndt, H., Arruda, M.A.Z., Simultaneous sample digestion and determination of Cd, Cu and Pb in biological samples using thermospray flame furnace atomic absorption spectrometry (TS-FF-AAS) with slurry sample introduction (2002) J. Anal. At. Spectrom., 17, pp. 1308-1315Tarley, C.R.T., Figueiredo, E.C., Matos, G.D., Thermospray flame furnace - AAS determination of copper after on-line sorbent preconcentration using a system optimized by experimental designs (2005) Anal. Sci., 21, pp. 1337-1342Ribeiro, A.S., Arruda, M.A.Z., Cadore, S., Determination of bismuth in metallurgical materials using a quartz tube atomizer with tungsten coil and flow injection-hydride-generation atomic absorption spectrometry (2002) Spectrochim. Acta Part B, 57, pp. 2113-2120Ribeiro, A.S., Arruda, M.A.Z., Cadore, S., A quartz tube atomizer with tungsten coil: a new system for vapor atomization in atomic absorption spectrometry (2002) J. Anal. At. Spectrom., 17, pp. 1516-1522Figueiredo, E.C., Dědina, J., Arruda, M.A.Z., Metal furnace heated by flame as a hydride atomizer for atomic absorption spectrometry: Sb determination in environmental and pharmaceutical samples (2007) Talanta, 73, pp. 621-628Klassen, A., Kim, M.L., Tudino, M.B., Baccan, N., Arruda, M.A.Z., A metallic, furnace atomizer in hydride generation atomic absorption spectrometry: determination of bismuth and selenium (2008) Spectrochim. Acta Part B, 63, pp. 850-855Zhang, X., Chem, D., Marquardt, R., Koropchak, J.A., Thermospray sample introduction to atomic spectrometry (2000) Microchem. J., 66, pp. 17-53Blakley, C.R., McAdams, M.J., Vestal, M.L., Crossed-beam liquid chromatograph-mass spectrometer combination (1978) J. Chromatogr. A, 158, pp. 261-276Blakley, C.R., Carmody, J.J., Vestal, M.L., A new soft ionization technique for mass spectrometry of complex molecules (1980) J. Am. Chem. Soc., 102, pp. 5931-5933Vestel, M.L., Fergusson, G.J., Thermospray liquid chromatograph/mass spectrometer interface with direct electrical heating of the capillary (1985) Anal. Chem., 57, pp. 2373-2378Bordera, L., Todoli, J.L., Mora, J., Canals, A., Hermandis, V., A microwave-powered thermospray nebulizer for liquid sample introduction in inductively coupled plasma atomic emission spectrometry (1997) Anal. Chem., 69, pp. 3578-3586Koropchak, J.A., Veber, M., Thermospray sample introduction to atomic spectrometry (1992) Crit. Rev. Anal. Chem., 23, pp. 113-141Brancalion, M.L., Sabadini, E., Arruda, M.A.Z., Description of the thermospray formed at low flow rate in thermospray flame furnace atomic absorption spectrometry based on high-speed images (2007) Anal. Chem., 79, pp. 6527-6533Gottfried, B.S., Lee, C.J., Bell, K.J., Leidenfrost phenomenon - film boiling of liquid droplets on a flat plate (1966) Int. J. Heat Mass Transfer, 9, pp. 1167-1187C. Wares, (Translation), K.J. Bell, (Introduction), On the fixation of water in diverse fire, Int. J. Heat Mass Transfer 9(1966)1153-1166. Taken from J. G. Leidenfrost, A Tract About Some Qualities of WaterGermany, 1756http://gepam.iqm.unicamp.br/files/001.wmvBrancalion, M.L., Arruda, M.A.Z., Evaluation of medicinal plant decomposition efficiency using microwave ovens and mini-vials for Cd determination by TS-FF-AAS (2005) Microchim. Acta, 150, pp. 283-290Rosini, F., Nascentes, C.C., Neira, J.Y., Nóbrega, J.A., Evaluation of selenium behavior in thermospray flame furnace atomic absorption spectrometry (2007) Talanta, 73, pp. 845-849González, E., Ahumada, R., Medina, V., Neira, J., González, U., Espectrofotometría de absorción atómica con tubo en la llama: Aplicación en la determinación total de cadmio, plomo, y zinc en aguas frescas, agua de mar y sedimentos marinos (2004) Quim. Nova, 27, pp. 873-877Berndt, H., Pulvermacher, E., Sample introduction assisted by compressed air in flame furnace AAS: a simple and sensitive method for the determination of traces of toxic element (2005) Anal. Bioanal. Chem., 382, pp. 1826-1834Petrucelli, G.A., Poppi, R.J., Mincato, R.L., Pereira-Filho, E.R., TS-FF-AAS and multivariate calibration: a proposition for sewage sludge slurry sample analyses (2007) Talanta, 71, pp. 620-626Wu, P., Gao, Y., Cheng, G., Yang, W., Lv, Y., Hou, X., Selective determination of trace amounts of silver in complicated matrices by displacement-cloud point extraction coupled with thermospray flame furnace atomic absorption spectrometry (2008) J. Anal. At. Spectrom., 23, pp. 752-757Coelho, L.M., Bezerra, M.A., Arruda, M.A.Z., Bruns, R.E., Ferreira, S.L.C., Determination of Cd, Cu, and Pb after cloud point extraction using multielemental sequential determination by thermospray flame furnace atomic absorption spectrometry (TS-FF-AAS) (2008) Sep. Sci. Technol., 43, pp. 815-827Pereira, M.G., Pereira-Filho, E.R., Berndt, H., Arruda, M.A.Z., Determination of cadmium and lead at low levels by using preconcentration at fullerene coupled to thermospray flame furnace atomic absorption spectrometry (2004) Spectrochim. Acta Part B, 59, pp. 515-521Tarley, C.R.T., Arruda, M.A.Z., Online coupling of a flow injection system to TS-FF-AAS for preconcentration and determination of lead in water and vegetables (2005) Anal. Lett., 38, pp. 1427-1443Tarley, C.R.T., Arruda, M.A.Z., A simple method for cadmium determination using an on-line polyuretane foam preconcentration system and thermospray flame furnace atomic absorption spectrometry (2004) Anal. Sci., 20, pp. 961-966Lemos, V.A., Bezerra, M.A., Amorim, F.A.C., On-line preconcentration using a resin functionalized with 3,4-dihydroxybenzoic acid for the determination of trace elements in biological samples by thermospray flame furnace atomic absorption spectrometry (2008) J. Hazardous Mat., 157, pp. 613-619Amorim, F.A.C., Bezerra, M.A., Online preconcentration system for determining ultratrace amounts of Cd in vegetals samples using thermospray flame furnace atomic absorption spectrometry (2007) Microchim. Acta, 159, pp. 183-189Tarley, C.R.T., Barbosa, A.F., Segatelli, M.G., Figueiredo, E.C., Luccas, P.O., Highly improved sensitivity of TS-FF-AAS for Cd(II) determination at ng L- 1 levels using a simple flow injection minicolumn preconcentration system with multiwall carbon nanotubes (2006) J. Anal. At. Spectrom., 21, pp. 1305-1313Gáspár, A., Széles, E., Berndt, H., Analysis of submicroliter samples using micro thermospray flame furnace atomic absorption spectrometry (2002) Anal. Bioanal. Chem., 372, pp. 136-140Matos, G.D., Arruda, M.A.Z., Improvement in cobalt determination by thermospray flame furnace atomic absorption spectrometry using an on-line derivatization strategy (2008) Talanta, 76, pp. 475-478Yavuz Ataman, O., Vapor generation and atom traps: atomic absorption spectrometry at the ng/L level (2008) Spectrochim. Acta Part B, 63, pp. 825-834Moretto, A.L., Cadore, S., Determination of arsenic in food samples by hydride generation-atomic absorption spectrometry (2004) Microchim. Acta, 146, pp. 239-244Yersel, M., Erdem, A., Eroǧlu, A.E., Shahwan, T., Separation of trace antimony and arsenic prior to hydride generation atomic absorption spectrometric determination (2005) Anal. Chim. Acta, 534, pp. 293-300Karanassios, V., Grishko, V., Reynolds, G.G., Elemental analysis of micro-samples of liquids or slurries by coiled-filament in-torch vaporization-inductively coupled plasma atomic emission spectrometry (ITV-ICP-AES) (1999) J. Anal. At. Spectrom., 14, pp. 565-570Badiei, H.R., Karanassios, V., Rhenium-cup in-torch vaporization inductively coupled plasma atomic emission spectrometry for liquid, slurry or solid micro-samples (2000) J. Anal. At. Spectrom., 15, pp. 1057-1062Badiei, H.R., Rutzke, M.A., Karanassios, V., Calcium content of individual, microscopic, (sub) nanoliter volume Paramecium sp. cells using rhenium-cup in torch vaporization (ITV) sample introduction and axially viewed ICP-AES (2002) J. Anal. At. Spectrom., 17, pp. 1007-1010Gibson, B., Badiei, H.R., Karanassios, V., Ti in dilute slurries of TiO2 nanoparticles by in-torch vaporization sector field inductively coupled plasma-mass spectrometry (2006) Spectrochim. Acta Part B, 61, pp. 753-75

    Molecular Imprinting: A Promising Strategy In Matrices Elaboration For Drug Delivery Systems [impressão Molecular: Uma Estratégia Promissora Na Elaboração De Matrizes Para A Liberação Controlada De Fármacos]

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    Biomolecular interactions (antigen-antibody, enzymesubstrate and drug-receptor) have been investigated due to their selective nature. Thus, since 1940, the search for synthetic materials presenting specific binding sites has been increasing. Nowadays, they are well established in different science areas such as pharmacy, analytical chemistry, biochemistry, among others, being the referred materials called molecularly imprinted polymers-MIP. Although the largest applications of MIP are found in the separations science field, few applications of these polymers have been reported as drug delivery systems-DDS. Such applications have been promising due to the feasibility of the MIP synthesis. However, the clinical use of the MIP as DDS is still not observed, probably due to its recent application, as well as extensive tests necessary for its approval as a new pharmaceutical form. In this way, this work aims to present the most recent progresses in the use of MIP as DDS, reinforcing the most significant aspects of this application (potentialities and limitations), as well as classifying and detailing such systems.443361375ALLENDER, C.J., RICHARDSON, C., WOODHOUSE, B., HEARD, C.M., BRAIN, K.R., Pharmaceutical applications for molecularly imprinted polymers (2000) Int. J. Pharm, 195 (1-2), pp. 39-43ALVAREZ-LORENZO, C., CONCHEIRO, A., Molecularly imprinted polymers for drugs delivery (2004) J. Chromatogr., B: Anal. Technol. Biomed. Life Sci, 804 (1), pp. 231-245ALVAREZ-LORENZO, C., GUNEY, O., OYA, T., SAKAI, Y., KOBAYASHI, M., ENOKI, T., TAKEOKA, Y., GROSBERG, A.Y., Reversible adsorption of calsium ions by imprinted temperature sensitive gels (2001) J. Chem. Phys, 114 (6), pp. 2812-2816ALVAREZ-LORENZO, C., YAÑEZ, F., BARREIROIGLESIAS, R., CONCHEIRO, A., Imprinted soft contact lenses as norfloxacin delivery systems (2006) J. Control. Release, 113 (3), pp. 236-244ANDERSSON, L., SELLERGREN, B., MOSBACH, K., Imprinting of amino acid derivatives in macroporous polymers (1984) Tetrahedron Lett, 25 (45), pp. 5211-5214ARSHADY, R., MOSBACH, M., Synthesis of substrate-selective polymers by host-guest polymerization (1981) Macromol. Chem. Phys, 182 (2), pp. 687-692AYDIN, O., ATTILA, G., DOGAN, A., AYDIN, M.V., CANACANKATAN, N., KANIK, A., The effects of methyl methacrylate on nasal cavity, lung, and antioxidant system (an experimental inhalation study) (2002) Toxicol. Pathol, 30 (3), pp. 350-356AZEVEDO, M.M.M. Nanoesfereas e a liberação controlada de fármacos. In: WORKSHOP DO CURSO: TÓPICOS ESPECIAIS EM QUÍMICA INORGÂNICA IV - INTRODUÇÃO À NANOTECNOLOGIA: UM ENFOQUE QUÍMICO, 1, Campinas, 2002. Disponível em: 〈http://lqes.iqm.unicamp.br/images/ vivencia_lqes_monografias_marcelo_nanoesferas.pdf〉. Acesso em: 08 maio 2007BERZELIUS, J.J., (1835) Jahresber. Chem, 15, pp. 242-244CHEN, G., GUAN, Z., CHEN, C., FU, L., SUNDARESAN, V., ARNALD, F.H., A glucose-sensing polymer (1997) Nat. Biotechnol, 15 (4), pp. 354-357CHIEN, Y.W., LIN, S., Optimisation of treatment by applying programmable rate-controlled drug delivery technology (2002) Clin. Pharmacokinet, 41 (15), pp. 1267-1300CHUNG, J.E., YOKOYAMA, M., OKANO, T., Inner core segment design for drug delivery control of thermoresponsive polymeric micelles (2000) J.Control. Release, 65 (1-2), pp. 93-103CIARDELLI, G., CIONI, B., CRISTALLINI, C., BARBANI, N., SILVESTRI, D., GIUSTI, P., Acrylic polymeric nanospheres for the release and recognition of molecules of clinical interest (2004) Biosens. Bioelectron, 20 (6), pp. 1083-1090CORMACK, P.A.G., ELORZA, A.Z., Molecularly imprinted polymers: Synthesis and characterization (2004) J. Chromatogr., B: Anal. Technol. Biomed. Life Sci, 804 (1), pp. 173-182CUNLIFFE, D., KIRBY, A., ALEXANDER, C., Molecularly imprinted drug delivery systems (2005) Adv. Drug Deliv. Rev, 57 (12), pp. 1836-1853DICKEY, F.H., The preparation of specific adsorbents (1949) Proc. Natl. Acad. Sci, 35 (5), pp. 227-229N.DE AZEVEDO, M.M. O que é nanotecnologia? Atualidades e perspectivas, , http://www.ifi.unicamp.br/extensao/downloads/nanobiotecnologia.doc〉.Acesso, DURÁN, Disponível em:, 15 jun. 2007FIUME, M.Z., Final report on the safety assessment of acrylates copolymer and 33 related cosmetic ingredients (2002) In. J. Toxicol, 21 (3), pp. 1-50GLAD, M., REINHOLDSSON, P., MOSBACH, K., Molecularly imprinted composite polymers based on trimethylolpropane trimethacrylate (TRIM) particles for efficient enantiomeric separations (1995) React. Poly, 25 (1), pp. 47-54GRAYSON, A.C.R., CHOI, I., TYLER, B.M., WANG, P.P., BREM, H., CIMA, M.J., LANGER, R., Multi-pulse drug delivery from a resorbable, polymeric microchip device (2003) Nat. Mater, 2 (11), pp. 767-772HAGINAKA, J., Monodispersed, molecularly imprinted polymers as affinity-based chromatography media (2008) J. Chromatogr., B: Anal. Technol. Biomed. Life Sci, 866 (1-2), pp. 3-13HAGINAKA, J., SANBE, H., TAKEHIRA, H., Uniformsized molecularly imprinted polymer for (S)-ibuprofen retention properties in aqueous mobile phases (1999) J. Chromatogr., A, 857 (1-2), pp. 117-125HILLBERG, A.L., BRAIN, K.R., ALLENDER, C.J., Molecular imprinted polymer sensors: Implications for therapeutics (2005) Adv. Drug Deliv. Rev, 57 (12), pp. 1875-1889HILT, J.Z., BYRNE, M.E., Configurational biomimesis in drug delivery: Molecular imprinting of biologically significant molecules (2004) Adv. Drug Delivery Rev, 56 (11), pp. 1599-1620HIRATANI, H., ALVAREZ-LORENZO, C., Timolol uptake and release by imprinted soft contact lenses made of N,N-dimethylacrylamine and methacrylic acid (2002) J. Control. Release, 83 (2), pp. 223-230HIRATANI, H., FUJIWARA, A., TAMIYA, Y., MIZUTANI, Y., ALVAREZ-LORENZO, C., Ocular release of timolol from molecularly imprinted soft contact lenses (2005) Biomaterials, 26 (11), pp. 1293-1298HIROKAWA, Y., TANAKA, T., Volume phase transition in a nonionic gel (1984) J. Chem. Phys, 81 (12), pp. 6379-6380HOFFMAN, A.S., Applications of thermally reversible polymers and hydrogels in therapeutics and diagnostics (1987) J. Control. Release, 6 (1), pp. 297-305JANTARAT, C., TANGTHONG, N., SONGKRO, S., MARTIN, G.P., SUEDEE, R., S-Propranolol imprinted polymer nanoparticle-on-microsphere composite porous cellulose membrane for the enantioselectively controlled delivery of racemic propranolol (2008) Int. J. Pharm, 349 (1-2), pp. 212-225KAPARISSIDES, C., ALEXANDRIDOU, S., KOTTI, K., CHAITIDOU, S., Recent advances in novel drug delivery systems (2006) J. Nanotechynol. Online, 2, pp. 1-11KARLSSON, J.G., ANDERSSON, L.I., NICHOLLS, I.A., Probing the molecular basis for ligand-selective recognation in molecularly imprinted polymers for the local anesthetic bupivacaine (2001) Anal. Chim. Acta, 435 (1), pp. 57-64KARMALKAR, R.N., KULKARNI, M.G., MASHELKAR, R.A., Pendent chain linked delivery systems: II. Facile hydrolysis through molecular imprinting effects (1997) J. Control. Release, 43 (2-3), pp. 235-243KATAOKA, K.MIYAZAKI, H.BUNYA, M.OKANO, T.SAKURAI, Y. On-off regulation of insulin-release by totally synthetic polymer gels responding to external glucose concentration. Polym. Prepr., Abstracts of Papers of the American Chemical Society, v.217, n.165-Poly, p.U564-U564, 1999KHAJEH, M., YAMINI, Y., GHASEMI, E., FASIHI, J., SHAMSIPUR, M., Imprinted polymer particles for selenium uptake: Synthesis, characterization and analytical applications (2007) Anal. Chim. Acta, 581 (2), pp. 208-213KIM, I.S., JEONG, Y.I., CHO, C.S., KIM, S.H., Core-shell type polymeric nanoparticles composed of poly(L-lactic acid) and poly(N- isopropylacrylamide (2000) Int. J. Pharm, 211 (1-2), pp. 1-8LEE, W.F., YEN, S.H., Thermoreversible hydrogels. XII. Effect of the polymerization conditions on the swelling behavior of the N-isopropylacrylamide gel (2000) J. Appl. Polym. Sci, 78 (9), pp. 1604-1611LIMBIRD, L.E., The Receptor Concept: A Continuing Evolution (2004) Mol. Interv, 4, pp. 326-336MAGALHÃES, C.S., GARCIA, J.S.LOPES, A.S.FIGUEIREDO, E.C.ARRUDA, M.A.Z. Strategies for sample preparation focusing on biomolecules determination/caracterization In: ARRUDA, M.A.Z. (Eds.). Trends in sample preparation. New York: Nova Science Publishers, 2007. cap.9, p.245-288MARTÍN-ESTEBAN, A., Molecularly imprinted polymers: New molecular recognation materials for selective solid-phase extraction of organic compounds (2001) Fresenius J. Anal. Chem, 370 (7), pp. 795-802MATSUI, J., OKADA, M., TSURUOKA, M., TAKEUCHI, T., Solid-phase extraction of a triazine herbicide using a molecularly imprinted synthetic receptor (1997) Anal. Commun, 34 (3), pp. 85-87MAYES, A.G., MOSBACH, K., Molecularly imprinted polymer beads: Suspension polymerization using a liquid perfluorocarbon as the dispersing phase (1996) Anal. Chem, 68 (21), pp. 3769-3774MIYATA, T., URAGAMI, T., NAKAMAE, K., Biomolecule-sensitive hydrogels (2002) Adv. Drug Del. Rev, 54 (1), pp. 79-98MORITANI, T., ALVAREZ-LORENZO, C., Conformational imprinting effect on stimuli-sensitive gels made with an "imprinter" monomer (2001) Macromolecules, 34 (22), pp. 7796-7803NICHOLLS, I.A., ADBO, K., ANDERSSON, H.S., ANDERSSON, P.O., ANKARLOO, J., HEDINDAHLSTROM, J., JOKELA, P., WIKMAN, S., Can we rationally design molecularly imprinted polymers? (2001) Anal. Chim. Acta, 435 (1), pp. 9-18NORELL, M.C., ANDERSSON, H.S., NOCHOLLS, I.A., Theophylline molecularly imprinted polymer dissociation kinetics: A novel sustained realease drug dosage mechanism (1998) J. Mol. Recog, 11 (1-6), pp. 98-102OKANO, T., BAE, Y.H., JACOBS, H., KIM, S.W., Thermally on-off switching polymers for drug permeation and release (1990) J. Control. Release, 11 (1-3), pp. 255-265PAULING, L.J., A Theory of the structure and process of formation of antibodies (1940) J. Am. Chem. Soc, 62 (10), pp. 2643-2657PHILIP, J.Y.N., BUCHWEISHAIJA, J., MKAYULA, L.L., YE, L., Preparation of molecularly imprinted polymers using anacardic acid monomers derived from cashew nut shell liquid (2007) J. Agric. Food Chem, 55 (22), pp. 8870-8876PUOCI, F., IEMMA, F., CIRILLO, G., PICCI, N., MATRICARDI, P., ALHAIQUE, A., Molecularly Imprinted Polymers for 5-Fluorouracil Release in Biological Fluids (2007) Molecules, 12 (4), pp. 805-814PUOCI, F., IEMMA, E., MUZZALUPO, R., SPIZZIRRI, U.G., TROMBINO, S., CASSANO, R., PICCI, N., Spherical Molecularly Imprinted Polymers (SMIPs) via a Novel Precipitation Polymerization in the Controlled Delivery of Sulfasalazine (2004) Macromol. Biosc, 4 (1), pp. 22-26RAMSTRÖM, O., ANDERSSON, L.I., MOSBACH, K., Recognition sites incorporating both pyridinyl and carboxy functionalities prepared by molecular imprinting (1993) J. Org. Chem, 58 (26), pp. 7562-7564RICKA, J., TANAKA, T., Phase transition in ionic gels induced by copper complexation (1985) Macromol, 18 (1), pp. 83-85SANTINI Jr., J.T., CIMA, M.J., LANGER, R., A controlled-release microchip (1999) Nature, 397, pp. 335-338SELLERGREN, B., ALLENDER, C.J., Molecularly imprinted polymers: A bridge to advanced drug delivery (2005) Adv. Drug Delivery Rev, 57 (12), pp. 1733-1741SELLERGREN, B.HALL, A. J. Fundamental aspects on the synthesis and characterisation of imprinted network polymersIn: SELLERGREN, B. (Ed.). Molecularly imprinted polymers: Man-made mimics of antibodies and their applications in analytical chemistry. Amsterdam: Elsevier, 2001. cap.2, p. 21-57SELLERGREN, B., LEPISTÖ, M., MOSBACH, K., Highly Enantioselective and substrate-selective polymers obtained by molecular imprinting utilizing noncovalent interactions. NMR and chromatographic studies on the nature of recognition (1988) J. Am. Chem. Soc, 110 (17), pp. 5853-5860SREENIVASAN, K., Imparting cholesterol recognition sites in radiation polymerised poly(2-hydroxyethyl methacrylate) by molecular imprinting (1997) Polym. Int, 42 (2), pp. 169-172SREENIVASAN, K., On the aplication of molecularly imprinted poly(HEMA) as a template responsive realise system (1999) J. Appl. Polym, Sci, 71 (11), pp. 1819-1821STRIEGLER, S., Selective discrimination of closely related monosaccharides at physiological pH a polymeric receptor (2001) Tetrahedron, 57 (12), pp. 2349-2354STRIEGLER, S., Investigation of disaccharide recognition by molecularly imprinted polymers (2002) Bioseparation, 10 (6), pp. 307-314STRIEGLER, S., Carbohydrate recognition in cross-linked sugar-templated poly(acrylates) (2003) Macromol, 36 (4), pp. 1310-1317SUEDEE, R., SRICHANA, T., RATTANANONT, T., Enantioselective release of contolled delivery granules based on molecularly imprintd polymers (2002) Drug Delivery, 9 (1), pp. 19-30TARLEY, C.R.T., SOTOMAYOR, M.P.T., KUBOTA, L.T., Polímeros Biomiméticos em Química Analítica. Parte 1: Preparo e Aplicações de MIP (Molecularly Imprinted Polymers) em Técnicas de Extração e Separação. (2005) Quim. Nova, 28 (6), pp. 1076-1086THE UNITED STATES PHARMACOPEIA. 24. ed. Rockville: United States Pharmacopeial Convention, 2000. p.1577UCHIMURA, E., OTSUKA, H., OKANO, T., SAKURAI, Y., KATAOKA, K., Totally synthetic polymer with lectin-like function: Induction of killer cells by the copolymer of 3-acrylamidophenilboronic acid with n,ndimethylacrylamide (2001) Biotechnol. Bioeng, 72 (3), pp. 307-314ULUBAYRAM, K., TUNC, Y., BAYKARA, E., Molecularly imprinted acrylic-based microspheres for colonic delivery of 5-aminosalicylic acid (2007) J. Optoelectron. Adv. Mater, 9 (11), pp. 3479-3483VLATAKIS, G., ANDERSSON, L.I., MÜLLER, R., MOSBACH, K., Drug assay using antibody mimics made by molecularly imprinting (1993) Nature, 361, pp. 645-647WANG, J.F., CORMARCK, P.A.G., SHERRINGTON, D.C., KHOSHDEL, E., Monodisperse, molecularly imprinted polymer microspheres prepared by precipitation polymerization for affinity separation applications (2003) Angew. Chem, 42 (43), pp. 5336-5338WANG, X.B., DING, X.B., ZHENG, Z.H., HU, X.H., CHENG, X., PENG, Y.X., Magnetic molecularly imprinted polymer particles synthesized by suspension polymerization in silicone oil (2006) Macromol. Rapid Commun, 27 (14), pp. 1180-1184WHITCOMBE, M.J., RODRIGUEZ, M.E., VILLAR, P., VULFSON, E.N., A new method for the introduction of recognition site functionality into polymers prepared by molecular imprinting - synthesies and characterization of polymeric recptors for cholesterol (1995) J. Am. Chem. Soc, 117 (27), pp. 7105-7111WOLMAN, F.J., SMOLKO, E.E., CASCONE, O., GRASSELLI, M., Peptide imprinted polymer synthesized by radiation-induced graft polymerization (2006) React. Funct. Polym, 66 (11), pp. 1199-1205WULFF, G., SARHAN, A., Über die Anwendung von enzymanalog gebauten Polymeren zur Racemattrennung (1972) Angew. Chem, 84 (8), p. 364YE, L., CORMACK, P.A.G., MOSBACH, K., Molecularly imprinted monodisperse microspheres for competitive radioassay (1999) Anal. Commun, 36 (2), pp. 35-38YE, L., CORMACK, P.A.G., MOSBACH, K., Molecular imprinting on microgel spheres (2001) Anal. Chim. Acta, 435 (1), pp. 187-196YILMAZ, E., RAMSTRÖM, O., MÖLLER, P., SANCHEZC, D., MOSBACHA, K., A facile method for preparing molecularly imprinted polymer spheres using spherical silica templates (2002) J. Mater. Chem, 12, pp. 1577-1581YOSHIMATSU, K., REIMHULT, K., KROZER, A., MOSBACH, K., SODE, K., YE, L., Uniform molecularly imprinted microspheres and nanoparticles prepared by precipitation polymerization: The control of particle size suitable for different analytical applications (2007) Anal. Chim. Acta, 584 (1), pp. 112-121YUK, S.H., BAE, Y.H., Phase-transition polymers for drug delivery (1999) Crit. Rev. Ther. Drug Carrier Syst, 16 (4), pp. 385-42
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