402 research outputs found

    Conducting Successful Supervision: Novel Elements Towards an Integrative Approach

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    In recent years that has been an increasing interest in supervision within the UK's cognitive behaviour therapy (CBT) community. This is because the role of supervision has begun to be recognized in relation to the delivery of effective clinical services (Department of Health, 1998), and because of a clear recognition of the need to ensure that CBT practitioners are competent. Perhaps less well recognized in CBT are a number of interesting educational approaches to supervision, ones that may make supervision more successful. This paper summarizes some of these theories from a CBT perspective. Whilst the evidence base does not yet justify being too prescriptive, it is argued that some of these theories, such as Vygotsky's notion of the “Zone of Proximal Development”, provide helpful prompts for reflecting on CBT supervision. An integrative model is constructed from these theories, with illustrative examples and suggestions for future research

    Data-independent neighborhood functions and strict local optima

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    AbstractThe paper proves that data-independent neighborhood functions with the smooth property (all strict local optima are global optima) for maximum 3-satisfiability (MAX 3-SAT) must contain all possible solutions for large instances. Data-independent neighborhood functions with the smooth property for 0–1 knapsack are shown to have size with the same order of magnitude as the cardinality of the solution space. Data-independent neighborhood functions with the smooth property for traveling salesman problem (TSP) are shown to have exponential size. These results also hold for certain polynomially solvable sub-problems of MAX 3-SAT, 0–1 knapsack and TSP

    Sensor node acceleration signatures and electromyography in synchronisation and sequencing analysis in sports: a rowing perspective

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    Following a review of the key determinants of successful rowing, a wireless body sensor network was developed to monitor boat and body segment acceleration and surface electromyography in major muscles recruited during the rowing stroke cycle. Its design was optimised to yield maximum information about the rowing stroke cycle from fewest sensors and minimise the power consumption of the nodes. The system was validated against the Qualisys motion capture and high-speed camera system with most Pearson correlation coefficients in excess of r = 0.8. On-land ergometer experimentation allowed muscle recruitment over the stroke cycle to be studied, with data from multiple experiments combined using correlation of the acceleration signatures of back and thigh nodes (r = 0.95). It was demonstrated that it was possible to identify one of the common rowing errors of ‘shooting-the-slide’ from the data collected, and that a marked decrease in correlation of good-to-bad technique over the drive phase of the stroke (0.95 reducing to 0.34 in the experiment undertaken) could be used to indicate the presence of this error. Extension of the wireless body sensor network to encompass boat and two oarsmen was demonstrated, allowing correlation of their rowing signatures to be studied, indicating their cohesion as a crew

    Challenges When Identifying Migration from Geo-Located Twitter Data

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    Given the challenges in collecting up-to-date, comparable data on migrant populations the potential of digital trace data to study migration and migrants has sparked considerable interest among researchers and policy makers. In this paper we assess the reliability of one such data source that is heavily used within the research community: geolocated tweets. We assess strategies used in previous work to identify migrants based on their geolocation histories. We apply these approaches to infer the travel history of a set of Twitter users who regularly posted geolocated tweets between July 2012 and June 2015. In a second step we hand-code the entire tweet histories of a subset of the accounts identified as migrants by these methods. Upon close inspection very few of the accounts that are classified as migrants appear to be migrants in any conventional sense or international students. Rather we find these approaches identify other highly mobile populations such as frequent business or leisure travellers, or people who might best be described as “transnationals”. For demographic research that draws on this kind of data to generate estimates of migration flows this high mis-classification rate implies that findings are likely sensitive to the adjustment model used. For most research trying to use these data to study migrant populations, the data will be of limited utility. We suspect that increasing the correct classification rate substantially will not be easy and may introduce other biases

    Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1

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    Acknowledgements This work was supported by grants from the Wellcome Trust (200855/Z/16/Z) to MFN and the BBSRC (BB/V010107/1) to MFN and BV. The authors thank Innes Jarmson for the generation of adeno-associated viruses.Peer reviewedPublisher PD

    「環太平洋の言語」日本班

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    初巻は別書誌『消滅に瀕した方言アクセントの緊急調査研究

    Usefulness of the Paralens™ Fluorescent Microscope Adaptor for the Identification of Mycobacteria in Both Field and Laboratory Settings

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    The presence of acid-fast bacilli (AFB) in laboratories has traditionally been demonstrated using the fluorochrome method, which requires a fluorescent microscope or the Ziehl-Neelsen (ZN) method employing light microscopy. Low sensitivity of the ZN method and high costs of fluoroscopy make the need for a more effective means of diagnosis a top priority, especially in developing countries where the burden of tuberculosis is high. The QBC ParaLens™ attachment (QBC Diagnostic Inc., Port Matilda, PA) is a substitute for conventional fluoroscopy in the identification of AFB. To evaluate the efficacy of the ParaLens LED (light-emitting diode) system, the authors performed a two-part study, looking at usefulness, functionality and durability in urban/rural health clinics around the world, as well as in a controlled state public health laboratory setting. In the field, the ParaLens was durable and functioned well with various power sources and lighting conditions. Results from the state laboratory indicated agreement between standard fluorescent microscopy and fluorescent microscopy using the ParaLens. This adaptor is a welcome addition to laboratories in resource-limited settings as a useful alternative to conventional fluoroscopy for detection of mycobacterial species

    Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study.

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    BackgroundSymptom-based screening for tuberculosis is recommended for all people living with HIV. This recommendation results in unnecessary Xpert MTB/RIF testing in many individuals living in tuberculosis-endemic areas and thus poor implementation of intensified case finding and tuberculosis preventive therapy. Novel approaches to tuberculosis screening are needed to help achieve global targets for tuberculosis elimination. We assessed the performance of C-reactive protein (CRP) measured with a point-of-care assay as a screening tool for active pulmonary tuberculosis.MethodsFor this prospective study, we enrolled adults (aged ≥18 years) living with HIV with CD4 cell count less than or equal to 350 cells per μL who were initiating antiretroviral therapy (ART) from two HIV/AIDS clinics in Uganda. CRP concentrations were measured at study entry with a point-of-care assay using whole blood obtained by fingerprick (concentration ≥10 mg/L defined as screen positive for tuberculosis). Sputum samples were collected for Xpert MTB/RIF testing and culture. We calculated the sensitivity and specificity of point-of-care CRP and WHO symptom-based screening in reference to culture results. We repeated the sensitivity analysis with Xpert MTB/RIF as the reference standard.FindingsBetween July 8, 2013, and Dec 15, 2015, 1237 HIV-infected adults were enrolled and underwent point-of-care CRP testing. 60 (5%) patients with incomplete or contaminated cultures were excluded from the analysis. Of the remaining 1177 patients (median CD4 count 165 cells per μL [IQR 75-271]), 163 (14%) had culture-confirmed tuberculosis. Point-of-care CRP testing had 89% sensitivity (145 of 163, 95% CI 83-93) and 72% specificity (731 of 1014, 95% CI 69-75) for culture-confirmed tuberculosis. Compared with WHO symptom-based screening, point-of-care CRP testing had lower sensitivity (difference -7%, 95% CI -12 to -2; p=0·002) but substantially higher specificity (difference 58%, 95% CI 55 to 61; p<0·0001). When Xpert MTB/RIF results were used as the reference standard, sensitivity of point-of-care CRP and WHO symptom-based screening were similar (94% [79 of 84] vs 99% [83 of 84], respectively; difference -5%, 95% CI -12 to 2; p=0·10).InterpretationThe performance characteristics of CRP support its use as a tuberculosis screening test for people living with HIV with CD4 count less than or equal to 350 cells per μL who are initiating ART. HIV/AIDS programmes should consider point-of-care CRP-based tuberculosis screening to improve the efficiency of intensified case finding and increase uptake of tuberculosis preventive therapy.FundingNational Institutes of Health; President's Emergency Plan for AIDS Relief; University of California, San Francisco, Nina Ireland Program for Lung Health
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