Resonant state expansion applied to planar waveguides

The resonant state expansion, a recently developed method in electrodynamics, is generalized here to planar open optical systems with non-normal incidence of light. The method is illustrated and verified on exactly solvable examples, such as a dielectric slab and a Bragg reflector microcavity, for which explicit analytic formulas are developed. This comparison demonstrates the accuracy and convergence of the method. Interestingly, the spectral analysis of a dielectric slab in terms of resonant states reveals an influence of waveguide modes in the transmission. These modes, which on resonance do not couple to external light, surprisingly do couple to external light for off-resonant excitation

Lifetime cost effectiveness of simvastatin in a range of risk groups and age groups derived from a randomised trial of 20,536 people

<i>Objectives</i>: To evaluate the cost effectiveness of 40 mg simvastatin daily continued for life in people of different ages with differing risks of vascular disease. Design A model developed from a randomised trial was used to estimate lifetime risks of vascular events and costs of treatment and hospital admissions in the United Kingdom. <i>Setting</i>: 69 hospitals in the UK. <i>Participants</i>: 20 536 men and women (aged 40-80) with coronary disease, other occlusive arterial disease, or diabetes. <i>Interventions</i>: 40 mg simvastatin daily versus placebo for an average of 5 years. <i>Main</i> <i>outcome</i> <i>measures</i>: Cost effectiveness of 40 mg simvastatin daily expressed as additional cost per life year gained. Major vascular event defined as non-fatal myocardial infarction or death from coronary disease, any stroke, or revascularisation procedure. Results were extrapolated to younger and older age groups at lower risk of vascular disease than were studied directly, as well as to lifetime treatment. <i>Results</i>: At the April 2005 UK price of £4.87 (€7; $9) per 28 day pack of generic 40 mg simvastatin, lifetime treatment was cost saving in most age groups and vascular disease risk groups studied directly. Gains in life expectancy and cost savings decreased with increasing age and with decreasing risk of vascular disease. People aged 40-49 with 5 year risks of major vascular events of 42% and 12% at start of treatment gained 2.49 and 1.67 life years, respectively. Treatment with statins remained cost saving or cost less than £2500 per life year gained in people as young as 35 years or as old as 85 with 5 year risks of a major vascular event as low as 5% at the start of treatment. <i>Conclusions</i>: Treatment with statins is cost effective in a wider population than is routinely treated at present

Transient LTRE analysis reveals the demographic and trait-mediated processes that buffer population growth.

Temporal variation in environmental conditions affects population growth directly via its impact on vital rates, and indirectly through induced variation in demographic structure and phenotypic trait distributions. We currently know very little about how these processes jointly mediate population responses to their environment. To address this gap, we develop a general transient life table response experiment (LTRE) which partitions the contributions to population growth arising from variation in (1) survival and reproduction, (2) demographic structure, (3) trait values and (4) climatic drivers. We apply the LTRE to a population of yellow-bellied marmots (Marmota flaviventer) to demonstrate the impact of demographic and trait-mediated processes. Our analysis provides a new perspective on demographic buffering, which may be a more subtle phenomena than is currently assumed. The new LTRE framework presents opportunities to improve our understanding of how trait variation influences population dynamics and adaptation in stochastic environments

Environmentally induced phenotypic variation in wild yellow-bellied marmots

We thank all the marmoteers who helped in data collection and 2 anonymous reviewers who helped us to clarify our message. AM-C was supported by a Fulbright Fellowship, and JGAM was supported by Fond Québécois de Recherche sur la Nature et les Technologies. KBA was supported by the National Science Foundation between 1962 and 2000. DTB was supported by the National Geographic Society, UCLA (Faculty Senate and the Division of Life Sciences), a Rocky Mountain Biological Laboratory research fellowship, and by the National Science Foundation (IDBR-0754247 and DEB-1119660 to DTB as well as DBI 0242960 and 0731346 to the Rocky Mountain Biological Laboratory).Peer reviewedPostprin

Interpreting the M22 Spike Events

Recently Sahu et al., using the Hubble Space Telescope to monitor stars in the direction of the old globular cluster M22, detected six events in which otherwise constant stars brightened by ~50% during a time of <1 day. They tentatively interpret these unresolved events as due to microlensing of background bulge stars by free-floating planets in M22. I show that if these spike events are due to microlensing, the lensing objects are unlikely to be associated with M22, and unlikely to be part of a smoothly distributed Galactic population. Thus either there happens to be a massive, dark cluster of planets along our line-of-sight to M22, or the spike events are not due to microlensing. The lensing planets cannot be bound to stars in the core of M22: if they were closer than 8 AU, the lensing influence of the parent star would have been detectable. Moreover, in the core of M22, all planets with separations > 1 AU would have been ionized by random stellar encounters. Most unbound planets would have escaped the core via evaporation which preferentially affects such low-mass objects. Bound or free-floating planets can exist in the outer halo of M22; however, for reasonable assumptions, the maximum optical depth to such a population falls short of the observed optical depth, tau ~ 3x10^{-6}, by a factor of 5-10. Therefore, if real, these events represent the detection of a significant free-floating Galactic planet population. The optical depth to these planets is comparable to and mutually exclusive from the optical depth to resolved events measured by microlensing survey collaborations toward the bulge, and thus implies a similar additional mass of lensing objects. Such a population is difficult to reconcile with both theory and observations.Comment: Minor changes. 12 pages, 4 figures, 2 tables. Accepted to ApJ. To appear in Feb 10, 2002 issue (v566

Radiation induced warping of protostellar accretion disks

We examine the consequences of radiatively driven warping of accretion disks surrounding pre-main-sequence stars. These disks are stable against warping if the luminosity arises from a steady accretion flow, but are unstable at late times when the intrinsic luminosity of the star overwhelms that provided by the disk. Warps can be excited for stars with luminosities of around 10 solar luminosities or greater, with larger and more severe warps in the more luminous systems. A twisted inner disk may lead to high extinction towards stars often viewed through their disks. After the disk at all radii becomes optically thin, the warp decays gradually on the local viscous timescale, which is likely to be long. We suggest that radiation induced warping may account for the origin of the warped dust disk seen in Beta Pictoris, if the star is only around 10-20 Myr old, and could lead to non-coplanar planetary systems around higher mass stars.Comment: 12 pages, including 3 figures. ApJ Letters, in pres