Mini nutritional assessment scale-short form can be useful for frailty screening in older adults

Aim: Mini Nutritional Assessment-Short Form (MNA-SF) is used to assess nutritional status in older adults, but it is not known whether it can define frailty. It was aimed to investigate that the MNA-SF can identify frailty status defined by Fried criteria. Methods: 1003 outpatients aged 65 or older were included the study. All patients were performed comprehensive geriatric assessment. Frailty status was evaluated by Fried criteria: unintentional weight loss, exhaustion, low levels of activity, weakness and slowness. 1 point is assigned for each criterion: 0 points, not frail; 1-2 points, prefrail; ≥3 points, frail. If the total score of MNA-SF was 11, it was accepted that there was malnutrition, risk of malnutrition, and no malnutrition, respectively. Results: Of the 1003 outpatients, of whom the mean age was 74.2 ± 8.5 years, 313 participants (31.2%) were considered frail and 382 (38.1%) pre-frail. Among frail patients and pre-frail patients, 49.2 and 25.1% were at risk of malnutrition and 22.0% and 1.6% were malnourished, respectively. MNA-SF with a cut-off point of 11.0 had a sensitivity of 71.2% and a specificity of 92.8% to detect frail participants, and with a cut-off point of 13 had a sensitivity of 45.7% and a specificity of 78.3% to detect pre-frailty. The area under the curve of MNA-SF was 0.906 and 0.687 for the estimation of frailty and pre-frailty, respectively. Conclusion: MNA-SF can be useful for frailty screening in older adults

Nutritional profiles of older adults according the Mini-Nutritional Assessment

Background Malnutrition among older adults plays an important role in clinical and functional impairment. Aims The aim of our study was to evaluate all parameters of Mini-Nutritional Assessment (MNA), according to the nutritional status and to define the risk factors that may cause at risk of malnutrition and malnutrition in more detail. Methods One thousand outpatients aged 65 years or older who underwent the Comprehensive Geriatric Assessment (CGA) were included the study. Results A total of 1000 patients (men vs women; 27.1% vs 72.9%), of whom the mean age was 74.30 +/- 8.28, were enrolled. We found that 6.6% of patients were malnourished, 31.6% of patients were at risk of malnutrition and 61.8% of patients were well-nourished. The mean MNA score was 23.71 +/- 4.19. In patients with malnourished subgroup, the parameters that cause the most loss of points were self-perception of health (87.9%), protein intake (86.4%) and taking at least 3 medications per day (77.3%). At the risk of malnutrition subgroup, protein intake (86.7%), self-perception of health (74.7%) and taking at least 3 medications per day (65.2%) were the three parameters that cause the most loss of points. Discussion In the at-risk and malnourished subgroups, perception of health status, protein intake and taking at least three medications per day were the same MNA parameters that cause the most loss of points, but the rates were different. Conclusions A nutritional intervention should be done as soon as possible in patients who are at risk of malnutrition

Comparison of Plateletpheresis on the Haemonetics and Trima Accel Cell Separators

The use of apheresis equipment to collect platelets has rapidly increased in recent years. We compared two apheresis instruments (Haemonetics MCS+and Trima Accel) with regard to platelet (PLT) yield and efficiency, and collection rate (CR) in a retrospective study. Overall 120 data obtained by Haemonetics and Trima systems (N=60 for each) were randomly selected among 400 plateletpheresis procedures performed at the Apheresis Unit of Kayseri Education and Research Hospital between July 2016 and January 2017. The CR was significantly higher with the Haemonetics compared to the Trima (0.076 +/- 0.016 vs. 0.065 +/- 0.015 (PLTx10(11)/min) respectively; P<0.001). The PLT yield/unit was higher with the Haemonetics (4.4 +/- 0.8 vs. 3.9 +/- 0.8x10(11), P=0.001). Haemonetics and Trima Accel instruments collected platelets efficiently. We hope that these data will be a guide in selecting equipment for apheresis units

Vitamin B12 and folate deficiencies are not associated with nutritional or weight status in older adults

It is not known whether undernutrition causes vitamin B12 and folate deficiencies. The present study aimed to determine whether nutritional status, measured using the Mini Nutritional Assessment (MNA) scale, and body mass index (BMI) are indicators of lower level serum vitamin B12 and folate in older adults. 1007 outpatients aged 65 years or over were included the study. MNA scores >23.5, 17-23.5, 0.05). The results were the same across BMI classifications (p>0.05). Vitamin B12 and folate levels are not associated with nutritional or weight status and these should be evaluated independently of BMI and MNA values

THERE IS A RELATION BETWEEN BLOOD SUBGROUPS AND INSULIN RESISTANCE

Objective: Effects of concomitance of genetic factors with diabetes mellitus have been researched for a long time. We investigated relationship between insulin resistance and ABO/Rh blood group systems, which has not been investigated before