61 research outputs found
Measurement of Direct Photon Emission in K^+ -> pi^+ pi^0 gamma Decay
We have performed a measurement of the K^+ -> pi^+ pi^0 gamma decay and have
observed 2 X 10^4 events. The best fit to the decay spectrum gives a branching
ratio for direct photon emission of (4.7\pm0.8\pm0.3) X 10^{-6} in the pi^+
kinetic energy region of 55 to 90 MeV and requires no component due to
interference with inner bremsstrahlung.Comment: 9 pages, 3 figures. To be submitted to PR
Search for the decay in the momentum region
We have searched for the decay in the kinematic
region with pion momentum below the peak. One event was
observed, consistent with the background estimate of . This
implies an upper limit on
(90% C.L.), consistent with the recently measured branching ratio of
, obtained using the standard model
spectrum and the kinematic region above the peak. The
same data were used to search for , where is a weakly
interacting neutral particle or system of particles with .Comment: 4 pages, 2 figure
Topoisomerase II\u3b2 mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs
The mesenchymal state in cancer is usually associated with poor prognosis due to the metastatic predisposition and the hyper-activated metabolism. Exploiting cell glucose metabolism we propose a new method to detect mesenchymal-like cancer cells. We demonstrate that the uptake of glucose-coated magnetic nanoparticles (MNPs) by mesenchymal-like cells remains constant when the glucose in the medium is increased from low (5.5 mM) to high (25 mM) concentration, while the MNPs uptake by epithelial-like cells is significantly reduced. These findings reveal that the glucose-shell of MNPs plays a major role in recognition of cells with high-metabolic activity. By selectively blocking the glucose transporter 1 channels we showed its involvement in the internalization process of glucose-coated MNPs. Our results suggest that glucose-coated MNPs can be used for metabolic-based assays aimed at detecting cancer cells and that can be used to selectively target cancer cells taking advantage, for instance, of the magnetic-thermotherapy
Measurement of the Branching Ratio
Experiment E949 at Brookhaven National Laboratory studied the rare decay
\ and other processes with an exposure of 's. The data were analyzed using a blind analysis technique
yielding one candidate event with an estimated background of
events. Combining this result with the observation of two candidate events by
the predecessor experiment E787 gave the branching ratio
{\calB}(K^+\to\pi^+\nu\bar{\nu})=(1.47^{+1.30}_{-0.89})\times 10^{-10},
consistent with the Standard Model prediction of . This is a more detailed report of results previously published in
Physical Review Letters.Comment: 99 pages, 32 figures, 12 tables. Added authors, corrected typos and
modify the text suggested by the referees. Accepted for publication in PR
From tests of discrete symmetries to medical imaging with J-PET detector
We present results on CPT symmetry tests in decays of positronium performed with the precision at the level of 10, and positronium images determined with the prototype of the J-PET tomograph. The first full-scale prototype apparatus consists of 192 plastic scintillator strips readout from both ends with vacuum tube photomultipliers. Signals produced by photomultipliers are probed in the amplitude domain and are digitized by FPGA-based readout boards in triggerless mode. In this contribution we report on the first two- and three-photon positronium images and tests of CPT symmetry in positronium decays
Further search for the decay in the momentum region P < 195 MeV/c
We report the results of a search for the decay
in the kinematic region with momentum MeV/c using the
data collected by the E787 experiment at BNL. No events were observed. When
combined with our previous search in this region, one candidate event with an
expected background of events results in a 90% C.L. upper limit
of on the branching ratio of .
We also report improved limits on the rates of and where are hypothetical, massless, long-lived
neutral particles.Comment: 5 pages, 3 figures, Accepted for publication in Phys. Rev.
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