86 research outputs found
Spaces of entire functions represented by vector valued Dirichlet series of two complex variables
Let Y be the space of all entire functions f : โ2 โ E defined by the vector valued Dirichlet series, where E is a complex Banach algebra with the unit element. We study various topologies defined on the space Y and characterize continuous linear transformations on Y
An Enhanced K-Medoid Clustering Algorithm
Data mining is a technique of mining information from the raw data. It is a non trivial process of identifying valid and useful patterns in data. Some of the major Data Mining techniques used for analysis are Association, Classification and Clustering etc. Clustering is used to group homogenous kind of data, but it is different approach from classification process. In the classification process data is grouped on the predefined domains or subjects. A basic clustering technique represents a list of topics for each data and calculates the distance for how accurately a data fit into a group. The Cluster is helpful to get fascinating patterns and structures from an outsized set of knowledge. There are a lots of clustering algorithms that have been proposed and they can be divided as: partitional, grid, density, model and hierarchical based. This paper propose the new enhanced algorithm for k-medoid clustering algorithm which eliminates the deficiency of existing k-medoid algorithm. It first calculates the initial medoids โkโ as per needs of users and then gives relatively better cluster. It follows an organized way to generate initial medoid and applies an effective approach for allocation of data points into the clusters. It reduces the mean square error without sacrificing the execution time and memory use as compared to the existing k-medoid algorithm
Kinetic Characterization and Partial Purification of Peroxidase in Eucalyptus F1 Hybrids
A differential pattern of peroxidase (E.C. 1.1.11.7) has been observed in reciprocal F1 hybrids of Eucalyptus (FRI-4 and FRI-5) produced using parental combination of E. tereticornis and E. camaldulensis. The hybrids were characterized for the qualitative, kinetic parameters (total and specific activity, units, Km and Vmax) and partial purification of peroxidase. The qualitative study showed the presence of high molecular weight peroxidase isoforms i.e. 260 KD, 250 KD and 110KD bands. A strong maternal inheritance was observed for 260 KD loci in FRI-5. Kinetic characterization of peroxidase revealed that F1 genotypes had efficient peroxidase system over their parental combination resulting in 8 -10 times more heterotic vigour. The FRI-5 genotypes were found to be having efficient peroxidase system with lowest Km values (0.12mM-0.17mM) and higher Vmax values ranging from 0.07-0.14mM min-1mg prot-1. The study revealed the role of maternal inheritance and was found that better genotypes are produced when superior parents are used as seed parent. The results suggest the efficient use of peroxidase marker for the identification of the better genotypes in forest tree species.
 
Quantitative Determination and Source Variation of Rutin in Fagopyrum Tataricum
Buckwheat (Fagopyrum sp.) is a traditional crop of Uttarakhand (India) known for its high Rutin content, a bioflavonoid with significant medicinal properties. This study explores the quantitative measurement of Rutin in various buckwheat varieties grown in different regions of Uttarakhand using Thin Layer Chromatography (TLC) and High-Performance Thin Layer Chromatography (HPTLC). Twelve seed sources of Fagopyrum tataricum from the Garhwal and Kumaon regions, along with Fagopyrum esculentum seeds for comparison, were collected. Preliminary phytochemical screening of the extracts revealed the presence of flavonoids, alkaloids, tannins, and carbohydrates, with methanolic extracts showing higher concentrations. TLC analysis was employed to determine the most effective solvent system for Rutin separation, leading to the identification of three samples with substantial Rutin content. HPTLC was then used for quantitative Rutin assessment, with a calibration curve established using standard Rutin solutions. The three selected samples, along with the standard, were applied to HPTLC plates, and the Rutin content was measured based on peak areas and peak heights. The sample collected from Joshimath, Uttarakhand, known as "JOG," exhibited the highest Rutin content. This study provides valuable insights into the phytochemical composition of buckwheat varieties in Uttarakhand, which can inform the development of high-quality functional foods. Rutin, a potent antioxidant with various health benefits, underscores the significance of buckwheat as a naturally occurring functional food source. The results contribute to understanding the Rutin-rich potential of buckwheat grown in Uttarakhand and its applications in functional foods and nutraceuticals. Further research in this field can promote the cultivation and utilization of buckwheat as a source of this valuable bioactive compound with numerous health benefits
Temperature and terahertz frequency dependence of the dielectric properties of Fe3O4 thin films deposited on Si substrate
The FeO/Si films are considered to be promising materials for THz
spintronic applications due to their high temperature magnetic transition and
semiconducting properties. In this article, we present the real part of the
dielectric constant () and the optical conductivity () of
FeO films of different thicknesses deposited on Si substrate
(FeO/Si) in the THz range at temperatures 2- 300 K. Although the
magnetization of the films with thickness 115 nm shows a clear change at
the Verwey transition temperature T = 121 K, their optical properties in
the THz frequency range are drastically different from each other. We have
shown that is maximum and is minimum when the
Fe/Fe ratio is equal to 0.54 which is the ratio of Fe+2/Fe+3 for
pure FeO. The reduces and increases at all
temperatures when the Fe/Fe ratio deviates from 0.54. We have
shown that a slight change in the Fe/Fe ratio can induce large
changes in the optical properties which shall have implications in the
application of the Fe3O4 films in THz spintronics.Comment: 18 pages, 6 figure
Phytochemical Analysis And Evaluation Of Antioxidant Activity In Fagopyrum Esculentum
Herbal nutraceutical products have become increasingly popular in recent years, particularly in the dermatology and cosmetics fields, because of their potential to prevent skin photodamage and their photoprotective qualities against UV radiation. Standardized herbal extracts are necessary for modern phytopharmaceutics and phytocosmetics, and buckwheat herb, which is high in flavonoids, has shown promise as an antioxidant source. The objective of the research is to ascertain the existence of various nutraceutical components in buckwheat, such as proteins, carbohydrates, sterols, alkaloids, saponins, and tannins, both quantitatively and qualitatively. The study assesses possible interactions between these components, food, and prescribed medications as the body of research on their health benefits grows. Through a variety of phytochemical tests, the results show the high antioxidant and nutraceutical qualities of Fagopyrum esculentum, with methanolic extracts showing greater activity than water extracts. Notably, the study highlights the high antioxidant activity, alkaloids, flavonoids, tannins, and phenolic compounds of F. esculentum as potential major food supplement. This study offers a biochemical justification for its application in ethnopharmacology and as a nutraceutical to improve health and prevent a variety of ailment
Bio-Ecology of the Louse, Upupicola upupae, Infesting the Common Hoopoe, Upupa epops
The population characteristics of the louse, Upupicola upupae (Shrank) (Mallophaga: Philopteridae: Ishnocera), infesting the Common Hoopae, Upupa epops L. (Aves: Upupiformes), were recorded during 2007โ08 in District Rampur, Uttar Pradesh India. The pattern of frequency distribution of the louse conformed to the negative binomial model. The lice and its nits were reared in vitro at 35 ยฑ 1ยฐ C, 75โ82 % RH, on a feather diet. The data obtained was used to construct the life table and to determine the intrinsic rate of natural increase (0.035 female/day), the net reproductive rate was 3.67 female eggs/female, the generation time was 37 days, and the doubling time of the population was 19 days. The chaetotaxy of the three nymphal instars has also been noted to record their diagnostic characteristics. Information on egg morphology and antennal sensilla is also presented
Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors
Histone deacetylase (HDAC) inhibitors are being intensively pursued as potential new drugs for a range of diseases, including malaria. HDAC inhibitors are also important tools for the study of epigenetic mechanisms, transcriptional control, and other important cellular processes. In this study the effects of three structurally related antimalarial HDAC inhibitors on P. falciparum malaria parasite gene expression were compared. The three hydroxamate-based compounds, trichostatin A (TSA), suberoylanilide hydroxamic acid (SAHA; Vorinostatยฎ) and a 2-aminosuberic acid derivative (2-ASA-9), all caused profound transcriptional effects, with โผ2โ21% of genes having >2-fold altered expression following 2 h exposure to the compounds. Only two genes, alpha tubulin II and a hydrolase, were up-regulated by all three compounds after 2 h exposure in all biological replicates examined. The transcriptional changes observed after 2 h exposure to HDAC inhibitors were found to be largely transitory, with only 1โ5% of genes being regulated after removing the compounds and culturing for a further 2 h. Despite some structural similarity, the three inhibitors caused quite diverse transcriptional effects, possibly reflecting subtle differences in mode of action or cellular distribution. This dataset represents an important contribution to our understanding of how HDAC inhibitors act on malaria parasites and identifies alpha tubulin II as a potential transcriptional marker of HDAC inhibition in malaria parasites that may be able to be exploited for future development of HDAC inhibitors as new antimalarial agents
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